40 – Nuclear Mechanisms of Glucocorticoid Action

[1]  C. Glass,et al.  Nuclear Receptor-Enhanced Transcription Requires Motor- and LSD1-Dependent Gene Networking in Interchromatin Granules , 2008, Cell.

[2]  C. Glass,et al.  RETRACTED: Nuclear Receptor-Enhanced Transcription Requires Motor- and LSD1-Dependent Gene Networking in Interchromatin Granules , 2008, Cell.

[3]  J. Stamatoyannopoulos,et al.  Interaction of the Glucocorticoid Receptor with the Chromatin Landscape , 2008, Molecular cell.

[4]  Rolf Ohlsson,et al.  High-resolution circular chromosome conformation capture assay , 2008, Nature Protocols.

[5]  B. Cairns,et al.  Chromatin remodeling: insights and intrigue from single-molecule studies , 2007, Nature Structural &Molecular Biology.

[6]  W. D. Laat,et al.  An evaluation of 3C-based methods to capture DNA interactions , 2007, Nature Methods.

[7]  J. Dekker,et al.  Chromosome Conformation Capture Carbon Copy Technology , 2007, Current protocols in molecular biology.

[8]  Alexia S. Miller,et al.  Effects of different osmolytes on the induced folding of the N-terminal activation domain (AF1) of the glucocorticoid receptor. , 2007, Archives of biochemistry and biophysics.

[9]  D. Picard,et al.  The glucocorticoid responses are shaped by molecular chaperones , 2007, Molecular and Cellular Endocrinology.

[10]  P. Piper,et al.  Expressed as the sole Hsp90 of yeast, the α and β isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90β generates sensitivity to the Hsp90 inhibitor radicicol , 2007 .

[11]  Hao Li,et al.  Determinants of Cell- and Gene-Specific Transcriptional Regulation by the Glucocorticoid Receptor , 2007, PLoS genetics.

[12]  B. O’Malley.  Coregulators: from whence came these "master genes". , 2007, Molecular endocrinology.

[13]  H. Kinyamu,et al.  Proteasome Activity Modulates Chromatin Modifications and RNA Polymerase II Phosphorylation To Enhance Glucocorticoid Receptor-Mediated Transcription , 2007, Molecular and Cellular Biology.

[14]  G. Hager,et al.  Ligand-Specific Dynamics of the Androgen Receptor at Its Response Element in Living Cells , 2007, Molecular and Cellular Biology.

[15]  J. Collins,et al.  Human Glucocorticoid Receptor β Binds RU-486 and Is TranscriptionallyActive , 2007, Molecular and Cellular Biology.

[16]  D. Picard,et al.  2-color photobleaching experiments reveal distinct intracellular dynamics of two components of the Hsp90 complex. , 2006, Experimental cell research.

[17]  Ming-Jing Hwang,et al.  Role of SUMO-interacting motif in Daxx SUMO modification, subnuclear localization, and repression of sumoylated transcription factors. , 2006, Molecular cell.

[18]  G. Hager,et al.  Single-cell analysis of glucocorticoid receptor action reveals that stochastic post-chromatin association mechanisms regulate ligand-specific transcription. , 2006, Molecular endocrinology.

[19]  T. Kodadek,et al.  Keeping Transcriptional Activators under Control , 2006, Cell.

[20]  J. Torchia,et al.  The Activity and Stability of the Transcriptional Coactivator p/CIP/SRC-3 Are Regulated by CARM1-Dependent Methylation , 2006, Molecular and Cellular Biology.

[21]  W. Wurst,et al.  The Hsp90 Cochaperone p23 Is Essential for Perinatal Survival , 2006, Molecular and Cellular Biology.

[22]  Julia Tischler,et al.  Negative and Positive Regulation of Gene Expression by Mouse Histone Deacetylase1 , 2006, Molecular and Cellular Biology.

[23]  Myles A Brown,et al.  Estrogen receptor target gene: an evolving concept. , 2006, Molecular endocrinology.

[24]  Yingming Zhao,et al.  HDAC1 acetylation is linked to progressive modulation of steroid receptor-induced gene transcription. , 2006, Molecular cell.

[25]  L. Pearl,et al.  Structure and mechanism of the Hsp90 molecular chaperone machinery. , 2006, Annual review of biochemistry.

[26]  J. Cidlowski,et al.  Glucocorticoid receptor isoforms generate transcription specificity. , 2006, Trends in cell biology.

[27]  I. Adcock,et al.  New insights into the molecular mechanisms of corticosteroids actions. , 2006, Current drug targets.

[28]  Jeong Hoon Kim,et al.  Downstream signaling mechanism of the C-terminal activation domain of transcriptional coactivator CoCoA , 2006, Nucleic acids research.

[29]  R. Flavell,et al.  Managing Associations Between Different Chromosomes , 2006, Science.

[30]  A. Miele,et al.  Mapping Chromatin Interactions by Chromosome Conformation Capture , 2006, Current protocols in molecular biology.

[31]  J. Northrop,et al.  Histone H3 Lysine 9 Methyltransferase G9a Is a Transcriptional Coactivator for Nuclear Receptors* , 2006, Journal of Biological Chemistry.

[32]  Cem Elbi,et al.  Chromatin dynamics and the evolution of alternate promoter states , 2006, Chromosome Research.

[33]  Gioacchino Natoli,et al.  A hyper‐dynamic equilibrium between promoter‐bound and nucleoplasmic dimers controls NF‐κB‐dependent gene activity , 2006, The EMBO journal.

[34]  J. Buchner,et al.  The phosphatase Ppt1 is a dedicated regulator of the molecular chaperone Hsp90 , 2006, The EMBO journal.

[35]  I. Adcock,et al.  Histone deacetylase 2–mediated deacetylation of the glucocorticoid receptor enables NF-κB suppression , 2006, The Journal of experimental medicine.

[36]  D. Picard.  Intracellular dynamics of the Hsp90 co-chaperone p23 is dictated by Hsp90. , 2006, Experimental cell research.

[37]  E. Seto,et al.  Acetylation and deacetylation of non-histone proteins. , 2005, Gene.

