Somatic Mutations in Epidermal Growth Factor Receptor Signaling Pathway Genes in Non-small Cell Lung Cancers
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H. Jeon | T. Jung | E. Lee | G. Jin | Shin‐Yup Lee | M. Kim | J. Choi | S. Cha | Sukki Cho | T. Park | S. Yoo | Ji Young Park | Jae-Yong Park | C. Kim
[1] Dong Sun Kim,et al. PTEN mutations and relationship to EGFR, ERBB2, KRAS, and TP53 mutations in non-small cell lung cancers. , 2010, Lung cancer.
[2] Chang Ho Kim,et al. TP53 Mutations in Korean Patients with Non-small Cell Lung Cancer , 2010, Journal of Korean medical science.
[3] J. Park,et al. LKB1 mutations are extremely rare in Korean non-small cell lung cancers. , 2010, Cancer genetics and cytogenetics.
[4] Jun Yokota,et al. A gene‐alteration profile of human lung cancer cell lines , 2009, Human mutation.
[5] L. Tanoue,et al. The new lung cancer staging system. , 2009, Chest.
[6] M. Meyerson,et al. PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR. , 2009, Cancer research.
[7] Michael Peyton,et al. Alterations in Genes of the EGFR Signaling Pathway and Their Relationship to EGFR Tyrosine Kinase Inhibitor Sensitivity in Lung Cancer Cell Lines , 2009, PloS one.
[8] A. Lièvre,et al. Mutations and Response to Epidermal Growth Factor Receptor Inhibitors , 2009, Clinical Cancer Research.
[9] S. Baker,et al. PTEN and the PI3-kinase pathway in cancer. , 2009, Annual review of pathology.
[10] Brian H. Dunford-Shore,et al. Somatic mutations affect key pathways in lung adenocarcinoma , 2008, Nature.
[11] W. Lam,et al. PIK3CA mutations and copy number gains in human lung cancers. , 2008, Cancer research.
[12] M. Meyerson,et al. Mutations in the LKB1 tumour suppressor are frequently detected in tumours from Caucasian but not Asian lung cancer patients , 2008, British Journal of Cancer.
[13] Chih‐Hsin Yang. EGFR tyrosine kinase inhibitors for the treatment of NSCLC in East Asia: present and future. , 2008, Lung cancer.
[14] M. Moasser,et al. The epidermal growth factor receptor family: Biology driving targeted therapeutics , 2008, Cellular and Molecular Life Sciences.
[15] Y. Yatabe,et al. LKB1 gene mutations in Japanese lung cancer patients , 2007, Cancer science.
[16] Roy S Herbst,et al. KRAS Mutation Is an Important Predictor of Resistance to Therapy with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non–Small-Cell Lung Cancer , 2007, Clinical Cancer Research.
[17] Daniel A. Haber,et al. Epidermal growth factor receptor mutations in lung cancer , 2007, Nature Reviews Cancer.
[18] J. Park,et al. EGFR, ERBB2, and KRAS mutations in Korean non-small cell lung cancer patients. , 2007, Cancer genetics and cytogenetics.
[19] H. Sasaki,et al. PIK3CA mutation status in Japanese lung cancer patients. , 2006, Lung cancer.
[20] Y. Bang,et al. Optimization of Patient Selection for Gefitinib in Non–Small Cell Lung Cancer by Combined Analysis of Epidermal Growth Factor Receptor Mutation, K-ras Mutation, and Akt Phosphorylation , 2006, Clinical Cancer Research.
[21] W. Park,et al. Somatic mutations of the ERBB4 kinase domain in human cancers , 2006, International journal of cancer.
[22] J. Minna,et al. Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. , 2006, Journal of the National Cancer Institute.
[23] A. Gazdar,et al. Somatic mutations of epidermal growth factor receptor signaling pathway in lung cancers , 2006, International journal of cancer.
[24] J. Minna,et al. Clinicopathologic Significance of the Mutations of the Epidermal Growth Factor Receptor Gene in Patients with Non–Small Cell Lung Cancer , 2005, Clinical Cancer Research.
[25] M. Beeram,et al. Raf: a strategic target for therapeutic development against cancer. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[26] Elisa Rossi,et al. Increased HER2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor-positive non-small-cell lung cancer patients. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[27] K. Aldape,et al. PTEN expression in non-small-cell lung cancer: evaluating its relation to tumor characteristics, allelic loss, and epigenetic alteration. , 2005, Human pathology.
[28] J. Minna,et al. Somatic mutations of the HER2 kinase domain in lung adenocarcinomas. , 2005, Cancer research.
[29] H. Varmus,et al. KRAS Mutations and Primary Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib , 2005, PLoS medicine.
[30] Takayuki Kosaka,et al. Mutations of the Epidermal Growth Factor Receptor Gene in Lung Cancer , 2004, Cancer Research.
[31] S. Gabriel,et al. EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy , 2004, Science.
[32] Patricia L. Harris,et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. , 2004, The New England journal of medicine.
[33] J. Ptak,et al. High Frequency of Mutations of the PIK3CA Gene in Human Cancers , 2004, Science.
[34] E. Rowinsky. The erbB family: targets for therapeutic development against cancer and therapeutic strategies using monoclonal antibodies and tyrosine kinase inhibitors. , 2004, Annual review of medicine.
[35] J. Minna,et al. Loss of heterozygosity of chromosome 12p does not correlate with KRAS mutation in non‐small cell lung cancer , 2003, International journal of cancer.
[36] A. Nicholson,et al. Mutations of the BRAF gene in human cancer , 2002, Nature.
[37] Li Mao,et al. Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation. , 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.
[38] W. Travis,et al. The new World Health Organization classification of lung tumours , 2001, European Respiratory Journal.
[39] Y. Yarden,et al. Untangling the ErbB signalling network , 2001, Nature Reviews Molecular Cell Biology.
[40] J. Yokota,et al. Inactivation of the PTEN/MMAC1/TEP1 gene in human lung cancers , 1998, Genes, chromosomes & cancer.
[41] C. Harris,et al. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. , 1994, Cancer research.
[42] J. Minna,et al. Molecular genetics of lung cancer. , 1988, Annual review of medicine.
[43] G. Viglietto,et al. Activating E17K mutation in the gene encoding the protein kinase AKT1 in a subset of squamous cell carcinoma of the lung. , 2008, Cell cycle.