Optimisation of the inactivated vaccine dose against heartwater and in vitro quantification of Ehrlichia ruminantium challenge material.

[1]  P. Alves,et al.  Process development for the mass production of Ehrlichia ruminantium. , 2006, Vaccine.

[2]  P. Alves,et al.  Quantification of Ehrlichia ruminantium by real time PCR. , 2005, Veterinary microbiology.

[3]  B. Allsopp,et al.  An attenuated Ehrlichia ruminantium (Welgevonden stock) vaccine protects small ruminants against virulent heartwater challenge. , 2005, Vaccine.

[4]  N. Vachiéry,et al.  Nested PCR for Detection and Genotyping of Ehrlichia ruminantium: Use in Genetic Diversity Analysis , 2004, Annals of the New York Academy of Sciences.

[5]  N. Vachiéry,et al.  Protective killed Ehrlichia ruminantium vaccine elicits IFN-gamma responses by CD4+ and CD8+ T lymphocytes in goats. , 2004, Veterinary immunology and immunopathology.

[6]  N. Vachiéry,et al.  Analysis of Ehrlichia ruminantium‐specific T1/T2 responses during vaccination with a protective killed vaccine and challenge of goats , 2004, Parasite immunology.

[7]  K. Brayton,et al.  Development of Improved Vaccines for Heartwater , 2003, Annals of the New York Academy of Sciences.

[8]  K. Brayton,et al.  Preparation of Ehrlichia ruminantium challenge material for quantifiable and reproducible challenge in mice and sheep. , 2003, Veterinary parasitology.

[9]  P. Braga,et al.  Flow Cytometric Assessment of Susceptibilities of Streptococcus pyogenes to Erythromycin and Rokitamycin , 2003, Antimicrobial Agents and Chemotherapy.

[10]  D. Martinez,et al.  IFN‐γ As an Indicator of Successful Immunization of Goats Vaccinated with a Killed Cowdria ruminantium Vaccine , 2002, Annals of the New York Academy of Sciences.

[11]  G. Smith,et al.  Reduction in mortality from heartwater in cattle, sheep and goats exposed to field challenge using an inactivated vaccine. , 2001, Veterinary parasitology.

[12]  A. Barbet,et al.  The inactivated Cowdria ruminantium vaccine for heartwater protects against heterologous strains and against laboratory and field tick challenge. , 1998, Vaccine.

[13]  D. McKeever,et al.  Immunization of Cattle by Infection withCowdria ruminantium Elicits T Lymphocytes That Recognize Autologous, Infected Endothelial Cells and Monocytes , 1998, Infection and Immunity.

[14]  D. McKeever,et al.  Analysis of T-cell responses in cattle immunized against heartwater by vaccination with killed elementary bodies of Cowdria ruminantium , 1997, Infection and immunity.

[15]  D. Martinez,et al.  Comparative efficacy of Freund's and Montanide ISA50 adjuvants for the immunisation of goats against heartwater with inactivated Cowdria ruminantium. , 1996, Veterinary parasitology.

[16]  N. Vachiéry,et al.  Recombinant bovine interferon gamma inhibits the growth of Cowdria ruminantium but fails to induce major histocompatibility complex class II following infection of endothelial cells. , 1996, Veterinary immunology and immunopathology.

[17]  G. Reddy,et al.  Sequence heterogeneity of the major antigenic protein 1 genes from Cowdria ruminantium isolates from different geographical areas , 1996, Clinical and diagnostic laboratory immunology.

[18]  M. Sileghem,et al.  Neutralization of bovine Concanavalin‐A T cell supernatant‐mediated anti‐Cowdria ruminantium activity with antibodies specific to Interferon gamma but not to tumor necrosis factor , 1996, Parasite immunology.

[19]  D. Martinez,et al.  Protection of goats against heartwater acquired by immunisation with inactivated elementary bodies of Cowdria ruminantium. , 1994, Veterinary immunology and immunopathology.

[20]  G. Smith,et al.  Conconavalin A-stimulated bovine T-cell supernatants inhibit growth of Cowdria ruminantium in bovine endothelial cells in vitro , 1994, Infection and immunity.

[21]  F. Jongejan,et al.  Vaccination against heartwater using in vitro attenuated Cowdria ruminantium organisms. , 1993, Revue d'elevage et de medecine veterinaire des pays tropicaux.

[22]  F. Jongejan.  Protective immunity to heartwater (Cowdria ruminantium infection) is acquired after vaccination with in vitro-attenuated rickettsiae , 1991, Infection and immunity.

[23]  D. Martinez,et al.  [Comparison between 3 antigens for the serodiagnosis of heartwater disease by indirect immunofluorescence]. , 1990, Revue d'Elevage et de Médecine Vétérinaire des Pays Tropicaux.

[24]  J. Olivier,et al.  The heterogenicity of Cowdria ruminantium stocks: cross-immunity and serology in sheep and pathogenicity to mice. , 1989, The Onderstepoort journal of veterinary research.

[25]  I. G. Wright.  Veterinary Protozoan and Hemoparasite Vaccines , 1989 .

[26]  J. Bezuidenhout,et al.  The historical background and global importance of heartwater. , 1987, The Onderstepoort journal of veterinary research.

[27]  N. Barré,et al.  Danger of introducing heartwater onto the American mainland: potential role of indigenous and exotic Amblyomma ticks. , 1987, The Onderstepoort journal of veterinary research.

[28]  J. Plessis.  A METHOD FOR DETERMINING THE COWDRIA RUMINANTIUM INFECTION RATE OF AMBLYOMMA HEBRAEUM: EFFECTS IN MICE INJECTED WITH TICK HOMOGENATES , 1985 .

[29]  N. Barré,et al.  Quelques observations sur une souche de Cowdria ruminantium isolée en Guadeloupe (Antilles françaises) , 1985 .

[30]  N. Barré,et al.  Existence de la cowdriose (heartwater) à Cowdria ruminantium chez les ruminants des Antilles françaises (La Guadeloupe) et des Mascareignes (La Réunion et Ile Maurice) , 1980 .

[31]  J. C. Snyder,et al.  THE INFLUENCE OF CERTAIN SALTS, AMINO ACIDS, SUGARS, AND PROTEINS ON THE STABILITY OF RICKETTSIAE , 1950, Journal of bacteriology.