Autoinhibition as a transcriptional regulatory mechanism.

[1]  Y. Kanno,et al.  Intrinsic Transcriptional Activation-Inhibition Domains of the Polyomavirus Enhancer Binding Protein 2/Core Binding Factor α Subunit Revealed in the Presence of the β Subunit , 1998, Molecular and Cellular Biology.

[2]  Jeffrey A. Lefstin,et al.  Allosteric effects of DNA on transcriptional regulators , 1998, Nature.

[3]  B. Graves,et al.  Inner Workings of a Transcription Factor Partnership , 1998, Science.

[4]  Cynthia Wolberger,et al.  The Structure of GABPα/β: An ETS Domain- Ankyrin Repeat Heterodimer Bound to DNA , 1998 .

[5]  D. Lane,et al.  The N terminus of the murine p53 tumour suppressor is an independent regulatory domain affecting activation and thermostability. , 1998, Journal of molecular biology.

[6]  A. Leutz,et al.  B-Myb, a repressed trans-activating protein , 1997, Journal of Molecular Medicine.

[7]  Wei Gu,et al.  Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain , 1997, Cell.

[8]  A. Sharrocks,et al.  Molecular characterization of the B‐box protein–protein interaction motif of the ETS‐domain transcription factor Elk‐1 , 1997, The EMBO journal.

[9]  R. Morimoto,et al.  Repression of the heat shock factor 1 transcriptional activation domain is modulated by constitutive phosphorylation , 1997, Molecular and cellular biology.

[10]  N. Hernandez,et al.  Role for the Amino-Terminal Region of Human TBP in U6 snRNA Transcription , 1997, Science.

[11]  M. Gillespie,et al.  DNA binding by the ETS domain , 1996, Nature.

[12]  A. Brass,et al.  Pip, a lymphoid-restricted IRF, contains a regulatory domain that is important for autoinhibition and ternary complex formation with the Ets factor PU.1. , 1996, Genes & development.

[13]  R. Mann,et al.  A structural model for a homeotic protein-extradenticle-DNA complex accounts for the choice of HOX protein in the heterodimer. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[14]  B. Graves,et al.  Characterization of the cooperative function of inhibitory sequences in Ets-1 , 1996, Molecular and cellular biology.

[15]  R. Krumlauf,et al.  An extradenticle‐induced conformational change in a HOX protein overcomes an inhibitory function of the conserved hexapeptide motif. , 1996, The EMBO journal.

[16]  C. Prives,et al.  p53: puzzle and paradigm. , 1996, Genes & development.

[17]  R. Kodandapani,et al.  A new pattern for helix–turn–helix recognition revealed by the PU.l ETS–domain–DNA complex , 1996, Nature.

[18]  A. Nairn,et al.  Structural Basis for the Autoinhibition of Calcium/Calmodulin-Dependent Protein Kinase I , 1996, Cell.

[19]  P. Defossez,et al.  Two functionally distinct domains responsible for transactivation by the Ets family member ERM. , 1996, Oncogene.

[20]  X. Y. Li,et al.  Intramolecular inhibition of activating transcription factor-2 function by its DNA-binding domain. , 1996, Genes & development.

[21]  L. McIntosh,et al.  Solution structure of the ETS domain from murine Ets‐1: a winged helix‐turn‐helix DNA binding motif. , 1996, The EMBO journal.

[22]  F. Alt,et al.  Increased T-cell apoptosis and terminal B-cell differentiation induced by inactivation of the Ets-1 proto-oncogene , 1995, Nature.

[23]  N. Muthusamy,et al.  Defective activation and survival of T cells lacking the Ets-1 transcription factor , 1995, Nature.

[24]  R Grosschedl,et al.  Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions. , 1995, Genes & development.

[25]  R. Meadows,et al.  Solution structure of the ets domain of Fli-1 when bound to DNA , 1994, Nature Structural Biology.

[26]  Jeffrey A. Lefstin,et al.  Influence of a steroid receptor DNA-binding domain on transcriptional regulatory functions. , 1994, Genes & development.

[27]  L. McIntosh,et al.  Secondary structure of the ETS domain places murine Ets-1 in the superfamily of winged helix-turn-helix DNA-binding proteins. , 1994, Biochemistry.

[28]  B. Graves,et al.  Identification of ETS domain proteins in murine T lymphocytes that interact with the Moloney murine leukemia virus enhancer , 1994, Molecular and cellular biology.

[29]  B. Wasylyk,et al.  Net, a new ets transcription factor that is activated by Ras. , 1994, Genes & development.

[30]  B. Kemp,et al.  Insights into autoregulation from the crystal structure of twitchin kinase , 1994, Nature.

[31]  J. Erickson,et al.  Real‐time DNA binding measurements of the ETSl recombinant oncoproteins reveal significant kinetic differences between the p42 and p51 isoforms , 1994, Protein science : a publication of the Protein Society.

[32]  C. Gross,et al.  Amino-terminal amino acids modulate sigma-factor DNA-binding activity. , 1993, Genes & development.

[33]  R. Brennan The winged-helix DNA-binding motif: Another helix-turn-helix takeoff , 1993, Cell.

[34]  M. Schmidt,et al.  Effect of the non-conserved N-terminus on the DNA binding activity of the yeast TATA binding protein. , 1993, Nucleic acids research.

[35]  D. Lane,et al.  Regulation of the specific DNA binding function of p53 , 1992, Cell.

[36]  R. Grosschedl,et al.  An inhibitory carboxyl-terminal domain in Ets-1 and Ets-2 mediates differential binding of ETS family factors to promoter sequences of the mb-1 gene. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[37]  D. Baltimore,et al.  The NF‐kappa B p50 precursor, p105, contains an internal I kappa B‐like inhibitor that preferentially inhibits p50. , 1992, The EMBO journal.

[38]  R. Treisman,et al.  Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element , 1992, Cell.

[39]  T. Graf,et al.  DNA binding by c‐Ets‐1, but not v‐Ets, is repressed by an intramolecular mechanism. , 1992, The EMBO journal.

[40]  R. Fisher,et al.  High-affinity DNA-protein interactions of the cellular ETS1 protein: the determination of the ETS binding motif. , 1991, Oncogene.

[41]  M. Cleary Oncogenic conversion of transcription factors by chromosomal translocations , 1991, Cell.

[42]  R. Pearson,et al.  Intrasteric regulation of protein kinases and phosphatases. , 1991, Biochimica et biophysica acta.

[43]  M. Klemsz,et al.  The ETS-domain: a new DNA-binding motif that recognizes a purine-rich core DNA sequence. , 1990, Genes & development.

[44]  B. Graves,et al.  Specificity within the ets family of transcription factors. , 1998, Advances in cancer research.

[45]  S. Burley DNA-binding motifs from eukaryotic transcription factors , 1994 .