[38]  H. Shih,et al.  SUMO modification negatively modulates the transcriptional activity of CREB-binding protein via the recruitment of Daxx. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[39]  David Owerbach,et al.  A proline-90 residue unique to SUMO-4 prevents maturation and sumoylation. , 2005, Biochemical and biophysical research communications.

[40]  A. Griswold,et al.  Individual histone deacetylases in Drosophila modulate transcription of distinct genes. , 2005, Genomics.

[41]  Michael Sendtner,et al.  Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells , 2005, Nature Neuroscience.

[42]  Heike Brand,et al.  Multiple mechanisms induce transcriptional silencing of a subset of genes, including oestrogen receptor α, in response to deacetylase inhibition by valproic acid and trichostatin A , 2005, Oncogene.

[43]  Michael G. Rosenfeld,et al.  Controlling nuclear receptors: the circular logic of cofactor cycles , 2005, Nature Reviews Molecular Cell Biology.

[44]  Jeong Hoon Kim,et al.  GAC63, a GRIP1-Dependent Nuclear Receptor Coactivator , 2005, Molecular and Cellular Biology.

[45]  C. Geserick,et al.  The role of DNA response elements as allosteric modulators of steroid receptor function , 2005, Molecular and Cellular Endocrinology.

[46]  W. Obermann,et al.  Aha1 competes with Hop, p50 and p23 for binding to the molecular chaperone Hsp90 and contributes to kinase and hormone receptor activation. , 2005, The Biochemical journal.

[47]  John A Cidlowski,et al.  Translational regulatory mechanisms generate N-terminal glucocorticoid receptor isoforms with unique transcriptional target genes. , 2005, Molecular cell.

[48]  R. Hay,et al.  SUMO: a history of modification. , 2005, Molecular cell.

[49]  K. Shokat,et al.  The F Box Protein Dsg1/Mdm30 Is a Transcriptional Coactivator that Stimulates Gal4 Turnover and Cotranscriptional mRNA Processing , 2005, Cell.

[50]  R. Kingston,et al.  Swapping function of two chromatin remodeling complexes. , 2005, Molecular cell.

[51]  H. Shih,et al.  Daxx Mediates the Small Ubiquitin-like Modifier-dependent Transcriptional Repression of Smad4* , 2005, Journal of Biological Chemistry.

[52]  B. O’Malley,et al.  Inhibition of the 26S proteasome blocks progesterone receptor-dependent transcription through failed recruitment of RNA polymerase II , 2005, The Journal of Steroid Biochemistry and Molecular Biology.

[53]  A. Sandelin,et al.  Prediction of nuclear hormone receptor response elements. , 2005, Molecular endocrinology.

[54]  Cem Elbi,et al.  Ligand-Specific Dynamics of the Progesterone Receptor in Living Cells and during Chromatin Remodeling In Vitro , 2005, Molecular and Cellular Biology.

[55]  M. Mayer,et al.  Hsp70 chaperones: Cellular functions and molecular mechanism , 2005, Cellular and Molecular Life Sciences.

[56]  F. Holsboer,et al.  FK506-binding Proteins 51 and 52 Differentially Regulate Dynein Interaction and Nuclear Translocation of the Glucocorticoid Receptor in Mammalian Cells* , 2005, Journal of Biological Chemistry.

[57]  C. Verrijzer,et al.  Composition and functional specificity of SWI2/SNF2 class chromatin remodeling complexes. , 2005, Biochimica et biophysica acta.

[58]  T. Yao,et al.  Chaperoning steroid hormone signaling via reversible acetylation , 2005, Nuclear receptor signaling.

[59]  Jennifer M Harrell,et al.  Evidence for Glucocorticoid Receptor Transport on Microtubules by Dynein* , 2004, Journal of Biological Chemistry.

[60]  G. Jenster,et al.  Negative Modulation of Androgen Receptor Transcriptional Activity by Daxx , 2004, Molecular and Cellular Biology.

[61]  D. Volk,et al.  TATA box binding protein induces structure in the recombinant glucocorticoid receptor AF1 domain. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[62]  G. Hager,et al.  UV Laser Cross-linking: A Real-Time Assay to Study Dynamic Protein/DNA Interactions During Chromatin Remodeling , 2004, Science's STKE.

[63]  G. Blatch,et al.  Hop: more than an Hsp70/Hsp90 adaptor protein , 2004, BioEssays : news and reviews in molecular, cellular and developmental biology.

[64]  T. Heinzel,et al.  Negative glucocorticoid receptor response elements and their role in glucocorticoid action. , 2004, Current pharmaceutical design.

[65]  E. Young,et al.  Cortisol pulsatility and its role in stress regulation and health , 2004, Frontiers in Neuroendocrinology.

[66]  B. Peterlin,et al.  VP16 and Ubiquitin Binding of P-TEFb via Its Activation Domain and Ubiquitin Facilitates Elongation of Transcription of Target Genes , 2004, Current Biology.

[67]  G. Hager,et al.  A Novel In Situ Assay for the Identification and Characterization of Soluble Nuclear Mobility Factors , 2004, Science's STKE.

[68]  Erica S. Johnson,et al.  Protein modification by SUMO. , 2004, Annual review of biochemistry.

[69]  G. Hager,et al.  Subnuclear Trafficking and Gene Targeting by Steroid Receptors , 2004, Annals of the New York Academy of Sciences.

[70]  M. Galigniana,et al.  Role of molecular chaperones in steroid receptor action. , 2004, Essays in biochemistry.

[71]  Ying Huang,et al.  Equilibrium interactions of corepressors and coactivators with agonist and antagonist complexes of glucocorticoid receptors. , 2004, Molecular endocrinology.

[72]  M. Garabedian,et al.  Modulation of Glucocorticoid Receptor Function via Phosphorylation , 2004, Annals of the New York Academy of Sciences.

[73]  J. Cidlowski,et al.  The Origin and Functions of Multiple Human Glucocorticoid Receptor Isoforms , 2004, Annals of the New York Academy of Sciences.

