Regulation of microRNAs in cancer metastasis.

[1]  Kun Wang,et al.  Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1 , 2014, Oncogene.

[2]  H. Zhang,et al.  MicroRNA-145 inhibits the growth, invasion, metastasis and angiogenesis of neuroblastoma cells through targeting hypoxia-inducible factor 2 alpha , 2014, Oncogene.

[3]  J. Qin,et al.  MicroRNA‐221 promotes colorectal cancer cell invasion and metastasis by targeting RECK , 2014, FEBS letters.

[4]  R. Qin,et al.  Direct targeting of SUZ12/ROCK2 by miR-200b/c inhibits cholangiocarcinoma tumourigenesis and metastasis , 2013, British Journal of Cancer.

[5]  D. Marchetti,et al.  MicroRNA and Protein Profiling of Brain Metastasis Competent Cell-Derived Exosomes , 2013, PloS one.

[6]  A. Luo,et al.  MicroRNA-34 suppresses breast cancer invasion and metastasis by directly targeting Fra-1 , 2013, Oncogene.

[7]  Min Deng,et al.  miR-26a Suppresses Tumor Growth and Metastasis by Targeting FGF9 in Gastric Cancer , 2013, PloS one.

[8]  D. Fan,et al.  Regulation of UHRF1 by miR‐146a/b modulates gastric cancer invasion and metastasis , 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[9]  Sirong He,et al.  MicroRNA-221 Mediates the Effects of PDGF-BB on Migration, Proliferation, and the Epithelial-Mesenchymal Transition in Pancreatic Cancer Cells , 2013, PloS one.

[10]  L. Tang,et al.  miRNA-29c Suppresses Lung Cancer Cell Adhesion to Extracellular Matrix and Metastasis by Targeting Integrin β1 and Matrix Metalloproteinase2 (MMP2) , 2013, PloS one.

[11]  Wenlin Huang,et al.  Genetic and epigenetic down-regulation of microRNA-212 promotes colorectal tumor metastasis via dysregulation of MnSOD. , 2013, Gastroenterology.

[12]  Yu Wang,et al.  MicroRNA-143 Inhibits Migration and Invasion of Human Non-Small-Cell Lung Cancer and Its Relative Mechanism , 2013, International journal of biological sciences.

[13]  Q. Ye,et al.  MicroRNA‐26a suppresses tumor growth and metastasis of human hepatocellular carcinoma by targeting interleukin‐6‐Stat3 pathway , 2013, Hepatology.

[14]  D. Dornan,et al.  miR-221/222 Targets Adiponectin Receptor 1 to Promote the Epithelial-to-Mesenchymal Transition in Breast Cancer , 2013, PloS one.

[15]  B. Bao,et al.  Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review , 2013, Cancer and Metastasis Reviews.

[16]  Yih-Leong Chang,et al.  MicroRNA-135b promotes lung cancer metastasis by regulating multiple targets in the Hippo pathway and LZTS1 , 2013, Nature Communications.

[17]  Rounak Nassirpour,et al.  miR-221 Promotes Tumorigenesis in Human Triple Negative Breast Cancer Cells , 2013, PloS one.

[18]  Michael A. Freitas,et al.  In vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation , 2013, The Journal of experimental medicine.

[19]  Samy Lamouille,et al.  Regulation of epithelial-mesenchymal and mesenchymal-epithelial transitions by microRNAs. , 2013, Current opinion in cell biology.

[20]  D. Scadden,et al.  BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. , 2013, The Journal of clinical investigation.

[21]  R. Kalluri,et al.  Exosomes in tumor microenvironment influence cancer progression and metastasis , 2013, Journal of Molecular Medicine.

[22]  R. Askeland,et al.  MicroRNA miR-24 enhances tumor invasion and metastasis by targeting PTPN9 and PTPRF to promote EGF signaling , 2013, Journal of Cell Science.

