The effect of passive immunization with hetero and isoimmune anti-ovary antiserum on the feritlization of mouse, rat and hamster eggs.

The effect of passive immunization with hetero and isoimmune antiovary antiserum on the fertilization of mouse, rat, and hamster eggs was determined. Fertilization of the eggs could be inhibited by a single ip injection of respective antiovary antiserum obtained from rabbits. The antiovary antisera absorbed with the ovary did not prevent fertilization but antisera absorbed with the liver and kidney inhibited fertilization was not inhibited by a single ip injection of antiovary antiserum obtained from rats and mice, respectively. Fertilization in vitro of mouse eggs was low in the presence of control serum but was significantly reduced in the presence of antiserum (p less than .001).

[1]  Y. Tsunoda,et al.  Effect of anti-rat ovary antiserum on the fertilization of rat, mouse and hamster eggs in vivo and in vitro. , 1976, Biology of reproduction.

[2]  Y. Tsunoda,et al.  In vivo and in vitro fertilization of hamster, rat and mouse eggs after treatment with anti-hamster ovary antiserum. , 1976, The Journal of experimental zoology.

[3]  Y. Tsunoda,et al.  Fertilizing ability in vivo and in vitro of spermatozoa of rats and mice treated with alpha-chlorohydrin. , 1976, Journal of reproduction and fertility.

[4]  R. Yanagimachi,et al.  Block of hamster fertilization by anti-ovary antibody. , 1975, Journal of reproduction and fertility.

[5]  A. Pavlok,et al.  Antibodies against mouse ovaries and their effect on fertilization in vitro and in vivo in the mouse. , 1975, Journal of reproduction and fertility.

[6]  J. Hanson,et al.  An immunologic approach to contraception: localization of antiembryo and antizona pellucida serum during mouse preimplantation development. , 1974, Fertility and Sterility.

[7]  L. E. Franklin,et al.  Inhibition of Sperm-Egg Interaction by Specific Antibody , 1972, Science.

[8]  S. Shahani,et al.  Immunobiological studies with the reproductive organs, adrenals and spleen of the female mouse. , 1972, International journal of fertility.

[9]  Porter Cw.  Ovarian antibodies in female guinea pigs. , 1965 .

[10]  C. Porter.  Ovarian antibodies in female guinea pigs. , 1965, International journal of fertility.

[11]  S. Isojima,et al.  Antigenicity of guinea pig testis and ovary. , 1959, International archives of allergy and applied immunology.