No contribution of angiotensin-converting enzyme (ACE) gene variants to severe obesity: a model for comprehensive case/control and quantitative cladistic analysis of ACE in human diseases

[1]  H. Stefánsson,et al.  Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes , 2006, Nature Genetics.

[2]  Mark I McCarthy,et al.  What makes a good genetic association study? , 2005, The Lancet.

[3]  D. Meyre,et al.  Association of melanin-concentrating hormone receptor 1 5' polymorphism with early-onset extreme obesity. , 2005, Diabetes.

[4]  K. Clément,et al.  Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes , 2005, Nature Genetics.

[5]  U. Kintscher,et al.  PPAR&ggr;-Activating Angiotensin Type-1 Receptor Blockers Induce Adiponectin , 2005 .

[6]  K. Clément,et al.  Hypoadiponectinaemia and high risk of type 2 diabetes are associated with adiponectin-encoding (ACDC) gene promoter variants in morbid obesity: evidence for a role of ACDC in diabesity , 2005, Diabetologia.

[7]  P. Froguel,et al.  The genetics of human obesity , 2005, Nature Reviews Genetics.

[8]  K. Blennow,et al.  A cladistic model of ACE sequence variation with implications for myocardial infarction, Alzheimer disease and obesity. , 2004, Human molecular genetics.

[9]  Kazuya Yamada,et al.  The G/G genotype of a resistin single-nucleotide polymorphism at -420 increases type 2 diabetes mellitus susceptibility by inducing promoter activity through specific binding of Sp1/3. , 2004, American journal of human genetics.

[10]  K. Shimamoto,et al.  Blockade of the renin-angiotensin system decreases adipocyte size with improvement in insulin sensitivity. , 2004, Journal of hypertension.

[11]  A. Scheen VALUE: analysis of results , 2004, The Lancet.

[12]  J. Staessen,et al.  VALUE: analysis of results , 2004, The Lancet.

[13]  P. Czernichow,et al.  Adult Height Distribution in Subjects Born Small for Gestational Age , 2004, Hormone Research in Paediatrics.

[14]  K. Clément,et al.  Genome-wide linkage analysis for severe obesity in french caucasians finds significant susceptibility locus on chromosome 19q. , 2004, Diabetes.

[15]  J. Flier,et al.  Adipose Tissue as an Endocrine Organ , 2014 .

[16]  U. Kintscher,et al.  Angiotensin Type 1 Receptor Blockers Induce Peroxisome Proliferator–Activated Receptor-γ Activity , 2004, Circulation.

[17]  Peter Donnelly,et al.  A comparison of bayesian methods for haplotype reconstruction from population genotype data. , 2003, American journal of human genetics.

[18]  Michael J Thun,et al.  Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. , 2003, The New England journal of medicine.

[19]  F. Cappuccio,et al.  Genetic Variation in the ReninAngiotensin System and Abdominal Adiposity in Men: The Olivetti Prospective Heart Study , 2003, Annals of Internal Medicine.

[20]  I. Gut,et al.  Genotyping single-nucleotide polymorphisms by matrix-assisted laser-desorption/ionization time-of-flight mass spectrometry. , 2002, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[21]  Arya M. Sharma,et al.  Angiotensin blockade prevents type 2 diabetes by formation of fat cells. , 2002, Hypertension.

[22]  A. Adeyemo,et al.  Angiotensin-1-converting enzyme (ACE) plasma concentration is influenced by multiple ACE-linked quantitative trait nucleotides. , 2002, Human molecular genetics.

[23]  K. Flegal,et al.  Prevalence and trends in obesity among US adults, 1999-2000. , 2002, JAMA.

[24]  R C Elston,et al.  Linkage and association analysis of angiotensin I-converting enzyme (ACE)-gene polymorphisms with ACE concentration and blood pressure. , 2001, American journal of human genetics.

[25]  M. Rieder,et al.  Localization of a small genomic region associated with elevated ACE. , 2000, American journal of human genetics.

[26]  G. Abecasis,et al.  Pedigree tests of transmission disequilibrium , 2000, European Journal of Human Genetics.

[27]  Gonçalo R. Abecasis,et al.  GOLD-Graphical Overview of Linkage Disequilibrium , 2000, Bioinform..

[28]  G. Lathrop,et al.  Fine-mapping of an ancestral recombination breakpoint in DCP1 , 1999, Nature Genetics.

[29]  G. Colditz,et al.  The disease burden associated with overweight and obesity. , 1999, JAMA.

[30]  M. Rieder,et al.  Sequence variation in the human angiotensin converting enzyme , 1999, Nature Genetics.

[31]  M Farrall,et al.  Measured haplotype analysis of the angiotensin-I converting enzyme gene. , 1998, Human molecular genetics.

[32]  P Galan,et al.  A primary prevention trial using nutritional doses of antioxidant vitamins and minerals in cardiovascular diseases and cancers in a general population: the SU.VI.MAX study--design, methods, and participant characteristics. SUpplementation en VItamines et Minéraux AntioXydants. , 1998, Controlled clinical trials.

[33]  Jimmy D Bell,et al.  Human gene for physical performance , 1998, Nature.

[34]  L. Peltonen,et al.  The deltaccr5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in Northeastern Europe. , 1998, Human molecular genetics.

[35]  W. Ewens,et al.  A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test. , 1998, American journal of human genetics.

[36]  H. Schunkert Polymorphism of the angiotensin-converting enzyme gene and cardiovascular disease , 1997, Journal of Molecular Medicine.

[37]  L Lafay,et al.  Determinants and nature of dietary underreporting in a free-living population: the Fleurbaix Laventie Ville Santé (FLVS) study , 1997, International Journal of Obesity.

[38]  J. W. Taylor,et al.  Angiotensinogen gene expression in adipose tissue: analysis of obese models and hormonal and nutritional control. , 1997, The American journal of physiology.

[39]  B. H. Jones,et al.  Angiotensin II increases lipogenesis in 3T3-L1 and human adipose cells. , 1997, Endocrinology.

[40]  L. Tiret,et al.  Identification of new polymorphisms of the angiotensin I-converting enzyme (ACE) gene, and study of their relationship to plasma ACE levels by two-QTL segregation-linkage analysis. , 1996, American journal of human genetics.

[41]  John A. Todd,et al.  Towards fully automated genome–wide polymorphism screening , 1995, Nature Genetics.

[42]  C. Darimont,et al.  Differentiation of preadipose cells: paracrine role of prostacyclin upon stimulation of adipose cells by angiotensin-II. , 1994, Endocrinology.

[43]  Philippe Amouyel,et al.  Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction , 1992, Nature.

[44]  P Corvol,et al.  An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. , 1990, The Journal of clinical investigation.

[45]  U. Kintscher,et al.  PPARgamma-activating angiotensin type-1 receptor blockers induce adiponectin. , 2005, Hypertension.

[46]  Pak Chung Sham,et al.  Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits , 2003, Bioinform..

[47]  G. Abecasis,et al.  A general test of association for quantitative traits in nuclear families. , 2000, American journal of human genetics.

[48]  M. Owen,et al.  Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease , 1999, Nature Genetics.