Current Perspectives on Mycosynthesis of Nanoparticles and Their Biomedical application

Abstract This work is an approach to summarize the overview of the role of nanotechnology with respect to drug discovery program, offering a vast variety of biological research and medical applications, at the cellular and molecular level. The present trends go with the green nanotechnology, as an easy, efficient, and environmental-friendly approach, taking less time and energy for producing safer products and by-products. The other available methods consume more time and energy, and the use of toxic reducing and stabilizing agents makes the products harmful. One of the sources for biosynthesis of nanoparticles (NPs) is fungi that possess wide range of metabolic capabilities, by secreting biomolecules as reducing agents. The green synthesis using fungi can be fully controlled for cultivation and for further bioconversion to obtain desired NPs. This article provides information on myco-based amalgamation of NPs, mechanism of synthesis, and their biomedical application, using fungi as nano-biofactories, an innovative green nanotechnology, that holds tremendous scientific benefits in future applications, such as diagnosis of diseases, treatment of infectious diseases, biolabeling, biosensors, and also for the coating of medical devices.

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