Actin-dependent tumour cell adhesion after short-term exposure to the antimetastasis ruthenium complex NAMI-A.

[1]  G. Nicolson,et al.  Role of the cytoskeleton in adhesion stabilization of human colorectal carcinoma cells to extracellular matrix components under dynamic conditions of laminar flow , 2004, Clinical & Experimental Metastasis.

[2]  T. Irimura,et al.  Regulation of melanoma cell migration and invasion by laminin-5 and α3β1 integrin (VLA-3) , 2004, Clinical & Experimental Metastasis.

[3]  G. Pezzoni,et al.  Dual Action of NAMI-A in inhibition of solid tumor metastasis: selective targeting of metastatic cells and binding to collagen. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

[4]  G. Sava,et al.  Inhibition of the MEK/ERK signaling pathway by the novel antimetastatic agent NAMI-A down regulates c-myc gene expression and endothelial cell proliferation. , 2002, European journal of biochemistry.

[5]  A. Bergamo,et al.  Tumour cell uptake of the metastasis inhibitor ruthenium complex NAMI-A and its in vitro effects on KB cells , 2002, Cancer Chemotherapy and Pharmacology.

[6]  G. Sava,et al.  The anti-metastatic agent imidazolium trans-imidazoledimethylsulfoxide-tetrachlororuthenate induces endothelial cell apoptosis by inhibiting the mitogen-activated protein kinase/extracellular signal-regulated kinase signaling pathway. , 2002, Archives of biochemistry and biophysics.

[7]  R. Fässler,et al.  Integrins in invasive growth. , 2002, The Journal of clinical investigation.

[8]  E. Thompson,et al.  Mechanisms of tumour invasion and metastasis: emerging targets for therapy , 2002, Expert opinion on therapeutic targets.

[9]  D. Ribatti,et al.  Inhibition of endothelial cell functions and of angiogenesis by the metastasis inhibitor NAMI-A , 2002, British Journal of Cancer.

[10]  M. Bashyam.  Understanding cancer metastasis , 2002, Cancer.

[11]  S. Grinstein,et al.  Phagocytosis and innate immunity. , 2002, Current opinion in immunology.

[12]  Katsuo Suzuki,et al.  Actin filament assembly and actin‐myosin contractility are necessary for anchorage‐ and EGF‐dependent activation of phospholipase Cγ , 2001, Journal of cellular physiology.

[13]  V. Ullrich,et al.  Inhibition of neutrophil spreading during adhesion to fibronectin reveals formation of long tubulovesicular cell extensions (cytonemes). , 2001, Experimental cell research.

[14]  A. Bergamo,et al.  Tumour cell uptake G2-M accumulation and cytotoxicity of NAMI-A on TS/A adenocarcinoma cells. , 2001, Anticancer research.

[15]  A. Bergamo,et al.  Lack of In vitro cytotoxicity, associated to increased G(2)-M cell fraction and inhibition of matrigel invasion, may predict In vivo-selective antimetastasis activity of ruthenium complexes. , 2000, The Journal of pharmacology and experimental therapeutics.

[16]  Garay Rp.  Cellular mechanisms of smooth muscle contraction , 2000 .

[17]  G. Sava,et al.  In vitro growth of TS/A adenocarcinoma and of the gene transfected TS/A-IL4 line on biological substrates. , 2000, Anticancer Research.

[18]  G. Nicolson,et al.  Different adhesion properties of highly and poorly metastatic HT-29 colon carcinoma cells with extracellular matrix components: role of integrin expression and cytoskeletal components , 1999, British Journal of Cancer.

[19]  A. Bergamo,et al.  In vitro cell cycle arrest, in vivo action on solid metastasizing tumors, and host toxicity of the antimetastatic drug NAMI-A and cisplatin. , 1999, The Journal of pharmacology and experimental therapeutics.

[20]  G. Sava,et al.  Reduction of lung metastasis by ImH[trans-RuCl4(DMSO)Im]: mechanism of the selective action investigated on mouse tumors. , 1999, Anti-cancer drugs.

[21]  T. Springer,et al.  Folding of the β-propeller domain of the integrin αL subunit is independent of the I domain and dependent on the β2 subunit , 1997 .

[22]  C. Marzano,et al.  DNA damage and cytotoxcity induced in mammalian cells by a tetramethylfuroquinolinone derivative , 1997, Environmental and molecular mutagenesis.

[23]  P. Dri,et al.  Chloride ion efflux regulates adherence, spreading, and respiratory burst of neutrophils stimulated by tumor necrosis factor-alpha (TNF) on biologic surfaces , 1996, The Journal of cell biology.

[24]  V. Vetvicka,et al.  Analysis of the sugar specificity and molecular location of the beta-glucan-binding lectin site of complement receptor type 3 (CD11b/CD18). , 1996, Journal of immunology.

[25]  P. Patriarca,et al.  A new, one‐step assay on whole cell suspensions for peroxidase secretion by human neutrophils and eosinophils , 1992, Journal of leukocyte biology.

[26]  P. Janmey,et al.  MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium–calmodulin , 1992, Nature.

[27]  M. Nagase,et al.  Determination of ruthenium in biological tissue by graphite furnace AAS after decomposition of the sample by tetramethylammonium hydroxide. , 1992 .

[28]  D. Scudiero,et al.  New colorimetric cytotoxicity assay for anticancer-drug screening. , 1990, Journal of the National Cancer Institute.

[29]  S. Zigmond,et al.  Polymorphonuclear leukocyte adherence induces actin polymerization by a transduction pathway which differs from that used by chemoattractants , 1989, The Journal of cell biology.

[30]  D. Craciunescu,et al.  Cytostatic and antitumour properties of a new series of Pt (II) complexes with cyclopentylamine. , 1987, In Vivo.

[31]  A. Benedetti,et al.  Calcium sequestration activity in rat liver microsomes. Evidence for a cooperation of calcium transport with glucose-6-phosphatase. , 1985, Biochimica et biophysica acta.

[32]  J. Strominger,et al.  Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[33]  H. Eagle,et al.  Amino acid metabolism in mammalian cell cultures. , 1959, Science.