Age-related changes of the dental pulp complex and their relationship to systemic aging.

The dental pulp and its associated structures, the dentin and the cementum, are discussed. Because many of the age-related pulpal changes have components considered in several of the current theories of aging, these theories are briefly reviewed. Part 2 describes the age-related changes of the dental pulp, the dentin, and the cementum (the dental pulp complex). An attempt is made to differentiate inherent aging changes from physiologic defensive changes and pathologic irritant-induced changes. Part 3 describes the relationship of age-induced changes in the dental pulp complex to components of the current aging theories together with a unified concept of the dental pulp complex aging. Part 4 considers whether dental pulp complex aging can be used as a biomarker for generalized aging. Whether age-related changes of the dental pulp complex can be altered by interventions is discussed.

[1]  G. Bang,et al.  Determination of age in humans from root dentin transparency. , 1970, Acta odontologica Scandinavica.

[2]  F. Sayegh,et al.  Calcification in the dental pulp. , 1968, Oral surgery, oral medicine, and oral pathology.

[3]  Ronald W. Hart,et al.  Effect of chronic caloric restriction on physiological variables related to energy metabolism in the male Fischer 344 rat , 1989, Mechanisms of Ageing and Development.

[4]  B. Levy,et al.  Cemental Annulation as an Age Criterion in Forensic Dentistry , 1982, Journal of dental research.

[5]  W. Ketterl.  Age-induced changes in the teeth and their attachment apparatus. , 1983, International dental journal.

[6]  D R Morse,et al.  Oral digestion of a complex-carbohydrate cereal: effects of stress and relaxation on physiological and salivary measures. , 1989, The American journal of clinical nutrition.

[7]  M. Altini.  Age determination from the teeth - a review. , 1983, The Journal of the Dental Association of South Africa = Die Tydskrif van die Tandheelkundige Vereniging van Suid-Afrika.

[8]  R. Hopp,et al.  [Age determination by teeth]. , 1980, Deutsche zahnarztliche Zeitschrift.

[9]  S. Benet.  How to live to be 100: The life-style of the people of the Caucasus , 1976 .

[10]  M. Dard,et al.  A transmission electron microscope study of fibroblast changes in human deciduous tooth pulp. , 1989, Archives of oral biology.

[11]  S. Bernick,et al.  Effect of aging on the human pulp. , 1975, Journal of endodontics.

[12]  A. Miles.  Dentition in the Estimation of Age , 1963 .

[13]  S. Seltzer.  Endodontology; biologic considerations in endodontic procedures , 1971 .

[14]  B. Orban.  Oral histology and embryology , 1957 .

[15]  Morse DonaldR..  Stress and Bruxism: A Critical Review and Report of Cases , 1982 .

[16]  M. Weinreb,et al.  The effect of aging on tooth morphology: a study on impacted teeth. , 1986, Oral surgery, oral medicine, and oral pathology.

[17]  R. Sognnaes,et al.  Sclerotic Age Changes in Root Dentin of Human Teeth as Observed by Optical, Electron, and X-Ray Microscopy , 1960, Journal of dental research.

[18]  P. Carrigan,et al.  A scanning electron microscopic evaluation of human dentinal tubules according to age and location. , 1984, Journal of endodontics.

[19]  C. C. Johnson.  Transparent dentine in age estimation. , 1968, Oral surgery, oral medicine, and oral pathology.

[20]  M. Kneale,et al.  The dentine-predentine interface in human teeth. A scanning electron microscope study , 1979, British Dental Journal.

[21]  J. P. Bentley,et al.  Age-related changes in reducible crosslinks of human dental pulp collagen. , 1983, Archives of oral biology.

[22]  D R Morse,et al.  A unified theory of aging. , 1990, International journal of psychosomatics : official publication of the International Psychosomatics Institute.

[23]  R. Feigal,et al.  Effects of endodontic materials on cell viability across standard pore size filters. , 1985, Journal of endodontics.

[24]  J L Bada,et al.  Aspartic acid racemization in tooth enamel from living humans. , 1975, Proceedings of the National Academy of Sciences of the United States of America.

[25]  S. Will.  Tested accuracy of a decedent's age by teeth. , 1985, Journal.

[26]  S. Seltzer,et al.  Classification of pulpal pathosis. , 1972, Oral surgery, oral medicine, and oral pathology.

[27]  Sognnaes Rf.  Forensic stomatology (second of three parts). , 1977, The New England journal of medicine.

[28]  G. Gustafson,et al.  Age Determinations on Teeth , 1950 .

[29]  D. Morse.  Clinical endodontology : a comprehensive guide to diagnosis, treatment, and prevention , 1974 .

[30]  W. G. Shafer,et al.  Textbook of Oral Pathology , 1974 .

[31]  R. Kronfeld,et al.  Kronfeld's Histopathology of the teeth and their surrounding structures , 1933 .

[32]  H. Grahnén,et al.  Fluoride and dental age. , 1975, Acta odontologica Scandinavica.

[33]  S. Malhotra.  Dietary factors in a study of cancer colon from Cancer Registry, with special reference to the role of saliva, milk and fermented milk products and vegetable fibre. , 1977, Medical hypotheses.

[34]  S. Seltzer,et al.  The dental pulp: Biologic considerations in dental procedures , 1965 .

[35]  H. Zander,et al.  Continuous Cementum Apposition , 1958, Journal of dental research.