[74]  K. Yamamoto,et al.  Importin 7 and Importin / Importin Are Nuclear Import Receptors for the Glucocorticoid Receptor , 2003 .

[75]  G. Hager,et al.  Rapid periodic binding and displacement of the glucocorticoid receptor during chromatin remodeling. , 2004, Molecular cell.

[76]  T. Archer,et al.  Reconstitution of Glucocorticoid Receptor-Dependent Transcription In Vivo , 2004, Molecular and Cellular Biology.

[77]  James G. McNally,et al.  Rapid Glucocorticoid Receptor Exchange at a Promoter Is Coupled to Transcription and Regulated by Chaperones and Proteasomes , 2004, Molecular and Cellular Biology.

[78]  P. Csermely,et al.  Hsp90 isoforms: functions, expression and clinical importance , 2004, FEBS letters.

[79]  G. Hager,et al.  Dynamics of nuclear receptor movement and transcription. , 2004, Biochimica et biophysica acta.

[80]  H. Kinyamu,et al.  Modifying chromatin to permit steroid hormone receptor-dependent transcription. , 2004, Biochimica et biophysica acta.

[81]  Cem Elbi,et al.  Molecular chaperones function as steroid receptor nuclear mobility factors. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[82]  M. Stallcup,et al.  Developmentally Essential Protein Flightless I Is a Nuclear Receptor Coactivator with Actin Binding Activity , 2004, Molecular and Cellular Biology.

[83]  A. Sharrocks,et al.  SUMO promotes HDAC-mediated transcriptional repression. , 2004, Molecular cell.

[84]  C. Pickart.  Back to the Future with Ubiquitin , 2004, Cell.

[85]  K. Takano,et al.  Regulation of nuclear retention of glucocorticoid receptor by nuclear Hsp90 , 2004, Molecular and Cellular Endocrinology.

[86]  Heike Brand,et al.  Estrogen Receptor-α Directs Ordered, Cyclical, and Combinatorial Recruitment of Cofactors on a Natural Target Promoter , 2003, Cell.

[87]  J. Iñiguez-Lluhí,et al.  Direct and distinguishable inhibitory roles for SUMO isoforms in the control of transcriptional synergy , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[88]  R. Sunahara,et al.  The Hsp90 Cochaperone p23 Is the Limiting Component of the Multiprotein Hsp90/Hsp70-based Chaperone System in Vivo Where It Acts to Stabilize the Client Protein·Hsp90 Complex* , 2003, Journal of Biological Chemistry.

[89]  Jeong Hoon Kim,et al.  CoCoA, a nuclear receptor coactivator which acts through an N-terminal activation domain of p160 coactivators. , 2003, Molecular cell.

[90]  K. Yamamoto,et al.  Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[91]  H. Kawai,et al.  Overexpression of histone deacetylase HDAC1 modulates breast cancer progression by negative regulation of estrogen receptor α , 2003, International journal of cancer.

[92]  F. Melchior,et al.  SUMO: ligases, isopeptidases and nuclear pores. , 2003, Trends in biochemical sciences.

[93]  K. Yamamoto,et al.  Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA , 2003, Nature.

[94]  K. Glaser,et al.  Role of class I and class II histone deacetylases in carcinoma cells using siRNA. , 2003, Biochemical and biophysical research communications.

[95]  M. Morimoto,et al.  Yellow fluorescent protein-tagged and cyan fluorescent protein-tagged imaging analysis of glucocorticoid receptor and importins in single living cells. , 2003, Endocrinology.

[96]  Weidong Wang,et al.  BAF60a Mediates Critical Interactions between Nuclear Receptors and the BRG1 Chromatin-Remodeling Complex for Transactivation , 2003, Molecular and Cellular Biology.

[97]  S. Demo,et al.  Drug discovery in the ubiquitin regulatory pathway. , 2003, Drug discovery today.

[98]  R. Minchin,et al.  Immunophilin chaperones in steroid receptor signalling. , 2003, Current topics in medicinal chemistry.

[99]  E. Soeth,et al.  Inhibition of MMTV transcription by HDAC inhibitors occurs independent of changes in chromatin remodeling and increased histone acetylation , 2003, Oncogene.

[100]  Jeong Hoon Kim,et al.  The roles of protein–protein interactions and protein methylation in transcriptional activation by nuclear receptors and their coactivators , 2003, The Journal of Steroid Biochemistry and Molecular Biology.

[101]  B. O’Malley,et al.  Progesterone and Glucocorticoid Receptors Recruit Distinct Coactivator Complexes and Promote Distinct Patterns of Local Chromatin Modification , 2003 .

[102]  Xi He,et al.  Distinct strategies to make nucleosomal DNA accessible. , 2003, Molecular cell.

[103]  N. Perkins,et al.  P300 transcriptional repression is mediated by SUMO modification. , 2003, Molecular cell.

[104]  J. Cidlowski,et al.  Importance of Ligand Affinity Receptor Mobility in Living Cells : the Molecular Determinants of Glucocorticoid , 2003 .

[105]  D. Picard,et al.  The Hsp90‐binding peptidylprolyl isomerase FKBP52 potentiates glucocorticoid signaling in vivo , 2003, The EMBO journal.

[106]  M. Muratani,et al.  How the ubiquitin–proteasome system controls transcription , 2003, Nature Reviews Molecular Cell Biology.

[107]  W. Pratt,et al.  Regulation of Signaling Protein Function and Trafficking by the hsp90/hsp70-Based Chaperone Machinery 1 , 2003, Experimental biology and medicine.

[108]  Yuanzheng He,et al.  Modulation of Induction Properties of Glucocorticoid Receptor-Agonist and -Antagonist Complexes by Coactivators Involves Binding to Receptors but Is Independent of Ability of Coactivators to Augment Transactivation* , 2002, The Journal of Biological Chemistry.

[109]  R. Hagan,et al.  Effect of Charge Reversal Mutations on the Ligand- and Membrane-binding Properties of Liver Fatty Acid-binding Protein* , 2002, The Journal of Biological Chemistry.

[110]  O. Jänne,et al.  Involvement of Proteasome in the Dynamic Assembly of the Androgen Receptor Transcription Complex* , 2002, The Journal of Biological Chemistry.

