Antiviral properties of ent‐labdene diterpenes of Andrographis paniculata nees, inhibitors of herpes simplex virus type 1

Andrographolide, neoandrographolide and 14‐deoxy‐11,12‐didehydroandrographolide, ent‐labdene diterpenes isolated from Andrographis paniculata showed viricidal activity against herpes simplex virus 1 (HSV‐1). None of these compounds exhibited significant cytotoxicity at viricidal concentrations. Copyright © 2005 John Wiley & Sons, Ltd.

[1]  Kevin M. Smith,et al.  Dehydroandrographolide Succinic Acid Monoester as an Inhibitor against the Human Immunodeficiency Virus , 1991, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.