Effects of liraglutide in hypothalamic arcuate nucleus of obese mice
暂无分享,去创建一个
[1] C. Hölscher,et al. Restoration of Cerebral and Systemic Microvascular Architecture in APP/PS1 Transgenic Mice Following Treatment with Liraglutide™ , 2015, Microcirculation.
[2] S. Briyal,et al. Neuroprotective and anti-apoptotic effects of liraglutide in the rat brain following focal cerebral ischemia , 2014, Neuroscience.
[3] J. Hecksher-Sørensen,et al. The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss. , 2014, The Journal of clinical investigation.
[4] T. Ando,et al. Liraglutide as a potentially useful agent for regulating appetite in diabetic patients with hypothalamic hyperphagia and obesity. , 2014, Internal medicine.
[5] L. Miller-Fleming,et al. Microglia and inflammation: conspiracy, controversy or control? , 2014, Cellular and Molecular Life Sciences.
[6] Nu-Chu Liang,et al. Long term exendin-4 treatment reduces food intake and body weight and alters expression of brain homeostatic and reward markers. , 2014, Endocrinology.
[7] C. Hölscher. Central effects of GLP-1: new opportunities for treatments of neurodegenerative diseases. , 2014, The Journal of endocrinology.
[8] R. Seeley,et al. Hormones and diet, but not body weight, control hypothalamic microglial activity , 2014, Glia.
[9] J. Jansson,et al. Glucagon-like peptide 1 receptor induced suppression of food intake, and body weight is mediated by central IL-1 and IL-6 , 2013, Proceedings of the National Academy of Sciences.
[10] T. Rabelink,et al. Glucagon-like peptide-1 receptor agonist treatment reduces beta cell mass in normoglycaemic mice , 2013, Diabetologia.
[11] Elizabeth K. Unger,et al. Modulation of AgRP-neuronal function by SOCS3 as an initiating event in diet-induced hypothalamic leptin resistance , 2013, Proceedings of the National Academy of Sciences.
[12] C. Hölscher,et al. Liraglutide protects against amyloid-β protein-induced impairment of spatial learning and memory in rats , 2013, Neurobiology of Aging.
[13] M. Deyoung,et al. GLP-1 receptor activated insulin secretion from pancreatic β-cells: mechanism and glucose dependence , 2012, Diabetes, obesity & metabolism.
[14] C. Mandarim-de-Lacerda,et al. Maternal High-Fat Diet Programs for Metabolic Disturbances in Offspring despite Leptin Sensitivity , 2012, Neuroendocrinology.
[15] C. Hölscher,et al. Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis , 2012, BMC Neuroscience.
[16] M. R. Hayes,et al. GLP-1 neurons in the nucleus of the solitary tract project directly to the ventral tegmental area and nucleus accumbens to control for food intake. , 2012, Endocrinology.
[17] Joshua A. Smith,et al. Role of pro-inflammatory cytokines released from microglia in neurodegenerative diseases , 2012, Brain Research Bulletin.
[18] M. Dietrich,et al. Obesity is associated with hypothalamic injury in rodents and humans. , 2012, The Journal of clinical investigation.
[19] H. Grill,et al. Peripheral and central GLP-1 receptor populations mediate the anorectic effects of peripherally administered GLP-1 receptor agonists, liraglutide and exendin-4. , 2011, Endocrinology.
[20] Christian Hölscher,et al. The Diabetes Drug Liraglutide Prevents Degenerative Processes in a Mouse Model of Alzheimer's Disease , 2011, The Journal of Neuroscience.
[21] C. Hölscher,et al. Novel GLP‐1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain , 2011, Journal of neuroscience research.
[22] H. Grill,et al. Intracellular signals mediating the food intake-suppressive effects of hindbrain glucagon-like peptide-1 receptor activation. , 2011, Cell metabolism.
[23] M. Cowley,et al. Diet-induced obesity causes ghrelin resistance in arcuate NPY/AgRP neurons. , 2010, Endocrinology.
[24] L. B. Knudsen. Liraglutide: the therapeutic promise from animal models , 2010, International journal of clinical practice. Supplement.
[25] S. Griffen,et al. Chronic Administration of the Glucagon-Like Peptide-1 Analog, Liraglutide, Delays the Onset of Diabetes and Lowers Triglycerides in UCD-T2DM Rats , 2010, Diabetes.
[26] Jens C. Brüning,et al. Integrative neurobiology of energy homeostasis-neurocircuits, signals and mediators , 2010, Frontiers in Neuroendocrinology.
[27] J. Friedman. Obesity: Causes and control of excess body fat , 2009, Nature.
[28] J. Carvalheira,et al. High-Fat Diet Induces Apoptosis of Hypothalamic Neurons , 2009, PloS one.
[29] J. Carvalheira,et al. Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity , 2009, The Journal of Neuroscience.
[30] H. Neumann,et al. Debris clearance by microglia: an essential link between degeneration and regeneration , 2008, Brain : a journal of neurology.
[31] Kathryn Moynihan Ramsey,et al. High-fat diet disrupts behavioral and molecular circadian rhythms in mice. , 2007, Cell metabolism.
[32] M. W. Schwartz,et al. Central nervous system control of food intake and body weight , 2006, Nature.
[33] M. Morris,et al. Adaptive responses in hypothalamic neuropeptide Y in the face of prolonged high‐fat feeding in the rat , 2003, Journal of neurochemistry.
[34] J. Hwa,et al. Characterization of diet-induced obese rats that develop persistent obesity after 6 months of high-fat followed by 1 month of low-fat diet , 2002, Brain Research.
[35] George Paxinos,et al. The Mouse Brain in Stereotaxic Coordinates , 2001 .
[36] C. Mantzoros,et al. Differential expression of hypothalamic neuropeptides in the early phase of diet-induced obesity in mice. , 2000, American journal of physiology. Endocrinology and metabolism.
[37] S. Woods,et al. Central nervous system control of food intake , 2000, Nature.
[38] P. G. Reeves,et al. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. , 1993, The Journal of nutrition.
[39] H. Gundersen,et al. Notes on the estimation of the numerical density of arbitrary profiles: the edge effect , 1977 .