[111]  K. Yamamoto,et al.  Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contexts , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[112]  James G McNally,et al.  Dynamic behavior of transcription factors on a natural promoter in living cells , 2002, EMBO reports.

[113]  M. Stallcup,et al.  Requirement for Multiple Domains of the Protein Arginine Methyltransferase CARM1 in Its Transcriptional Coactivator Function* , 2002, The Journal of Biological Chemistry.

[114]  Mingjie Zhang,et al.  Binding of hsp90-associated immunophilins to cytoplasmic dynein: direct binding and in vivo evidence that the peptidylprolyl isomerase domain is a dynein interaction domain. , 2002, Biochemistry.

[115]  O. Jänne,et al.  Small ubiquitin-related modifier-1 (SUMO-1) modification of the glucocorticoid receptor. , 2002, The Biochemical journal.

[116]  D. King,et al.  Largest Subunits of the Human SWI/SNF Chromatin-remodeling Complex Promote Transcriptional Activation by Steroid Hormone Receptors* , 2002, The Journal of Biological Chemistry.

[117]  D. Trouche,et al.  Control of CBP co‐activating activity by arginine methylation , 2002, The EMBO journal.

[118]  S. Kaul,et al.  Mutations at Positions 547–553 of Rat Glucocorticoid Receptors Reveal That hsp90 Binding Requires the Presence, but Not Defined Composition, of a Seven-amino Acid Sequence at the Amino Terminus of the Ligand Binding Domain* , 2002, The Journal of Biological Chemistry.

[119]  W. Pratt,et al.  Nucleotide Binding States of hsp70 and hsp90 during Sequential Steps in the Process of Glucocorticoid Receptor·hsp90 Heterocomplex Assembly* , 2002, The Journal of Biological Chemistry.

[120]  D. Michel,et al.  Potentiation of glucocorticoid receptor transcriptional activity by sumoylation. , 2002, Endocrinology.

[121]  Anjanabha Saha,et al.  Chromatin remodeling by RSC involves ATP-dependent DNA translocation. , 2002, Genes & development.

[122]  A. Yeldandi,et al.  Identification of Protein Arginine Methyltransferase 2 as a Coactivator for Estrogen Receptor α* , 2002, The Journal of Biological Chemistry.

[123]  G. Hager,et al.  Glucocorticoid Receptor Domain Requirements for Chromatin Remodeling and Transcriptional Activation of the Mouse Mammary Tumor Virus Promoter in Different Nucleoprotein Contexts* , 2002, The Journal of Biological Chemistry.

[124]  R. Renkawitz,et al.  RU486-induced Glucocorticoid Receptor Agonism Is Controlled by the Receptor N Terminus and by Corepressor Binding* , 2002, The Journal of Biological Chemistry.

[125]  Eunhee Kim,et al.  Modification of Daxx by small ubiquitin-related modifier-1. , 2002, Biochemical and biophysical research communications.

[126]  T. Willson,et al.  Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition , 2002, Cell.

[127]  A. Cato,et al.  Rapid Actions of Steroid Receptors in Cellular Signaling Pathways , 2002, Science's STKE.

[128]  K. Yamamoto,et al.  Disassembly of Transcriptional Regulatory Complexes by Molecular Chaperones , 2002, Science.

[129]  D. DeFranco,et al.  Proteasomal Inhibition Enhances Glucocorticoid Receptor Transactivation and Alters Its Subnuclear Trafficking , 2002, Molecular and Cellular Biology.

[130]  S. Werner,et al.  A role for endogenous glucocorticoids in wound repair , 2002, EMBO reports.

[131]  Xiaodong Cheng,et al.  Synergy among Nuclear Receptor Coactivators: Selective Requirement for Protein Methyltransferase and Acetyltransferase Activities , 2002, Molecular and Cellular Biology.

[132]  R. Conaway,et al.  Emerging Roles of Ubiquitin in Transcription Regulation , 2002, Science.

[133]  G. Hager,et al.  ATP-Dependent Mobilization of the Glucocorticoid Receptor during Chromatin Remodeling , 2002, Molecular and Cellular Biology.

[134]  S. Fuqua,et al.  Androgen Receptor Acetylation Governs trans Activation and MEKK1-Induced Apoptosis without Affecting In Vitro Sumoylation and trans-Repression Function , 2002, Molecular and Cellular Biology.

[135]  Melissa A. Wilson,et al.  The Histone Deacetylase Inhibitor Trichostatin A Blocks Progesterone Receptor-mediated Transactivation of the Mouse Mammary Tumor Virus Promoter in Vivo * , 2002, The Journal of Biological Chemistry.

[136]  Thomas Kodadek,et al.  Recruitment of a 19S Proteasome Subcomplex to an Activated Promoter , 2002, Science.

[137]  S. Kaul,et al.  Ubc9 Is a Novel Modulator of the Induction Properties of Glucocorticoid Receptors* , 2002, The Journal of Biological Chemistry.

[138]  D. Toft,et al.  HSP40 Binding Is the First Step in the HSP90 Chaperoning Pathway for the Progesterone Receptor* , 2002, The Journal of Biological Chemistry.

[139]  A. Ciechanover,et al.  The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. , 2002, Physiological reviews.

[140]  Cem Elbi,et al.  Protein dynamics in the nuclear compartment. , 2002, Current opinion in genetics & development.

[141]  R. Kingston,et al.  Cooperation between Complexes that Regulate Chromatin Structure and Transcription , 2002, Cell.

[142]  Neil J. McKenna,et al.  Combinatorial Control of Gene Expression by Nuclear Receptors and Coregulators , 2002, Cell.

[143]  T. Kouzarides,et al.  Methylation at arginine 17 of histone H3 is linked to gene activation , 2002, EMBO reports.

[144]  C. Allis,et al.  Hormone-dependent, CARM1-directed, arginine-specific methylation of histone H3 on a steroid-regulated promoter , 2001, Current Biology.

[145]  Keiji Tanaka,et al.  CHIP is a chaperone‐dependent E3 ligase that ubiquitylates unfolded protein , 2001, EMBO reports.

