Aschoff bodies in left auricular appendages of patients with mitral stenosis; clinicopathologic study, including postoperative follow-up.

IN RECENT years surgical valvulotomy for mitral stenosis has made it possible to examine microscopically the left auricular appendage and observe histologically the rheumatic process in a part of the heart during life. Since this is a phase in the natural history of rheumatic fever, it may be possible to correlate the incidence and degree of activity with the clinical events of rheumatic cardiac disease. Although the lesions of rheumatic fever have been described in the left auricle proper,* the auricular appendage has escaped more critical examination. Von Glahn, 8 in a study of rheumatic auricular endocarditis, concluded that the changes observed may extend into the first portion of the auricular appendage. He did not, however, record Aschoff bodies in this location. Similarly, Gross, 9 in an exhaustive review of rheumatic auricular lesions, made no reference to the auricular appendage. Unusual circumstances have on occasion prompted the making of sections of this

[1]  B. Castleman,et al.  The significance of Aschoff bodies in the left atrial appendage; a comparison of 40 biopsies removed during mitral commissurotomy with autopsy material from 40 patients dying with fulminating rheumatic fever. , 1953, The New England journal of medicine.

[2]  F. McKeown.  THE LEFT AURICULAR APPENDAGE IN MITRAL STENOSIS , 1953, British heart journal.

[3]  R. P. Glover,et al.  A Journal of the American Heart Association Reactivation of Rheumatic Fever Following Mitral Commissurotomy , 2022 .

[4]  Marvin Kuschneh,et al.  CORRELATION BETWEEN ACTIVE RHEUMATIC LESIONS IN THE LEFT AURICULAR APPENDAGE AND ELSEWHERE IN THE HEART , 1953, The American journal of the medical sciences.

[5]  D. Harken,et al.  Rheumatic "Activity" as Judged by the Presence of Aschoff Bodies in Auricular Appendages of Patients with Mitral Stenosis: II. Clinical Aspects , 1953, Circulation.

[6]  J. P. Decker,et al.  Rheumatic "Activity" as Judged by the Presence of Aschoff Bodies in Auricular Appendages of Patients with Mitral Stenosis: I. Anatomic Aspects , 1953, Circulation.

[7]  J. Enticknap.  BIOPSY OF THE LEFT AURICLE IN MITRAL STENOSIS , 1953, British heart journal.

[8]  Sabiston Dc,et al.  Lesions in auricular appendages removed at operations for mitral stenosis of presumed rheumatic origin. , 1952 .

[9]  S. Winblad,et al.  Studies in mitral stenosis. II. Observations on incidence of active rheumatic carditis in left auricular appendages resected at operation for mitral stenosis. , 1952, American heart journal.

[10]  M. I. Ferrer,et al.  Rheumatic carditis in surgically removed auricular appendages. , 1952, American heart journal.

[11]  R. A. Bloomfield,et al.  STUDIES IN MITRAL STENOSIS: I. A Correlation of Physiologic and Clinical Findings , 1951 .

[12]  C. E. Kossmann,et al.  Rheumatic heart disease in patients over sixty years of age. , 1951, Journal of the American Medical Association.

[13]  F. Wróblewski,et al.  Active rheumatic carditis in patients over 40 years of age. , 1950, American Heart Journal.

[14]  P. Kaufman,et al.  Studies on the aging heart; the pattern of rheumatic heart disease in old age (a clinical pathological study). , 1950, Annals of Internal Medicine.

[15]  H. Cookson.  MITRAL STENOSIS IN LATER LIFE , 1949, British heart journal.

[16]  E. M. Hall,et al.  The incidence of rheumatic stigmas in hearts which are usually considered nonrheumatic , 1943 .

[17]  C. E. Kossmann,et al.  Auricular fibrillation of long duration in rheumatic heart disease , 1942 .

[18]  L. Gross.  Lesions of the Left Auricle in Rheumatic Fever. , 1935, The American journal of pathology.

[19]  W. C. Vonglahn.  Auricular Endocarditis of Rheumatic Origin. , 1926, The American journal of pathology.

[20]  René Théophile Hyacinthe Laennec.  De l'auscultation médiate, ou, Traité du diagnostic des maladies des poumons et du coeur : fondé principalement sur ce nouveau moyen d'exploration , 1819 .