论文信息 - A Case of Malignant Transformation in a Congenital Cystic Adenomatoid Malformation

A Case of Malignant Transformation in a Congenital Cystic Adenomatoid Malformation

Congenital cystic adenomatoid malformation (CCAM) of the lung is a rare condition with the potential for malignant transformation. Several cases that presented with malignant changes have been reported worldwide. However, no report about a malignant transformation case in a CCAM in Korea has been published. We report the first patient who had a malignant change in a CCAM. A 32-year-old female underwent a bilobectomy for a cystic lung lesion that was a type 1 CCAM associated with malignant transformation. A biopsy specimen from the resected cystic lesion showed foci of adenocarcinoma. (Korean J Med 2014; 86:500-504)

[1] A. Niven,et al. Congenital Pulmonary Airway Malformation: A Case Report and Review of the Literature , 2012, Respiratory Care.

[2] B. Shehata,et al. Mucinous adenocarcinoma of the lung in association with congenital pulmonary airway malformation. , 2010, Journal of pediatric surgery.

[3] A. Nicholson,et al. Bronchioloalveolar carcinoma in congenital cystic adenomatoid malformation of lung. , 2007, The Annals of thoracic surgery.

[4] C. Lim,et al. Congenital cystic adenomatoid malformation of the lung in adults: Clinical and CT evaluation of seven patients , 2006, Respirology.

[5] A. Nicholson,et al. Metastases from bronchioloalveolar carcinomas associated with long‐standing type 1 congenital cystic adenomatoid malformations. A report of two cases , 2006, Histopathology.

[6] P. Russo,et al. Outcome of the Prenatally Diagnosed Congenital Cystic Adenomatoid Lung Malformation: A Canadian Experience , 2001, Fetal Diagnosis and Therapy.

[7] C. Gambini,et al. Bronchioloalveolar carcinoma arising in congenital cystic adenomatoid malformation in a child: A case report and review on malignancies originating in congenital cystic adenomatoid malformation , 1998, Pediatric pulmonology.

[8] R. Drake,et al. Congenital cystic adenomatoid malformation of the lung. Classification and morphologic spectrum. , 1977, Human pathology.

[9] C. Ky,et al. Congenital adenomatoid malformation of one lobe of a lung with general anasarca. , 1949 .