[146]  J. Cidlowski,et al.  Proteasome-mediated Glucocorticoid Receptor Degradation Restricts Transcriptional Signaling by Glucocorticoids* , 2001, The Journal of Biological Chemistry.

[147]  D. Cyr,et al.  CHIP Is a U-box-dependent E3 Ubiquitin Ligase , 2001, The Journal of Biological Chemistry.

[148]  K. Yamamoto,et al.  Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase‐3 response element that mediates regulation by phorbol esters and hormones , 2001, The EMBO journal.

[149]  D. F. Smith,et al.  Overexpression of the FK506-binding immunophilin FKBP51 is the common cause of glucocorticoid resistance in three New World primates. , 2001, General and comparative endocrinology.

[150]  C. Patterson,et al.  Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling , 2001, Current Biology.

[151]  D. Cyr,et al.  From the cradle to the grave: molecular chaperones that may choose between folding and degradation , 2001, EMBO reports.

[152]  B. Wasylyk,et al.  Ligand-dependent interaction of the glucocorticoid receptor with p53 enhances their degradation by Hdm2. , 2001, Genes & development.

[153]  C. Young,et al.  Silymarin inhibits function of the androgen receptor by reducing nuclear localization of the receptor in the human prostate cancer cell line LNCaP. , 2001, Carcinogenesis.

[154]  W. Farrar,et al.  Activation of Estrogen Receptor Blocks Interleukin-6-inducible Cell Growth of Human Multiple Myeloma Involving Molecular Cross-talk between Estrogen Receptor and STAT3 Mediated by Co-regulator PIAS3* , 2001, The Journal of Biological Chemistry.

[155]  C. Allis,et al.  Translating the Histone Code , 2001, Science.

[156]  T. Ishizuka,et al.  Human immunodeficiency virus type 1 Tat binding protein-1 is a transcriptional coactivator specific for TR. , 2001, Molecular endocrinology.

[157]  J. Cidlowski,et al.  Molecular identification and characterization of a and b forms of the glucocorticoid receptor. , 2001, Molecular endocrinology.

[158]  R. Minchin,et al.  Estradiol-regulated expression of the immunophilins cyclophilin 40 and FKBP52 in MCF-7 breast cancer cells. , 2001, Biochemical and biophysical research communications.

[159]  Sergey Belikov,et al.  Hormone‐induced nucleosome positioning in the MMTV promoter is reversible , 2001, The EMBO journal.

[160]  J. Cidlowski,et al.  Proinflammatory cytokines regulate human glucocorticoid receptor gene expression and lead to the accumulation of the dominant negative β isoform: A mechanism for the generation of glucocorticoid resistance , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[161]  T. Kodadek,et al.  The 19S regulatory particle of the proteasome is required for efficient transcription elongation by RNA polymerase II. , 2001, Molecular cell.

[162]  J. Lee,et al.  The Conformation of the Glucocorticoid Receptor AF1/tau1 Domain Induced by Osmolyte Binds Co-regulatory Proteins* , 2001, The Journal of Biological Chemistry.

[163]  C. Allis,et al.  Methylation of Histone H4 at Arginine 3 Facilitating Transcriptional Activation by Nuclear Hormone Receptor , 2001, Science.

[164]  D. Aswad,et al.  Methylation of histone H3 by coactivator-associated arginine methyltransferase 1. , 2001, Biochemistry.

[165]  Lars Packschies,et al.  Tuning of chaperone activity of Hsp70 proteins by modulation of nucleotide exchange , 2001, Nature Structural Biology.

[166]  M. Lazar,et al.  Determinants of CoRNR-Dependent Repression Complex Assembly on Nuclear Hormone Receptors , 2001, Molecular and Cellular Biology.

[167]  Y. Nakatani.  Histone acetylases—versatile players , 2001, Genes to cells : devoted to molecular & cellular mechanisms.

[168]  M. Stallcup,et al.  Synergistic Enhancement of Nuclear Receptor Function by p160 Coactivators and Two Coactivators with Protein Methyltransferase Activities* , 2001, The Journal of Biological Chemistry.

[169]  Shih-Ming Huang,et al.  Synergistic, p160 Coactivator-dependent Enhancement of Estrogen Receptor Function by CARM1 and p300* , 2000, The Journal of Biological Chemistry.

[170]  D. Lilley,et al.  Generation of Superhelical Torsion by ATP-Dependent Chromatin Remodeling Activities , 2000, Cell.

[171]  Myles Brown,et al.  Cofactor Dynamics and Sufficiency in Estrogen Receptor–Regulated Transcription , 2000, Cell.

[172]  Weidong Wang,et al.  A Specificity and Targeting Subunit of a Human SWI/SNF Family-Related Chromatin-Remodeling Complex , 2000, Molecular and Cellular Biology.

[173]  F. Sherman,et al.  Nα-terminal Acetylation of Eukaryotic Proteins* , 2000, The Journal of Biological Chemistry.

[174]  John Calvin Reed,et al.  hsp70 interacting protein Hip does not affect glucocorticoid receptor folding by the hsp90-based chaperone machinery except to oppose the effect of BAG-1. , 2000, Biochemistry.

[175]  David F. Smith,et al.  Printed in U.S.A. Copyright © 2000 by The Endocrine Society Squirrel Monkey Immunophilin FKBP51 Is a Potent Inhibitor of Glucocorticoid Receptor Binding* , 2000 .

[176]  K. Yamamoto,et al.  The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain. , 2000, Genes & development.

[177]  G. Hager,et al.  Structure and Dynamic Properties of a Glucocorticoid Receptor-Induced Chromatin Transition , 2000, Molecular and Cellular Biology.

[178]  P. Sudarsanam,et al.  The Swi/Snf family nucleosome-remodeling complexes and transcriptional control. , 2000, Trends in genetics : TIG.

[179]  J. Iñiguez-Lluhí,et al.  A Common Motif within the Negative Regulatory Regions of Multiple Factors Inhibits Their Transcriptional Synergy , 2000, Molecular and Cellular Biology.