[23]  H. Baba,et al.  Clinical impact of serum exosomal microRNA‐21 as a clinical biomarker in human esophageal squamous cell carcinoma , 2013, Cancer.

[24]  Tao Li,et al.  MicroRNA-7 functions as an anti-metastatic microRNA in gastric cancer by targeting insulin-like growth factor-1 receptor , 2013, Oncogene.

[25]  M. Zöller,et al.  Exosomal tumor microRNA modulates premetastatic organ cells. , 2013, Neoplasia.

[26]  Shuhan Sun,et al.  Epigenetic activation of the MiR-200 family contributes to H19-mediated metastasis suppression in hepatocellular carcinoma. , 2013, Carcinogenesis.

[27]  Qin Xu,et al.  Downregulation of miR-153 contributes to epithelial-mesenchymal transition and tumor metastasis in human epithelial cancer. , 2013, Carcinogenesis.

[28]  X. Bian,et al.  MicroRNA-137, an HMGA1 target, suppresses colorectal cancer cell invasion and metastasis in mice by directly targeting FMNL2. , 2013, Gastroenterology.

[29]  Ying Sun,et al.  MiR-29c suppresses invasion and metastasis by targeting TIAM1 in nasopharyngeal carcinoma. , 2013, Cancer letters.

[30]  C. Ong,et al.  Overexpression of microRNA-21 regulating PDCD4 during tumorigenesis of liver fluke-associated cholangiocarcinoma contributes to tumor growth and metastasis , 2013, Tumor Biology.

[31]  D. Amadori,et al.  miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis , 2013, Nature Cell Biology.

[32]  Zhiyong Wu,et al.  miR-30a Suppresses Cell Migration and Invasion Through Downregulation of PIK3CD in Colorectal Carcinoma , 2013, Cellular Physiology and Biochemistry.

[33]  V. Marx Tracking metastasis and tricking cancer , 2013, Nature.

[34]  Bao Zhang,et al.  miR-26a inhibits invasion and metastasis of nasopharyngeal cancer by targeting EZH2 , 2013, Oncology letters.

[35]  Min Liu,et al.  MicroRNA‐10a is involved in the metastatic process by regulating Eph tyrosine kinase receptor A4‐Mediated epithelial‐mesenchymal transition and adhesion in hepatoma cells * , 2013, Hepatology.

[36]  Kai Huang,et al.  microRNA-9 Suppresses the Proliferation, Invasion and Metastasis of Gastric Cancer Cells through Targeting Cyclin D1 and Ets1 , 2013, PloS one.

[37]  Z. Werb,et al.  GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression , 2013, Nature Cell Biology.

[38]  Hui Li,et al.  The molecular mechanism of microRNA-145 to suppress invasion–metastasis cascade in gastric cancer , 2013, Oncogene.

[39]  Z. Shao,et al.  MicroRNA-200a Promotes Anoikis Resistance and Metastasis by Targeting YAP1 in Human Breast Cancer , 2013, Clinical Cancer Research.

[40]  W Abou-Kheir,et al.  MiR-1 and miR-200 inhibit EMT via Slug-dependent and tumorigenesis via Slug-independent mechanisms , 2013, Oncogene.

[41]  C. Croce,et al.  A new role for microRNAs, as ligands of Toll-like receptors , 2013, RNA biology.

[42]  H. Kuwano,et al.  MiR‐150 is associated with poor prognosis in esophageal squamous cell carcinoma via targeting the EMT inducer ZEB1 , 2013, Cancer science.

[43]  Fenghua Wang,et al.  Overexpression of paxillin induced by miR-137 suppression promotes tumor progression and metastasis in colorectal cancer , 2012, Carcinogenesis.

[44]  M. He,et al.  MiR-124 targets Slug to regulate epithelial–mesenchymal transition and metastasis of breast cancer , 2012, Carcinogenesis.

[45]  L. Rybak,et al.  Resveratrol Reduces Prostate Cancer Growth and Metastasis by Inhibiting the Akt/MicroRNA-21 Pathway , 2012, PloS one.

