Infrared and Raman spectroscopic imaging

Preface PART I: Basic Methodology INFRARED AND RAMAN INSTRUMENTATION FOR MAPPING AND IMAGING Introduction to Mapping and Imaging Mid-Infrared Microspectroscopy and Mapping Raman Microspectroscopy and Mapping Near-Infrared Hyperspectral Imaging Raman Hyperspectral Imaging Mid-Infrared Hyperspectral Imaging Mapping with Pulsed Terahertz Radiation Summary CHEMOMETRIC TOOLS FOR IMAGE ANALYSIS Introduction Hyperspectral Images: The Measurement Image Preprocessing Exploratory Image Analysis Quantitative Image Information: Multivariate Image Regression (MIR) Image Segmentation Image Resolution Future Trends PART II: Biomedical Applications VIBRATIONAL SPECTROSCOPIC IMAGING OF SOFT TISSUE Introduction Preparation of Soft Tissue for Vibrational Spectroscopic Imaging Applications to Soft Tissue Conclusions VIBRATIONAL SPECTROSCOPIC ANALYSIS OF HARD TISSUES Introduction Importance of Tissue Age versus Specimen Age FT-IR Spectroscopy Raman Spectroscopy Clinical Applications of Raman Spectroscopy MEDICAL APPLICATIONS OF INFRARED SPECTRAL IMAGING OF INDIVIDUAL CELLS Introduction Methods Results and Discussion Future Potential of SCP/Conclusions PART III: Agriculture, Plants, and Food INFRARED AND RAMAN SPECTROSCOPIC MAPPING AND IMAGING OF PLANT MATERIALS Introduction, Background, and Perspective Application of Mapping and Imaging to Horticultural Crops Application of Mapping and Imaging to Agricultural Crops Mapping and Imaging of Wild Plants and Trees Application of Mapping and Imaging to Algae Interaction Between Plant Tissue and Plant Pathogens NIR HYPERSPECTRAL IMAGING FOR FOOD AND AGRICULTURAL PRODUCTS Introduction HSI as a "Super" NIR Analyzer NIR HS Imager as a "Super" Vision System Conclusion PART IV: Polymers and Pharmaceuticals FT-IR AND NIR SPECTROSCOPIC IMAGING: PRINCIPLES, PRACTICAL ASPECTS, AND APPLICATIONS IN MATERIAL AND PHARMACEUTICAL SCIENCE Introduction Instrumentation for NIR and FT-IR Imaging Applications of FT-IR and FT-NIR Imaging for Polymer Characterization NIR Imaging Spectroscopy for Quality Control of Pharmaceutical Drug Formulations FT-IR Spectroscopic Imaging of Inorganic Materials FT-IR IMAGING IN ATR AND TRANSMISSION MODES: PRACTCAL CONSIDERATIONS AND EMERGING APPLICATIONS FT-IR Imaging: Introduction FT-IR Imaging: Technical Considerations Practical Applications Conclusion and Outlook TERAHERTZ IMAGING OF DRUG PRODUCTS Introduction Low Wavenumber Region in the Infrared Spectrum THz-TDS Technology and Applications THz Imaging in the Pharmaceutical Industry Going Forward Competition versus Cost: A Challenge for the Future Conclusion PART V: Imaging Beyond the Diffraction Limit SPECTROSCOPIC IMAGING OF BIOLOGICAL SAMPLES USING NEAR-FIELD METHODS Tip-Enhanced Raman Scattering (TERS) Detection of Biomolecules Biopolymers Membranes, Viruses, and Bacteria Conclusion INFRARED MAPPING BELOW THE DIFFRACTION LIMIT Introduction and Description of Early Work Near-Field Microscopy by Elastic Scattering from a Tip PART VI: Developments in Methodology SUBSURFACE RAMAN SPECTROSCOPY IN TURBID MEDIA Introduction Techniques for Deep Noninvasive Raman Spectroscopy Examples of Application Areas Conclusions NONLINEAR VIBRATIONAL SPECTROSCOPIC MICROSCOPY OF CELLS AND TISSUE Introduction Principles of Nonlinear Optical Imaging Instrumentation for Multimodal Nonlinear Microscopy Applications WIDEFIELD FT-IR 2D AND 3D IMAGING AT THE MICROSCALE USING SYNCHROTRON RADIATION Introduction Optical Evaluation Mathematical Evaluation of Hyperspectral Cubes Widefield versus Raster Scanning Geometries Examples Conclusions Index