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Topoisomerase I inhibitor, irinotecan, depletes regulatory T cells and up-regulates MHC class I and PD-L1 expression, resulting in a supra-additive antitumor effect when combined with anti-PD-L1 antibodies
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T. Iwai
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D. Wakita
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Masamichi Sugimoto
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K. Yorozu
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M. Kurasawa
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Kaname Yamamoto
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