[46]  Kai Huang,et al.  miRNA-145 Targets v-ets Erythroblastosis Virus E26 Oncogene Homolog 1 to Suppress the Invasion, Metastasis, and Angiogenesis of Gastric Cancer Cells , 2012, Molecular Cancer Research.

[47]  R. Askeland,et al.  MiR-93 enhances angiogenesis and metastasis by targeting LATS2 , 2012, Cell cycle.

[48]  S. Tavazoie,et al.  Convergent Multi-miRNA Targeting of ApoE Drives LRP1/LRP8-Dependent Melanoma Metastasis and Angiogenesis , 2012, Cell.

[49]  M. Tetzlaff,et al.  miR-200c inhibits melanoma progression and drug resistance through down-regulation of BMI-1. , 2012, The American journal of pathology.

[50]  D. Phinney,et al.  MicroRNAs in the Imprinted DLK1-DIO3 Region Repress the Epithelial-to-Mesenchymal Transition by Targeting the TWIST1 Protein Signaling Network* , 2012, The Journal of Biological Chemistry.

[51]  Weijia Sun,et al.  miR-143 inhibits the metastasis of pancreatic cancer and an associated signaling pathway , 2012, Tumor Biology.

[52]  S. Rai,et al.  Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes , 2012, PloS one.

[53]  M. Pan,et al.  Prospero Homeobox 1 Promotes Epithelial–Mesenchymal Transition in Colon Cancer Cells by Inhibiting E-cadherin via miR-9 , 2012, Clinical Cancer Research.

[54]  H. Xia,et al.  MicroRNAs involved in regulating epithelial–mesenchymal transition and cancer stem cells as molecular targets for cancer therapeutics , 2012, Cancer Gene Therapy.

[55]  Jing Liu,et al.  MicroRNA-21 (miR-21) expression promotes growth, metastasis, and chemo- or radioresistance in non-small cell lung cancer cells by targeting PTEN , 2012, Molecular and Cellular Biochemistry.

[56]  G. Goodall,et al.  ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression. , 2012, The Journal of clinical investigation.

[57]  A. Levine,et al.  Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer , 2012, Proceedings of the National Academy of Sciences.

[58]  Baorui Liu,et al.  microRNA-146a targets the L1 cell adhesion molecule and suppresses the metastatic potential of gastric cancer. , 2012, Molecular medicine reports.

[59]  Ping Li,et al.  MicroRNA-9 suppresses uveal melanoma cell migration and invasion through the NF-κB1 pathway. , 2012, Oncology reports.

[60]  Eun Hee Lee,et al.  Altered expression of microRNA miR‐21, miR‐155, and let‐7a and their roles in pulmonary neuroendocrine tumors , 2012, Pathology international.

[61]  Zhaoshi Jiang,et al.  Tumour‐secreted miR‐9 promotes endothelial cell migration and angiogenesis by activating the JAK‐STAT pathway , 2012, The EMBO journal.

[62]  Aimee L Jackson,et al.  Developing microRNA therapeutics: approaching the unique complexities. , 2012, Nucleic acid therapeutics.

[63]  T. Zhu,et al.  MicroRNA-7 Inhibits Epithelial-to-Mesenchymal Transition and Metastasis of Breast Cancer Cells via Targeting FAK Expression , 2012, PloS one.

[64]  Jianwen Liu,et al.  MiR-139 inhibits invasion and metastasis of colorectal cancer by targeting the type I insulin-like growth factor receptor. , 2012, Biochemical pharmacology.

[65]  Jianfang Li,et al.  Down‐regulated miR‐625 suppresses invasion and metastasis of gastric cancer by targeting ILK , 2012, FEBS letters.

[66]  Hsien-Da Huang,et al.  miR-103/107 promote metastasis of colorectal cancer by targeting the metastasis suppressors DAPK and KLF4. , 2012, Cancer research.