[180]  V. Ogryzko,et al.  p300 and p300/cAMP-response Element-binding Protein-associated Factor Acetylate the Androgen Receptor at Sites Governing Hormone-dependent Transactivation* , 2000, The Journal of Biological Chemistry.

[181]  C. Deng,et al.  The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[182]  B. O’Malley,et al.  The 26S Proteasome Is Required for Estrogen Receptor-α and Coactivator Turnover and for Efficient Estrogen Receptor-α Transactivation , 2000 .

[183]  J. Höhfeld,et al.  Distinct Isoforms of the Cofactor BAG-1 Differentially Affect Hsc70 Chaperone Function* , 2000, The Journal of Biological Chemistry.

[184]  W. V. Berghe,et al.  Glucocorticoids repress NF-kappaB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[185]  J. Workman,et al.  Promoter targeting and chromatin remodeling by the SWI/SNF complex. , 2000, Current opinion in genetics & development.

[186]  J. Workman,et al.  Recruitment of the SWI-SNF Chromatin Remodeling Complex as a Mechanism of Gene Activation by the Glucocorticoid Receptor τ1 Activation Domain , 2000, Molecular and Cellular Biology.

[187]  J. Wong,et al.  p300 Requires Its Histone Acetyltransferase Activity and SRC-1 Interaction Domain To Facilitate Thyroid Hormone Receptor Activation in Chromatin , 2000, Molecular and Cellular Biology.

[188]  J. McNally,et al.  The glucocorticoid receptor: rapid exchange with regulatory sites in living cells. , 2000, Science.

[189]  M. Parker,et al.  Differential interaction of steroid hormone receptors with LXXLL motifs in SRC-1a depends on residues flanking the motif , 2000, The Journal of Steroid Biochemistry and Molecular Biology.

[190]  C. Glass,et al.  The coregulator exchange in transcriptional functions of nuclear receptors. , 2000, Genes & development.

[191]  Martin Rechsteiner,et al.  Recognition of the polyubiquitin proteolytic signal , 2000, The EMBO journal.

[192]  M. Galigniana,et al.  Different Regions of the Immunophilin FKBP52 Determine Its Association with the Glucocorticoid Receptor, hsp90, and Cytoplasmic Dynein* , 1999, The Journal of Biological Chemistry.

[193]  S. Simons,et al.  Opposing effects of corepressor and coactivators in determining the dose-response curve of agonists, and residual agonist activity of antagonists, for glucocorticoid receptor-regulated gene expression. , 1999, Molecular endocrinology.

[194]  R. Shukin,et al.  Determinants of DNA sequence specificity of the androgen, progesterone, and glucocorticoid receptors: evidence for differential steroid receptor response elements. , 1999, Molecular endocrinology.

[195]  M. Galigniana,et al.  A model for the cytoplasmic trafficking of signalling proteins involving the hsp90-binding immunophilins and p50cdc37. , 1999, Cellular signalling.

[196]  M. Lazar,et al.  The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors , 1999, Nature.

[197]  G. Hager,et al.  Using inducible vectors to study intracellular trafficking of GFP-tagged steroid/nuclear receptors in living cells. , 1999, Methods.

[198]  J. Schneikert,et al.  A Nuclear Action of the Eukaryotic Cochaperone Rap46 in Downregulation of Glucocorticoid Receptor Activity , 1999, The Journal of cell biology.

[199]  R. Evans,et al.  Regulation of Hormone-Induced Histone Hyperacetylation and Gene Activation via Acetylation of an Acetylase , 1999, Cell.

[200]  J. Lee,et al.  Interdomain Signaling in a Two-domain Fragment of the Human Glucocorticoid Receptor* , 1999, The Journal of Biological Chemistry.

[201]  D. Aswad,et al.  Regulation of transcription by a protein methyltransferase. , 1999, Science.

[202]  D. Toft,et al.  The Importance of ATP Binding and Hydrolysis by Hsp90 in Formation and Function of Protein Heterocomplexes* , 1999, The Journal of Biological Chemistry.

[203]  P. Connell,et al.  Identification of CHIP, a Novel Tetratricopeptide Repeat-Containing Protein That Interacts with Heat Shock Proteins and Negatively Regulates Chaperone Functions , 1999, Molecular and Cellular Biology.

[204]  J. Reinstein,et al.  Mechanism of regulation of hsp70 chaperones by DnaJ cochaperones. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[205]  R. McMacken,et al.  DnaJ dramatically stimulates ATP hydrolysis by DnaK: insight into targeting of Hsp70 proteins to polypeptide substrates. , 1999, Biochemistry.

[206]  D. DeFranco,et al.  Chromatin recycling of glucocorticoid receptors: implications for multiple roles of heat shock protein 90. , 1999, Molecular endocrinology.

[207]  E. Baulieu,et al.  The molecular chaperone Hsp90 can negatively regulate the activity of a glucocorticosteroid-dependent promoter. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[208]  K. Yamamoto,et al.  An Additional Region of Coactivator GRIP1 Required for Interaction with the Hormone-binding Domains of a Subset of Nuclear Receptors* , 1999, The Journal of Biological Chemistry.

[209]  Chrisostomos Prodromou,et al.  Regulation of Hsp90 ATPase activity by tetratricopeptide repeat (TPR)‐domain co‐chaperones , 1999, The EMBO journal.

[210]  D. F. Smith,et al.  Glucocorticoid resistance in the squirrel monkey is associated with overexpression of the immunophilin FKBP51. , 1999, The Journal of clinical endocrinology and metabolism.

[211]  R. Kingston,et al.  Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits. , 1999, Molecular cell.

[212]  David F. Smith,et al.  Hop as an Adaptor in the Heat Shock Protein 70 (Hsp70) and Hsp90 Chaperone Machinery* , 1998, The Journal of Biological Chemistry.

[213]  M. Welsh,et al.  Heat shock protein 90-dependent (geldanamycin-inhibited) movement of the glucocorticoid receptor through the cytoplasm to the nucleus requires intact cytoskeleton. , 1998, Molecular endocrinology.

