论文信息 - A brain signature for acute pain

A brain signature for acute pain

Wager and colleagues developed a functional MRI-based spatial and magnitude pattern for perception of acute pain, which seems to generalize across many task conditions and subjects. This is a strong demonstration of the existence of a pain signature and raises important questions regarding what pain and perception are.

A. Vania Apkarian | A. Apkarian

[1] R. Treede,et al. Human brain mechanisms of pain perception and regulation in health and disease , 2005, European journal of pain.

[2] G. Holmes,et al. Sensory disturbances from cerebral lesions , 1911 .

[3] M. Baliki,et al. A dynamic network perspective of chronic pain , 2012, Neuroscience Letters.

[4] Gian Domenico Iannetti,et al. A multisensory investigation of the functional significance of the “pain matrix” , 2011, NeuroImage.

[5] Mark Tommerdahl,et al. Role of primary somatosensory cortex in the coding of pain , 2013, PAIN®.

[6] Li Min Chen,et al. Differential fMRI activation to noxious heat and tactile stimuli in parasylvian areas of new world monkeys , 2012, PAIN.

[7] Russell A. Poldrack,et al. Large-scale automated synthesis of human functional neuroimaging data , 2011, Nature Methods.

[8] W. Penfield,et al. SOMATIC MOTOR AND SENSORY REPRESENTATION IN THE CEREBRAL CORTEX OF MAN AS STUDIED BY ELECTRICAL STIMULATION , 1937 .

[9] L. Garcia-Larrea. Insights gained into pain processing from patients with focal brain lesions , 2012, Neuroscience Letters.