[67]  D. Fan,et al.  Ectopic Expression of MiR-125a Inhibits the Proliferation and Metastasis of Hepatocellular Carcinoma by Targeting MMP11 and VEGF , 2012, PloS one.

[68]  Qiang Zhang,et al.  miR-21 Is a Promising Novel Biomarker for Lymph Node Metastasis in Patients with Gastric Cancer , 2012, Gastroenterology research and practice.

[69]  Y. Toiyama,et al.  MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis , 2012, Gut.

[70]  Manran Liu,et al.  Antagonism of miR-21 Reverses Epithelial-Mesenchymal Transition and Cancer Stem Cell Phenotype through AKT/ERK1/2 Inactivation by Targeting PTEN , 2012, PloS one.

[71]  M. Bar‐eli,et al.  Driving transcriptional regulators in melanoma metastasis , 2012, Cancer and Metastasis Reviews.

[72]  Li Ma,et al.  MicroRNA control of epithelial–mesenchymal transition and metastasis , 2012, Cancer and Metastasis Reviews.

[73]  Tao Xi,et al.  MicroRNA-125b Induces Metastasis by Targeting STARD13 in MCF-7 and MDA-MB-231 Breast Cancer Cells , 2012, PloS one.

[74]  J. Rice Metastasis: The rude awakening , 2012, Nature.

[75]  Liduan Zheng,et al.  microRNA-9 Targets Matrix Metalloproteinase 14 to Inhibit Invasion, Metastasis, and Angiogenesis of Neuroblastoma Cells , 2012, Molecular Cancer Therapeutics.

[76]  H. Allgayer,et al.  MicroRNA‐30a inhibits epithelial‐to‐mesenchymal transition by targeting Snai1 and is downregulated in non‐small cell lung cancer , 2012, International journal of cancer.

[77]  L. Pfeffer,et al.  DNA Damage Induces NF-κB-dependent MicroRNA-21 Up-regulation and Promotes Breast Cancer Cell Invasion* , 2012, The Journal of Biological Chemistry.

[78]  Baoan Ma,et al.  MicroRNA-34a Inhibits the Proliferation and Metastasis of Osteosarcoma Cells Both In Vitro and In Vivo , 2012, PloS one.

[79]  Peng Ru,et al.  miRNA-29b Suppresses Prostate Cancer Metastasis by Regulating Epithelial–Mesenchymal Transition Signaling , 2012, Molecular Cancer Therapeutics.

[80]  J. Li,et al.  MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1 , 2012, Oncogene.

[81]  Zhenggang Zhu,et al.  microRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN , 2012, Oncology reports.

[82]  S. Tavazoie,et al.  A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells , 2011, Nature.

[83]  Y. Yuasa,et al.  MiR‐9 downregulates CDX2 expression in gastric cancer cells , 2011, International journal of cancer.

[84]  Changhong Sun,et al.  Genome-wide functional screening of miR-23b as a pleiotropic modulator suppressing cancer metastasis. , 2011, Nature communications.

[85]  Dihua Yu,et al.  Nucleolin Protein Interacts with Microprocessor Complex to Affect Biogenesis of MicroRNAs 15a and 16* , 2011, The Journal of Biological Chemistry.

[86]  D. Cheresh,et al.  Tumor angiogenesis: molecular pathways and therapeutic targets , 2011, Nature Medicine.

[87]  Jing Ping Zhang,et al.  MicroRNA‐29b suppresses tumor angiogenesis, invasion, and metastasis by regulating matrix metalloproteinase 2 expression , 2011, Hepatology.

[88]  Sheng Tan,et al.  Pivotal role of reduced let-7g expression in breast cancer invasion and metastasis. , 2011, Cancer research.

[89]  Xianghuo He,et al.  MicroRNA-148a Suppresses Tumor Cell Invasion and Metastasis by Downregulating ROCK1 in Gastric Cancer , 2011, Clinical Cancer Research.

