Recording of Bone Marrow Activity in Liver-Spleen (RES) Scintigraphy

The bone marrow activity in the liver-spleen (RES) scintigraphy has been diffucult to estimate correctly. If the activity of the bone marrow is to be decided as counts/time unit it is of importance that structures with a high activity as the liver and spleen are excluded from the registration. A dorsal registration of the pelvis during 180 s will give a rather correct information of bone marrow activity and besides an image of the pelvic bone marrow is obtained. Using 270 to 280 MBq 99Tcm-Albures all 45 normal cases had values below 150 KCNT (1 KCNT = 1000 counts). All cases with cirrhosis (n=15) or metastases in the liver (n=14) had values over 150 KCNT. Values over 150 KCNT were also found in 29 of 34 patients with an increase in ASAT and ALAT (GOT, GPT) as the only pathologic finding and in 12 of 21 patients with a carcinoma but without metastases in the liver.

[1]  Y. Inoue,et al.  Abnormally high diffuse activity on bone scintigram the importance of exposure time for its recognition , 1982, European Journal of Nuclear Medicine.

[2]  T. Lahtinen,et al.  Increased bone marrow blood flow in polycythemia vera , 2004, European Journal of Nuclear Medicine.

[3]  J. Witte,et al.  Effects of physical stress and pharmacologically induced coronary dilation on myocardial and non-myocardial 201Thallium-uptake , 2004, European Journal of Nuclear Medicine.

[4]  L. Friman.  Distribution of the Extrahepatic Uptake in Liver Diseases as Recorded by Scintigraphy , 1981, Acta radiologica: diagnosis.

[5]  L. Friman.  Splenomegaly, Hyperkinetic Splenic Flow and Portal Hypertension in Colitis , 1980, Acta radiologica: diagnosis.

[6]  W. Kaplan,et al.  The effect of cancer chemotherapeutic agents on the liver-spleen scan. , 1980, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[7]  G. Glober,et al.  Simple computer quantitation of spleen-to-liver ratios in the diagnosis of hepatocellular disease. , 1979, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[8]  D. Drum,et al.  Liver scintigraphic features associated with alcoholism. , 1978, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[9]  G. E. Geslien,et al.  The sensitivity and specificity of 99mTc-sulfur colloid liver imaging in diffuse hepatocellular disease. , 1976, Radiology.

[10]  J. Keyes,et al.  The significance of the liver-spleen uptake ration in liver scannning. , 1974, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[11]  E. Wheelock,et al.  The role of macrophages in defense against neoplastic disease. , 1974, Advances in cancer research.