Targeting cancer cells with biotin-dendrimer conjugates.

[1]  T. Xu,et al.  Dendrimer-based prodrugs: design, synthesis, screening and biological evaluation. , 2007, Combinatorial chemistry & high throughput screening.

[2]  A. D'emanuele,et al.  In vitro evaluation of dendrimer prodrugs for oral drug delivery. , 2007, International journal of pharmaceutics.

[3]  N. Vorsa,et al.  Dendrimer versus linear conjugate: Influence of polymeric architecture on the delivery and anticancer effect of paclitaxel. , 2006, Bioconjugate chemistry.

[4]  Thommey P. Thomas,et al.  HER2 specific tumor targeting with dendrimer conjugated anti-HER2 mAb. , 2006, Bioconjugate chemistry.

[5]  A. Mitra,et al.  Biotin uptake and cellular translocation in human derived retinoblastoma cell line (Y-79): a role of hSMVT system. , 2006, International journal of pharmaceutics.

[6]  Jayant Khandare,et al.  Polymer-drug conjugates: Progress in polymeric prodrugs , 2006 .

[7]  A. Mitra,et al.  Functional characterization of sodium-dependent multivitamin transporter in MDCK-MDR1 cells and its utilization as a target for drug delivery. , 2006, Molecular pharmaceutics.

[8]  Umesh Gupta,et al.  Dendrimers: novel polymeric nanoarchitectures for solubility enhancement. , 2006, Biomacromolecules.

[9]  Sally Freeman,et al.  Synthesis, characterization and stability of dendrimer prodrugs. , 2006, International journal of pharmaceutics.

[10]  Thommey P. Thomas,et al.  PAMAM dendrimer-based multifunctional conjugate for cancer therapy: synthesis, characterization, and functionality. , 2006, Biomacromolecules.

[11]  R. Duncan,et al.  Dendrimer biocompatibility and toxicity. , 2005, Advanced drug delivery reviews.

[12]  A. Schätzlein,et al.  Dendrimers in gene delivery. , 2005, Advanced drug delivery reviews.

[13]  Anil K Patri,et al.  Targeted drug delivery with dendrimers: comparison of the release kinetics of covalently conjugated drug and non-covalent drug inclusion complex. , 2005, Advanced drug delivery reviews.

[14]  Donald A Tomalia,et al.  Dendrimers in biomedical applications--reflections on the field. , 2005, Advanced drug delivery reviews.

[15]  Thommey P. Thomas,et al.  Tumor angiogenic vasculature targeting with PAMAM dendrimer-RGD conjugates. , 2005, Chemical communications.

[16]  Abhay Asthana,et al.  Poly(amidoamine) (PAMAM) dendritic nanostructures for controlled sitespecific delivery of acidic anti-inflammatory active ingredient , 2005, AAPS PharmSciTech.

[17]  Thommey P. Thomas,et al.  Poly(amidoamine) dendrimer-based multifunctional engineered nanodevice for cancer therapy. , 2005, Journal of medicinal chemistry.

[18]  J. Zempleni,et al.  Biotin availability regulates expression of the sodium-dependent multivitamin transporter and the rate of biotin uptake in HepG2 cells. , 2005, Molecular genetics and metabolism.

[19]  Thommey P. Thomas,et al.  Nanoparticle targeting of anticancer drug improves therapeutic response in animal model of human epithelial cancer. , 2005, Cancer research.

[20]  N. K. Jain,et al.  Glycodendrimeric nanoparticulate carriers of primaquine phosphate for liver targeting. , 2005, International journal of pharmaceutics.

[21]  Thommey P. Thomas,et al.  Targeting and inhibition of cell growth by an engineered dendritic nanodevice. , 2005, Journal of medicinal chemistry.

[22]  D. Tomalia Birth of a new macromolecular architecture: dendrimers as quantized building blocks for nanoscale synthetic polymer chemistry , 2005 .

[23]  P. Heegaard,et al.  Dendrimers in drug research. , 2004, Chemical Society reviews.

[24]  M. Ciesielski,et al.  Boronated epidermal growth factor as a delivery agent for neutron capture therapy of EGF receptor positive gliomas. , 2004, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

[25]  M. Ciesielski,et al.  Neutron capture therapy of epidermal growth factor (+) gliomas using boronated cetuximab (IMC-C225) as a delivery agent. , 2004, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

[26]  Thommey P. Thomas,et al.  Synthesis and in vitro testing of J591 antibody-dendrimer conjugates for targeted prostate cancer therapy. , 2004, Bioconjugate chemistry.

[27]  D. Nowotnik,et al.  Vitamin-mediated targeting as a potential mechanism to increase drug uptake by tumours. , 2004, Journal of inorganic biochemistry.

[28]  Antony D'Emanuele,et al.  The use of a dendrimer-propranolol prodrug to bypass efflux transporters and enhance oral bioavailability. , 2004, Journal of controlled release : official journal of the Controlled Release Society.

[29]  S. Jain,et al.  A PEGylated dendritic nanoparticulate carrier of fluorouracil. , 2003, International journal of pharmaceutics.

[30]  Hoo-Kyun Choi,et al.  Self-assembled nanoparticles of hydrophobically-modified polysaccharide bearing vitamin H as a targeted anti-cancer drug delivery system. , 2003, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[31]  P. Mishra,et al.  Biotinylated methotrexate loaded erythrocytes for enhanced liver uptake. 'A study on the rat'. , 2002, International journal of pharmaceutics.

[32]  D. Tomalia,et al.  Poly(amidoamine) (PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications. , 2001, Drug discovery today.

[33]  N. McKeown,et al.  Polyamidoamine Starburst dendrimers as solubility enhancers. , 2000, International journal of pharmaceutics.

[34]  M C Davies,et al.  A novel biotinylated degradable polymer for cell-interactive applications. , 1998, Biotechnology and bioengineering.

[35]  H. Gruber,et al.  Biotin-pyrene conjugates with poly(ethylene glycol) spacers are convenient fluorescent probes for avidin and streptavidin. , 1997, Bioconjugate chemistry.

[36]  E. Meijer,et al.  Encapsulation of Guest Molecules into a Dendritic Box , 1994, Science.

[37]  T. Xu,et al.  Dendrimers as drug carriers: applications in different routes of drug administration. , 2008, Journal of pharmaceutical sciences.

[38]  T. Xu,et al.  Pharmaceutical applications of dendrimers: promising nanocarriers for drug delivery. , 2008, Frontiers in bioscience : a journal and virtual library.

[39]  Thommey P. Thomas,et al.  Synthesis and functional evaluation of DNA-assembled polyamidoamine dendrimer clusters for cancer cell-specific targeting. , 2005, Chemistry & biology.

[40]  K. Yarema,et al.  Targeting cancer cells with dendrimers. , 2005, Chemistry & biology.

[41]  Antony D'Emanuele,et al.  Dendrimer-drug interactions. , 2005, Advanced drug delivery reviews.

[42]  J. Fréchet,et al.  Dendrimers and dendritic polymers in drug delivery. , 2005, Drug discovery today.