[90]  Robert A. Weinberg,et al.  Tumor Metastasis: Molecular Insights and Evolving Paradigms , 2011, Cell.

[91]  F. Su,et al.  Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells , 2011, Molecular Cancer.

[92]  Junming Yue,et al.  MicroRNA miR-21 Regulates the Metastatic Behavior of B16 Melanoma Cells* , 2011, The Journal of Biological Chemistry.

[93]  R. Sreekumar,et al.  MicroRNA Control of Invasion and Metastasis Pathways , 2011, Front. Gene..

[94]  Lixin Wei,et al.  Epithelial-Mesenchymal Transition in tumor microenvironment , 2011, Cell & Bioscience.

[95]  Xiaohua Li,et al.  MicroRNA-107, an oncogene microRNA that regulates tumour invasion and metastasis by targeting DICER1 in gastric cancer , 2011, Journal of cellular and molecular medicine.

[96]  Li Jiang,et al.  MicroRNA-335 acts as a metastasis suppressor in gastric cancer by targeting Bcl-w and specificity protein 1 , 2011, Oncogene.

[97]  G. Camussi,et al.  Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche. , 2011, Cancer research.

[98]  Zhihai Ma,et al.  Up-Regulated Dicer Expression in Patients with Cutaneous Melanoma , 2011, PloS one.

[99]  Ju-Seog Lee,et al.  LIN28B promotes colon cancer progression and metastasis. , 2011, Cancer research.

[100]  Ru-Fang Yeh,et al.  TRPS1 Targeting by miR-221/222 Promotes the Epithelial-to-Mesenchymal Transition in Breast Cancer , 2011, Science Signaling.

[101]  X. Bian,et al.  The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2 , 2011, Gut.

[102]  Heike Allgayer,et al.  Curcumin regulates miR-21 expression and inhibits invasion and metastasis in colorectal cancer. , 2011, Bioscience reports.

[103]  Xin Lu,et al.  Epithelial cell polarity: a major gatekeeper against cancer? , 2011, Cell Death and Differentiation.

[104]  Wei Guo,et al.  Identification of miRs-143 and -145 that Is Associated with Bone Metastasis of Prostate Cancer and Involved in the Regulation of EMT , 2011, PloS one.

[105]  Jiannis Ragoussis,et al.  Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization , 2011, Nature Medicine.

[106]  Francesca Orso,et al.  microRNA‐214 contributes to melanoma tumour progression through suppression of TFAP2C , 2011, The EMBO journal.

[107]  Shengjin Yu,et al.  MiR-34a inhibits lymphatic metastasis potential of mouse hepatoma cells , 2011, Molecular and Cellular Biochemistry.

[108]  Tae Jin Lee,et al.  p53 regulates epithelial–mesenchymal transition through microRNAs targeting ZEB1 and ZEB2 , 2011, The Journal of experimental medicine.

[109]  B. Jiang,et al.  MiR-21 Induced Angiogenesis through AKT and ERK Activation and HIF-1α Expression , 2011, PloS one.

[110]  D. Fan,et al.  MicroRNA Let-7f Inhibits Tumor Invasion and Metastasis by Targeting MYH9 in Human Gastric Cancer , 2011, PloS one.

[111]  Takashi Takata,et al.  miR-22 represses cancer progression by inducing cellular senescence , 2011, The Journal of cell biology.

[112]  W. Grizzle,et al.  miR-155 promotes macroscopic tumor formation yet inhibits tumor dissemination from mammary fat pads to the lung by preventing EMT , 2011, Oncogene.

[113]  R. Weinberg,et al.  Activation of miR-31 function in already-established metastases elicits metastatic regression. , 2011, Genes & development.

[114]  Toshiaki Watanabe,et al.  Clinicopathological and Prognostic Value of MicroRNA-21 and MicroRNA-155 in Colorectal Cancer , 2011, Oncology.

[115]  Chun-Ting Lin,et al.  Let-7b-mediated suppression of basigin expression and metastasis in mouse melanoma cells. , 2011, Experimental cell research.

