Letter to the Editor: Response to Manzano Surroca et al. "Poland Sequence: Retrospective Analysis of 66 Cases." Annals of Plastic Surgery, May 2019.

Sir: M omeni et al conclude that breast reconstruction using abdominal free flaps can cause venous stasis, increasing the risk of deep venous thrombosis (DVT). Surprisingly, the authors do not report their actual data but rather percent changes of the (presumably) means, represented on a single illustration with an unlabeled horizontal axis. The average length of hospitalization, and therefore timing of the last scan, is not provided. There was no control group. The error bars are remarkably tight and uniform, with wide spacing that suggests highly significant and consistent changes. Substantial variability is known to affect repeated ultrasound measurements of the common femoral vein diameter and blood velocity. All patients received chemoprophylaxis, differing from recent recommendations. One patient developed a pulmonary embolism (3.3%) 10 days postoperatively, evidently from an undetected DVT. The authors report a 19.1% dilation of the left common femoral vein and a 10.9% reduction in maximal flow velocity on the day after surgery. These changes were almost identical on the date of discharge from hospital. It is difficult to reconcile the percent change in the lumen diameter with the percent change in velocity. For a constant flow rate (in cubic centimeters per second), the blood velocity should decrease inversely proportionally with the square of the vessel diameter (1/r). A 19.1% increase in diameter should produce a 29.5% reduction in velocity. However, the authors report a reduction in velocity of only 10.9%. If the data are correct, the blood volume flowing into and out of the lower extremity must increase 26% and remain elevated on the date of discharge, requiring a 26% increase in cardiac output. This change could be achieved by sustained tachycardia, yet (fortunately) none is reported. The authors believe that repair of the abdominal muscle fascia impedes venous return

[1]  E. Swanson Prospective Study of Doppler Ultrasound Surveillance for Deep Venous Thromboses in 1000 Plastic Surgery Outpatients. , 2020, Plastic and reconstructive surgery.

[2]  Chih-hung Lin,et al.  Attitudes of Hand Surgeons and Hand Reconstruction Patients Toward Hand Allotransplantation in Taiwan. , 2020, Annals of plastic surgery.

[3]  M. Crimi,et al.  Experiences of patients with Poland syndrome of diagnosis and care in Italy: a pilot survey , 2019, Orphanet Journal of Rare Diseases.

[4]  C. Pannucci,et al.  Breast Reconstruction with Free Abdominal Flaps Is Associated with Persistent Lower Extremity Venous Stasis. , 2019, Plastic and reconstructive surgery.

[5]  Y. Zhuang,et al.  Breast Reconstruction in Poland Syndrome Patients with Latissimus Dorsi Myo Flap and Implant: An Efficient Endoscopic Approach Using Single Transverse Axillary Incision , 2019, Aesthetic Plastic Surgery.

[6]  T. Damsgaard,et al.  A Systematic Review and Meta-analysis of Functional Shoulder Impairment After Latissimus Dorsi Breast Reconstruction , 2019, Annals of plastic surgery.

[7]  X. Tarrado,et al.  Poland Sequence: Retrospective Analysis of 66 Cases. , 2019, Annals of plastic surgery.

[8]  M. Valle,et al.  Poland syndrome: A proposed classification system and perspectives on diagnosis and treatment. , 2018, Seminars in pediatric surgery.

[9]  F. de Stefano,et al.  Self-determination, healthcare treatment and minors in Italian clinical practice: ethical, psychological, juridical and medical-legal profiles , 2018, Acta bio-medica : Atenei Parmensis.

[10]  D. Merlo,et al.  Body Image Disorders and Surgical Timing in Patients Affected by Poland Syndrome: Data Analysis of 58 Case Studies , 2016, Plastic and reconstructive surgery.

[11]  S. Ariyan,et al.  Benefits and Risks of Prophylaxis for Deep Venous Thrombosis and Pulmonary Embolus in Plastic Surgery: A Systematic Review and Meta-Analysis of Controlled Trials and Consensus Conference , 2016, Plastic and reconstructive surgery.

[12]  Subhas C. Gupta,et al.  Increased Intraabdominal Pressure in Abdominoplasty: Delineation of Risk Factors , 2007, Plastic and reconstructive surgery.

[13]  R. Langer,et al.  Common femoral vein dimensions and hemodynamics including Valsalva response as a function of sex, age, and ethnicity in a population study. , 2001, Journal of vascular surgery.

[14]  H. Anderl,et al.  Early correction of the thoracic deformity of Poland's syndrome in children with the latissimus dorsi muscle flap: long term follow-up of two cases. , 1986, British journal of plastic surgery.