Branched chain amino acid metabolism profiles in progressive human nonalcoholic fatty liver disease

[1]  Yukihiro Shimizu,et al.  Branched-chain amino acids in liver diseases. , 2013, World journal of gastroenterology.

[2]  Mark Sanders,et al.  Expedient data mining for nontargeted high-resolution LC-MS profiles of biological samples. , 2013, Bioanalysis.

[3]  D. Fotiadis,et al.  The small SLC43 family: facilitator system l amino acid transporters and the orphan EEG1. , 2013, Molecular aspects of medicine.

[4]  C. Hoppel,et al.  Leucine and Protein Metabolism in Obese Zucker Rats , 2013, PloS one.

[5]  Z. Lu,et al.  Altered UDP-Glucuronosyltransferase and Sulfotransferase Expression and Function during Progressive Stages of Human Nonalcoholic Fatty Liver Disease , 2013, Drug Metabolism and Disposition.

[6]  F. Vaz,et al.  Acylcarnitines , 2012, Diabetes.

[7]  A. Hofman,et al.  Prevalence and risk factors of non-alcoholic fatty liver disease in the elderly: results from the Rotterdam study. , 2012, Journal of hepatology.

[8]  M. Palacín,et al.  T‐type amino acid transporter TAT1 (Slc16a10) is essential for extracellular aromatic amino acid homeostasis control , 2012, The Journal of physiology.

[9]  T. Kawaguchi,et al.  Effect of branched-chain amino acid-enriched nutritional supplementation on interferon therapy in Japanese patients with chronic hepatitis C virus infection: a retrospective study , 2012, Virology Journal.

[10]  T. Fujiwara,et al.  Branched-chain amino acid-enriched nutrients improve nutritional and metabolic abnormalities in the early post-transplant period after living donor liver transplantation , 2012, Journal of hepato-biliary-pancreatic sciences.

[11]  A. Tee,et al.  Leucine and mTORC1: a complex relationship. , 2012, American journal of physiology. Endocrinology and metabolism.

[12]  C. Newgard.  Interplay between lipids and branched-chain amino acids in development of insulin resistance. , 2012, Cell metabolism.

[13]  Asami Hagiwara,et al.  Branched‐chain amino acids prevent insulin‐induced hepatic tumor cell proliferation by inducing apoptosis through mTORC1 and mTORC2‐dependent mechanisms , 2012, Journal of cellular physiology.

[14]  I. Dagher,et al.  Housekeeping gene variability in the liver of alcoholic patients. , 2012, Alcoholism, clinical and experimental research.

[15]  早石 宗右.  Oral branched-chain amino acid granules reduce the incidence of hepatocellular carcinoma and improve event-free survival in patients with liver cirrhosis , 2012 .

[16]  Y. Hiasa,et al.  Long-term branched-chain amino acid supplementation improves glucose tolerance in patients with nonalcoholic steatohepatitis-related cirrhosis. , 2012, Internal medicine.

[17]  J. Calviño,et al.  Insulin resistance and the metabolism of branched-chain amino acids in humans , 2011, Amino Acids.

[18]  G. Scheffer,et al.  Variations in ATP-Binding Cassette Transporter Regulation during the Progression of Human Nonalcoholic Fatty Liver Disease , 2011, Drug Metabolism and Disposition.

[19]  S. Adams.  Emerging perspectives on essential amino acid metabolism in obesity and the insulin-resistant state. , 2011, Advances in nutrition.

[20]  A. McCullough.  Epidemiology of the metabolic syndrome in the USA , 2011, Journal of digestive diseases.

[21]  D. Billheimer,et al.  Analysis of Global and Absorption, Distribution, Metabolism, and Elimination Gene Expression in the Progressive Stages of Human Nonalcoholic Fatty Liver Disease , 2011, Drug Metabolism and Disposition.