[116]  C. Stephan,et al.  Metastamirs: a stepping stone towards improved cancer management , 2011, Nature Reviews Clinical Oncology.

[117]  Yu Huang,et al.  MicroRNA-21 promotes the cell proliferation, invasion and migration abilities in ovarian epithelial carcinomas through inhibiting the expression of PTEN protein. , 2010, International journal of molecular medicine.

[118]  R. Jove,et al.  miR‐194 is a marker of hepatic epithelial cells and suppresses metastasis of liver cancer cells in mice , 2010, Hepatology.

[119]  Jianfang Li,et al.  miR-126 functions as a tumour suppressor in human gastric cancer. , 2010, Cancer letters.

[120]  Diane D. Liu,et al.  miR-200 Inhibits Lung Adenocarcinoma Cell Invasion and Metastasis by Targeting Flt1/VEGFR1 , 2010, Molecular Cancer Research.

[121]  I. Wistuba,et al.  TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs , 2010, Nature.

[122]  Tohru Mochizuki,et al.  Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line , 2010, PloS one.

[123]  Lan Xu,et al.  miR-21 and miR-31 Converge on TIAM1 to Regulate Migration and Invasion of Colon Carcinoma Cells* , 2010, The Journal of Biological Chemistry.

[124]  F. Ferrari,et al.  A MicroRNA Targeting Dicer for Metastasis Control , 2010, Cell.

[125]  Jun S. Song,et al.  Lineage-Specific Transcriptional Regulation of DICER by MITF in Melanocytes , 2010, Cell.

[126]  Guanghai Yang,et al.  MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC). , 2010, Clinica chimica acta; international journal of clinical chemistry.

[127]  C. Croce,et al.  MicroRNA cluster 221-222 and estrogen receptor alpha interactions in breast cancer. , 2010, Journal of the National Cancer Institute.

[128]  Lakshmanane Boominathan The Tumor Suppressors p53, p63, and p73 Are Regulators of MicroRNA Processing Complex , 2010, PloS one.

[129]  S. Peiró,et al.  Snail Family Regulation and Epithelial Mesenchymal Transitions in Breast Cancer Progression , 2010, Journal of Mammary Gland Biology and Neoplasia.

[130]  C. Rogler,et al.  Overexpression of miR-21 Promotes an In vitro Metastatic Phenotype by Targeting the Tumor Suppressor RHOB , 2010, Molecular Cancer Research.

[131]  Y. Mo,et al.  MicroRNA-145 suppresses cell invasion and metastasis by directly targeting mucin 1. , 2010, Cancer research.

[132]  Li Xie,et al.  MicroRNA-21 regulates breast cancer invasion partly by targeting tissue inhibitor of metalloproteinase 3 expression , 2010, Journal of experimental & clinical cancer research : CR.

[133]  Robert A. Weinberg,et al.  Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model , 2010, Nature Biotechnology.

[134]  Frank Speleman,et al.  miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis , 2010, Nature Cell Biology.

[135]  Hansjuerg Alder,et al.  miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation. , 2009, Cancer cell.

[136]  M. Lerch,et al.  Retinoic acid receptor antagonists inhibit miR-10a expression and block metastatic behavior of pancreatic cancer. , 2009, Gastroenterology.

[137]  Keara M. Lane,et al.  Dicer1 functions as a haploinsufficient tumor suppressor. , 2009, Genes & development.

[138]  Sijin Liu,et al.  Inhibition of rho-associated kinase signaling prevents breast cancer metastasis to human bone. , 2009, Cancer research.

[139]  R. Weinberg,et al.  MicroRNAs: Crucial multi-tasking components in the complex circuitry of tumor metastasis , 2009, Cell cycle.

[140]  Min Liu,et al.  MicroRNA‐9 inhibits ovarian cancer cell growth through regulation of NF‐κB1 , 2009, The FEBS journal.

