Measurement of Electrical Characteristics of Female Breast Tissues for the Development of the Breast Cancer Detector

In this paper, dielectric characteristics of female breast tissues were measured. Breast Tissues were mainly composed of fat, flbro-glandular and tumor. Measured tissues were directly extracted from mice and a rat just before the measurements to maintain the tissues as fresh as living ones before degeneration. This makes the measured results more accurate. Because the extracted tissues were very thin, they were measured by two methods using HP probe and a newly designed two-port sample holder. Numerical results for the two- port sample holder were obtained for both the forward and inverse problems. Dielectric properties of breast tissues were measured in the frequency range between 50MHz and 5GHz. We calculated the electrical constant with the measured data from the two-port sample holder. As a result of the measurement, the dispersion characteristics of the female breast tissues were fltted into the flrst Cole-Cole model.

[1]  David Djajaputra,et al.  RF / Microwave Interaction with Biological Tissues , 2006 .

[2]  B. McLaughlin,et al.  Miniature open-ended coaxial probes for dielectric spectroscopy applications , 2007 .

[3]  D. K. Misra,et al.  A Quasi-Static Analysis of Open-Ended Coaxial Lines (Short Paper) , 1987 .

[4]  Yifan Chen,et al.  Feasibility Study of Lesion Classification via Contrast-Agent-Aided UWB Breast Imaging , 2010, IEEE Transactions on Biomedical Engineering.

[5]  Stuchly,et al.  Dielectric properties of breast carcinoma and the surrounding tissues , 1988, IEEE Transactions on Biomedical Engineering.

[6]  C. H. Durney,et al.  Microwave Reflection and Transmission Measurements for Pulmonary Diagnosis and Monitoring , 1978, IEEE Transactions on Biomedical Engineering.

[7]  A. A. Pistolkors,et al.  Theory of the Circular Diffraction Antenna , 1948, Proceedings of the IRE.

[8]  K. Foster,et al.  Dielectric properties of tumor and normal tissues at radio through microwave frequencies. , 1981, The Journal of microwave power.

[9]  C. Gabriel The Dielectric Properties of Tissues , 2000 .

[10]  K. Paulsen,et al.  Initial clinical experience with microwave breast imaging in women with normal mammography. , 2007, Academic radiology.

[11]  R. D. Pollard,et al.  An improved technique for permittivity measurements using a coaxial probe , 1997 .

[12]  R. G. Bosisio,et al.  Some calculation methods and universal diagrams for measurement of dielectric constants using open-ended coaxial probes , 1991 .

[13]  W. Joines,et al.  The measured electrical properties of normal and malignant human tissues from 50 to 900 MHz. , 1994, Medical physics.

[14]  Xu Li,et al.  Toward Carbon-Nanotube-Based Theranostic Agents for Microwave Detection and Treatment of Breast Cancer: Enhanced Dielectric and Heating Response of Tissue-Mimicking Materials , 2010, IEEE Transactions on Biomedical Engineering.

[15]  M. D. Janezic,et al.  Analysis of a two-port flanged coaxial holder for shielding effectiveness and dielectric measurements of thin films and thin materials , 1996 .