[214]  J. Song,et al.  BAG‐1, a negative regulator of Hsp70 chaperone activity, uncouples nucleotide hydrolysis from substrate release , 1998, The EMBO journal.

[215]  C. Glass,et al.  Nuclear Integration of Glucocorticoid Receptor and Nuclear Factor-κB Signaling by CREB-binding Protein and Steroid Receptor Coactivator-1* , 1998, The Journal of Biological Chemistry.

[216]  R. Melki,et al.  The Chaperone Cofactor Hop/p60 Interacts with the Cytosolic Chaperonin-containing TCP-1 and Affects Its Nucleotide Exchange and Protein Folding Activities* , 1998, The Journal of Biological Chemistry.

[217]  T. Yamamoto,et al.  Crosstalk between the interleukin-6 (IL-6)-JAK-STAT and the glucocorticoid-nuclear receptor pathway: synergistic activation of IL-6 response element by IL-6 and glucocorticoid. , 1998, The Journal of endocrinology.

[218]  Tae Hoon Kim,et al.  Efficient recruitment of TFIIB and CBP-RNA polymerase II holoenzyme by an interferon-beta enhanceosome in vitro. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[219]  L. Pearl,et al.  ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo , 1998, The EMBO journal.

[220]  W. Pratt,et al.  Studies with Purified Chaperones Advance the Understanding of the Mechanism of Glucocorticoid Receptor–hsp90 Heterocomplex Assembly , 1998, Trends in Endocrinology & Metabolism.

[221]  Jun Qin,et al.  Histone-like TAFs within the PCAF Histone Acetylase Complex , 1998, Cell.

[222]  J. Gustafsson,et al.  Role of important hydrophobic amino acids in the interaction between the glucocorticoid receptor tau 1-core activation domain and target factors. , 1998, Biochemistry.

[223]  M. Garabedian,et al.  Phosphorylation and Inhibition of Rat Glucocorticoid Receptor Transcriptional Activation by Glycogen Synthase Kinase-3 (GSK-3) , 1998, The Journal of Biological Chemistry.

[224]  K. Kaestner,et al.  DNA Binding of the Glucocorticoid Receptor Is Not Essential for Survival , 1998, Cell.

[225]  D. Edwards,et al.  The Steroid Receptor Coactivator-1 Contains Multiple Receptor Interacting and Activation Domains That Cooperatively Enhance the Activation Function 1 (AF1) and AF2 Domains of Steroid Receptors* , 1998, The Journal of Biological Chemistry.

[226]  T. Archer,et al.  Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex , 1998, Nature.

[227]  Jeffrey A. Lefstin,et al.  Allosteric effects of DNA on transcriptional regulators , 1998, Nature.

[228]  J. Cidlowski,et al.  Glucocorticoid receptor phosphorylation: Overview, function and cell cycle-dependence 1 1 Proceedings of the 13th International Symposium of the Journal of Steroid Biochemistry & Molecular Biology “Recent Advances in Steroid Biochemistry & Molecular Biology” Monaco 25–28 May 1997. , 1998, The Journal of Steroid Biochemistry and Molecular Biology.

[229]  B. O’Malley,et al.  Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene. , 1998, Science.

[230]  M. Stallcup,et al.  Nuclear receptor-binding sites of coactivators glucocorticoid receptor interacting protein 1 (GRIP1) and steroid receptor coactivator 1 (SRC-1): multiple motifs with different binding specificities. , 1998, Molecular endocrinology.

[231]  C. Glass,et al.  Transcription factor-specific requirements for coactivators and their acetyltransferase functions. , 1998, Science.

[232]  H. Gronemeyer,et al.  The coactivator TIF2 contains three nuclear receptor‐binding motifs and mediates transactivation through CBP binding‐dependent and ‐independent pathways , 1998, The EMBO journal.

[233]  U. Gehring,et al.  Proteins interacting with the molecular chaperone hsp70/hsc70: physical associations and effects on refolding activity , 1997, FEBS letters.

[234]  N. Koibuchi,et al.  TRAM-1, A Novel 160-kDa Thyroid Hormone Receptor Activator Molecule, Exhibits Distinct Properties from Steroid Receptor Coactivator-1* , 1997, The Journal of Biological Chemistry.

[235]  J. Drouin,et al.  Antagonism between Nur77 and glucocorticoid receptor for control of transcription , 1997, Molecular and cellular biology.

[236]  W. Pratt,et al.  Folding of the Glucocorticoid Receptor by the Heat Shock Protein (hsp) 90-based Chaperone Machinery , 1997, The Journal of Biological Chemistry.

[237]  P. Meltzer,et al.  AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer. , 1997, Science.

[238]  R. Evans,et al.  Nuclear Receptor Coactivator ACTR Is a Novel Histone Acetyltransferase and Forms a Multimeric Activation Complex with P/CAF and CBP/p300 , 1997, Cell.

[239]  Hui Li,et al.  RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[240]  J. Gustafsson,et al.  Glucocorticoid-dependent transcriptional repression of the osteocalcin gene by competitive binding at the TATA box. , 1997, DNA and cell biology.

[241]  B. Segnitz,et al.  The Function of Steroid Hormone Receptors Is Inhibited by the hsp90-specific Compound Geldanamycin* , 1997, The Journal of Biological Chemistry.

[242]  L. Pearl,et al.  Identification and Structural Characterization of the ATP/ADP-Binding Site in the Hsp90 Molecular Chaperone , 1997, Cell.

[243]  B. Groner,et al.  Epithelial Cells. Mammary Stat5 and Stat6 in Lymphoid Cells and Comparison of the Transactivation Domains Of , 1997 .

[244]  K. Yamamoto,et al.  Mitogen-activated and cyclin-dependent protein kinases selectively and differentially modulate transcriptional enhancement by the glucocorticoid receptor , 1997, Molecular and cellular biology.

[245]  B. van der Burg,et al.  Novel Progesterone Target Genes Identified by an Improved Differential Display Technique Suggest That Progestin-induced Growth Inhibition of Breast Cancer Cells Coincides with Enhancement of Differentiation* , 1997, The Journal of Biological Chemistry.

