Effects associated with Permeability Changes caused by Gramicidin A in Electroplax Membrane

In the membrane of the electroplax from the electric organ of Electrophorus electricus, gramicidin A causes an increase of permeability to sodium ions. Cooperative effects are associated with the development of this long lasting change in permeability.

[1]  H. Grundfest,et al.  Analysis of Spike Electrogenesis and Depolarizing K Inactivation in Electroplaques of Electrophorus electricus, L , 1965, The Journal of general physiology.

[2]  D. O. Rudin,et al.  Action Potentials induced in Biomolecular Lipid Membranes , 1968, Nature.

[3]  J. Dunitz,et al.  Structure of the K+ complex with nonactin, a macrotetrolide antibiotic possessing highly specific K+ transport properties. , 1967, Journal of molecular biology.

[4]  J. Changeux,et al.  On the mode of action of colicins: a model of regulation at the membrane level. , 1967, Journal of theoretical biology.

[5]  J. Changeux,et al.  On the excitability and cooperativity of the electroplax membrane. , 1968, Proceedings of the National Academy of Sciences of the United States of America.

[6]  J. Changeux,et al.  Affinity labeling of the acetylcholine-receptor. , 1967, Proceedings of the National Academy of Sciences of the United States of America.

[7]  L. Mullins,et al.  Molecular structure and functional activity of nerve cells , 1956 .

[8]  A. Karlin,et al.  Effects of blocking sulfhydryl groups and of reducing disulfide bonds on the acetylcholine-activated permeability system of the electroplax. , 1966, Biochimica et biophysica acta.

[9]  H. Morawetz.  Macromolecules in solution , 1965 .

[10]  D. Nachmansohn.  Chemical and molecular basis of nerve activity , 1959 .

[11]  M. M. Shemyakin,et al.  The physicochemical basis of the functioning of biological membranes: conformational specificity of the interaction of cyclodepsipeptides with membranes and of their complexation with alkali metal ions. , 1967, Biochemical and biophysical research communications.

[12]  A. Karlin.  Permeability and internal concentration of ions during depolarization of the electroplax. , 1967, Proceedings of the National Academy of Sciences of the United States of America.

[13]  J. H. Johnson,et al.  Antibiotic-mediated transport of alkali ions across lipid barriers. , 1967, Proceedings of the National Academy of Sciences of the United States of America.

[14]  A. W. Bernheimer.  Cytolytic toxins of bacterial origin. The nature and properties of cytolytic proteins are discussed with emphasis on staphylococcal alpha-toxin. , 1968, Science.

[15]  E. Schoffeniels,et al.  An isolated single electroplax preparation. I. New data on the effect of acetylcholine and related compounds. , 1957, Biochimica et biophysica acta.

[16]  T. L. Hill.  Electric fields and the cooperativity of biological membranes. , 1967, Proceedings of the National Academy of Sciences of the United States of America.