[141]  Stefano Volinia,et al.  MicroRNA expression profiling of human metastatic cancers identifies cancer gene targets , 2009, The Journal of pathology.

[142]  Alexander Pertsemlidis,et al.  Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression. , 2009, Genes & development.

[143]  B. Qian,et al.  High miR-21 expression in breast cancer associated with poor disease-free survival in early stage disease and high TGF-β1 , 2009, Breast Cancer Research and Treatment.

[144]  N. Voirin,et al.  Prognostic value of Dicer expression in human breast cancers and association with the mesenchymal phenotype , 2009, British Journal of Cancer.

[145]  Raghu Kalluri,et al.  EMT: when epithelial cells decide to become mesenchymal-like cells. , 2009, The Journal of clinical investigation.

[146]  Michael T. McManus,et al.  Up-regulation of miR-21 by HER2/neu Signaling Promotes Cell Invasion* , 2009, The Journal of Biological Chemistry.

[147]  Hsien-Da Huang,et al.  MicroRNA‐122, a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma , 2009, Hepatology.

[148]  K. Zatloukal,et al.  miR‐29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis , 2009, EMBO reports.

[149]  Xu-ping Fu,et al.  Global gene expression analysis reveals reduced abundance of putative microRNA targets in human prostate tumours , 2009, BMC Genomics.

[150]  S. Dangi‐Garimella,et al.  Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let‐7 , 2009, The EMBO journal.

[151]  Kedar S Vaidya,et al.  Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis. , 2009, Cancer research.

[152]  C. Bracken,et al.  The role of microRNAs in metastasis and epithelial-mesenchymal transition , 2009, Cellular and Molecular Life Sciences.

[153]  Qiong Shao,et al.  MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis. , 2008, RNA.

[154]  M. F. Shannon,et al.  A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. , 2008, Cancer research.

[155]  S. Ropero,et al.  A microRNA DNA methylation signature for human cancer metastasis , 2008, Proceedings of the National Academy of Sciences.

[156]  T. Wurdinger,et al.  MicroRNA 21 Promotes Glioma Invasion by Targeting Matrix Metalloproteinase Regulators , 2008, Molecular and Cellular Biology.

[157]  M. Korpal,et al.  The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional Repressors ZEB1 and ZEB2* , 2008, Journal of Biological Chemistry.

[158]  T. Brabletz,et al.  A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells , 2008, EMBO reports.

[159]  E. Lander,et al.  Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. , 2008, Cancer research.

[160]  G. Goodall,et al.  The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1 , 2008, Nature Cell Biology.

[161]  G. Daley,et al.  Selective Blockade of MicroRNA Processing by Lin28 , 2008, Science.

[162]  H. Allgayer,et al.  MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer , 2008, Oncogene.

[163]  Sun-Mi Park,et al.  The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. , 2008, Genes & development.

[164]  Shuomin Zhu,et al.  MicroRNA-21 targets tumor suppressor genes in invasion and metastasis , 2008, Cell Research.

[165]  Lin Zhang,et al.  The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis , 2008, Nature Cell Biology.

[166]  W. Gerald,et al.  Endogenous human microRNAs that suppress breast cancer metastasis , 2008, Nature.

[167]  J. Lieberman,et al.  let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells , 2007, Cell.

[168]  A. Albini,et al.  Metastasis signatures: genes regulating tumor–microenvironment interactions predict metastatic behavior , 2007, Cancer and Metastasis Reviews.

[169]  E. Miska,et al.  MicroRNA—implications for cancer , 2007, Virchows Archiv.

[170]  H. Shim,et al.  Blockade of invasion and metastasis of breast cancer cells via targeting CXCR4 with an artificial microRNA. , 2007, Biochemical and biophysical research communications.

[171]  M. Esteller,et al.  CpG island hypermethylation of tumor suppressor microRNAs in human cancer. , 2007, Cell cycle.