[22]  Vincent Wai-Sun Wong,et al.  Prevalence of non-alcoholic fatty liver disease and advanced fibrosis in Hong Kong Chinese: a population study using proton-magnetic resonance spectroscopy and transient elastography , 2011, Gut.

[23]  N. Cherrington,et al.  Drug metabolism alterations in nonalcoholic fatty liver disease , 2011, Drug metabolism reviews.

[24]  M. Milburn,et al.  Plasma metabolomic profile in nonalcoholic fatty liver disease. , 2011, Metabolism: clinical and experimental.

[25]  P. Desmond,et al.  Expression of common housekeeping genes is affected by disease in human hepatitis C virus‐infected liver , 2011, Liver international : official journal of the International Association for the Study of the Liver.

[26]  吉田 龍一.  Branched-chain amino acid-enriched nutrients improve nutritional and metabolic abnormalities in the early post-transplant period after living donor liver transplantation , 2011 .

[27]  G. Bedogni,et al.  Epidemiology of Non-Alcoholic Fatty Liver Disease , 2010, Digestive Diseases.

[28]  S. Klein,et al.  Obesity and nonalcoholic fatty liver disease: Biochemical, metabolic, and clinical implications , 2010, Hepatology.

[29]  J. Ranger-Moore,et al.  Hepatic Cytochrome P450 Enzyme Alterations in Humans with Progressive Stages of Nonalcoholic Fatty Liver Disease The online version of this article (available at http://dmd.aspetjournals.org) contains supplemental material. , 2009, Drug Metabolism and Disposition.

[30]  Svati H Shah,et al.  A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. , 2009, Cell metabolism.

[31]  K. Cusi,et al.  New diagnostic and treatment approaches in non-alcoholic fatty liver disease (NAFLD) , 2009, Annals of medicine.

[32]  J. Schwimmer,et al.  Hepatic, Cardiovascular, and Endocrine Outcomes of the Histological Subphenotypes of Nonalcoholic Fatty Liver Disease , 2008, Seminars in liver disease.

[33]  D. Greco,et al.  Gene expression in human NAFLD. , 2008, American journal of physiology. Gastrointestinal and liver physiology.

[34]  Pengxiang She,et al.  Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism. , 2007, American journal of physiology. Endocrinology and metabolism.

[35]  F. Bessho,et al.  Protein characterization of NA+-independent system L amino acid transporter 3 in mice: a potential role in supply of branched-chain amino acids under nutrient starvation. , 2007, The American journal of pathology.

[36]  A. McCullough.  Pathophysiology of nonalcoholic steatohepatitis. , 2006, Journal of clinical gastroenterology.

[37]  E. Bonora,et al.  Metabolic syndrome and cardiovascular disease , 2007, Annals of clinical biochemistry.

[38]  M. Hediger,et al.  Characterization of a branched-chain amino-acid transporter SBAT1 (SLC6A15) that is expressed in human brain. , 2005, Biochemical and biophysical research communications.

[39]  O. Cummings,et al.  Design and validation of a histological scoring system for nonalcoholic fatty liver disease , 2005, Hepatology.

[40]  P Christoffersen,et al.  Long term prognosis of fatty liver: risk of chronic liver disease and death , 2004, Gut.

[41]  M. Willingham,et al.  Branched-chain amino acid catabolism: unique segregation of pathway enzymes in organ systems and peripheral nerves. , 2004, American journal of physiology. Endocrinology and metabolism.

[42]  C. Day.  Pathogenesis of steatohepatitis. , 2002, Best practice & research. Clinical gastroenterology.

[43]  G. Marchesini,et al.  Nonalcoholic fatty liver disease: a feature of the metabolic syndrome. , 2001, Diabetes.

[44]  R. Harris,et al.  A molecular model of human branched-chain amino acid metabolism. , 1998, The American journal of clinical nutrition.

[45]  C. Day,et al.  Steatohepatitis: a tale of two "hits"? , 1998, Gastroenterology.