[172]  T. Golub,et al.  Impaired microRNA processing enhances cellular transformation and tumorigenesis , 2007, Nature Genetics.

[173]  Shuomin Zhu,et al.  miR-21-mediated tumor growth , 2007, Oncogene.

[174]  G. Carmichael,et al.  ADAR editing wobbles the microRNA world. , 2007, ACS chemical biology.

[175]  Jason H. Moore,et al.  Characterization of microRNA expression levels and their biological correlates in human cancer cell lines. , 2007, Cancer research.

[176]  J. Massagué,et al.  Cancer Metastasis: Building a Framework , 2006, Cell.

[177]  C. Croce,et al.  MicroRNA signatures in human cancers , 2006, Nature Reviews Cancer.

[178]  Rajiv Dhir,et al.  Up-regulation of dicer, a component of the MicroRNA machinery, in prostate adenocarcinoma. , 2006, The American journal of pathology.

[179]  Tushar Patel,et al.  Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. , 2006, Gastroenterology.

[180]  Raghu Kalluri,et al.  The epithelial–mesenchymal transition: new insights in signaling, development, and disease , 2006, The Journal of cell biology.

[181]  C. Croce,et al.  A microRNA expression signature of human solid tumors defines cancer gene targets , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[182]  R. Shiekhattar,et al.  Human RISC Couples MicroRNA Biogenesis and Posttranscriptional Gene Silencing , 2005, Cell.

[183]  G. Maira,et al.  Extensive modulation of a set of microRNAs in primary glioblastoma. , 2005, Biochemical and biophysical research communications.

[184]  K. Kosik,et al.  MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. , 2005, Cancer research.

[185]  H. Horvitz,et al.  MicroRNA expression profiles classify human cancers , 2005, Nature.

[186]  R. Shiekhattar,et al.  The Microprocessor complex mediates the genesis of microRNAs , 2004, Nature.

[187]  Sanghyuk Lee,et al.  MicroRNA genes are transcribed by RNA polymerase II , 2004, The EMBO journal.

[188]  K. Czaplinski,et al.  Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. , 2004, RNA.

[189]  I. Fidler,et al.  The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited , 2003, Nature Reviews Cancer.

[190]  Joey Berlin,et al.  Rude Awakening. , 2016, Texas medicine.

[191]  Junjie Xiao,et al.  MicroRNA Therapeutics. , 2015, Mini reviews in medicinal chemistry.

[192]  Gerry Melinoa,et al.  Loss of p 63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer , 2014 .

[193]  Huaihua Luo,et al.  miR-139 targets CXCR4 and inhibits the proliferation and metastasis of laryngeal squamous carcinoma cells , 2013, Medical Oncology.

[194]  W. Wang,et al.  Regulation of epidermal growth factor receptor signaling by plasmid-based microRNA-7 inhibits human malignant gliomas growth and metastasis in vivo. , 2013, Neoplasma.

[195]  D. Fan,et al.  Regulation of UHRF 1 by miR-146 a / b modulates gastric cancer invasion and metastasis , 2013 .

[196]  Jing Liu,et al.  MicroRNA-21 (miR-21) expression promotes growth, metastasis, and chemo- or radioresistance in non-small cell lung cancer cells by targeting PTEN , 2012, Molecular and Cellular Biochemistry.

[197]  I. Ng,et al.  The microRNA miR-139 suppresses metastasis and progression of hepatocellular carcinoma by down-regulating Rho-kinase 2. , 2011, Gastroenterology.

[198]  C. Croce,et al.  p53 regulates epithelial–mesenchymal transition through microRNAs targeting ZEB1 and ZEB2 , 2011, The Journal of experimental medicine.

[199]  Yusuke Yamamoto,et al.  Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes. , 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

[200]  R. Weinberg,et al.  Tumour invasion and metastasis initiated by microRNA-10b in breast cancer , 2008, Nature.

[201]  H. Osada,et al.  MicroRNAs in biological processes and carcinogenesis. , 2007, Carcinogenesis.