[246]  Christopher K. Glass,et al.  The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function , 1997, Nature.

[247]  David M. Heery,et al.  A signature motif in transcriptional co-activators mediates binding to nuclear receptors , 1997, Nature.

[248]  W. Pratt,et al.  Steroid receptor interactions with heat shock protein and immunophilin chaperones. , 1997, Endocrine reviews.

[249]  S. Schreiber,et al.  Nuclear Receptor Repression Mediated by a Complex Containing SMRT, mSin3A, and Histone Deacetylase , 1997, Cell.

[250]  C. Glass,et al.  A complex containing N-CoR, mSln3 and histone deacetylase mediates transcriptional repression , 1997, nature.

[251]  M. Martin,et al.  Tissue distribution and abundance of human FKBP51, and FK506-binding protein that can mediate calcineurin inhibition. , 1997, Biochemical and biophysical research communications.

[252]  O. Wrange,et al.  Glucocorticoid receptor-glucocorticoid response element binding stimulates nucleosome disruption by the SWI/SNF complex , 1997, Molecular and cellular biology.

[253]  G. Duff,et al.  A negative regulatory region containing a glucocorticosteroid response element (nGRE) in the human interleukin-1beta gene. , 1997, DNA and cell biology.

[254]  Andrew J. Bannister,et al.  The CBP co-activator is a histone acetyltransferase , 1996, Nature.

[255]  B. Howard,et al.  The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases , 1996, Cell.

[256]  B. Groner,et al.  Functional interactions between Stat5 and the glucocorticoid receptor , 1996, Nature.

[257]  M. Beato,et al.  Moderate increase in histone acetylation activates the mouse mammary tumor virus promoter and remodels its nucleosome structure. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[258]  B. Howard,et al.  A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A , 1996, Nature.

[259]  P. Chambon,et al.  TIF2, a 160 kDa transcriptional mediator for the ligand‐dependent activation function AF‐2 of nuclear receptors. , 1996, The EMBO journal.

[260]  L. Whitesell,et al.  Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cells. , 1996, Molecular endocrinology.

[261]  K. Yamamoto,et al.  Intracellular receptors use a common mechanism to interpret signaling information at response elements. , 1996, Genes & development.

[262]  M. Stallcup,et al.  GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[263]  K. Umesono,et al.  The nuclear receptor superfamily: The second decade , 1995, Cell.

[264]  B. O’Malley,et al.  Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily , 1995, Science.

[265]  F. Hartl,et al.  Hip, a novel cochaperone involved in the eukaryotic hsc70/hsp40 reaction cycle , 1995, Cell.

[266]  M. Welsh,et al.  Evidence that the FK506-binding immunophilin heat shock protein 56 is required for trafficking of the glucocorticoid receptor from the cytoplasm to the nucleus. , 1995, Molecular endocrinology.

[267]  Thorsten Heinzel,et al.  Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor , 1995, Nature.

[268]  K. Dahlman-Wright,et al.  Structural characterization of a minimal functional transactivation domain from the human glucocorticoid receptor. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[269]  M. Welsh,et al.  The hsp56 immunophilin component of untransformed steroid receptor complexes is localized both to microtubules in the cytoplasm and to the same nonrandom regions within the nucleus as the steroid receptor. , 1994, Molecular endocrinology.

[270]  P. Herrlich,et al.  A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP‐1. , 1994, The EMBO journal.

[271]  J. Gustafsson,et al.  Refined solution structure of the glucocorticoid receptor DNA-binding domain. , 1994, Biochemistry.

[272]  A. Ray,et al.  Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[273]  M. Yaniv,et al.  A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor. , 1993, The EMBO journal.

[274]  D. DeFranco,et al.  Bidirectional transport of glucocorticoid receptors across the nuclear envelope. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[275]  D. Edwards,et al.  The constitution of a progesterone response element. , 1993, Molecular endocrinology.

[276]  J. Drouin,et al.  Novel glucocorticoid receptor complex with DNA element of the hormone‐repressed POMC gene. , 1993, The EMBO journal.

[277]  I. Herskowitz,et al.  Roles of SWI1, SWI2, and SWI3 proteins for transcriptional enhancement by steroid receptors. , 1992, Science.

[278]  P. Herrlich,et al.  Interference between pathway‐specific transcription factors: glucocorticoids antagonize phorbol ester‐induced AP‐1 activity without altering AP‐1 site occupation in vivo. , 1992, The EMBO journal.

[279]  K. Dahlman-Wright,et al.  Zinc coordination scheme for the C-terminal zinc binding site of nuclear hormone receptors , 1992, The Journal of Steroid Biochemistry and Molecular Biology.

[280]  G. Hager,et al.  Transcription factor loading on the MMTV promoter: a bimodal mechanism for promoter activation. , 1992, Science.

[281]  A. Reik,et al.  Glucocorticoids are required for establishment and maintenance of an alteration in chromatin structure: induction leads to a reversible disruption of nucleosomes over an enhancer. , 1991, The EMBO journal.

[282]  L. Poellinger,et al.  The glucocorticoid receptor binds to a sequence overlapping the TATA box of the human osteocalcin promoter: a potential mechanism for negative regulation , 1991, Molecular and cellular biology.

[283]  R. Evans,et al.  Heat shock protein 90 as a critical factor in maintaining glucocorticosteroid receptor in a nonfunctional state. , 1991, The Journal of biological chemistry.

[284]  J. Gustafsson,et al.  DNA‐Binding Specificity of Mutant Glucocorticoid Receptor DNA‐Binding Domains , 1991, Annals of the New York Academy of Sciences.

[285]  K. Dahlman-Wright,et al.  Interaction of the glucocorticoid receptor DNA-binding domain with DNA as a dimer is mediated by a short segment of five amino acids. , 1991, The Journal of biological chemistry.

[286]  G. Hager,et al.  Transcription factor access is mediated by accurately positioned nucleosomes on the mouse mammary tumor virus promoter , 1991, Molecular and cellular biology.

[287]  S. Meshinchi,et al.  Structural and functional reconstitution of the glucocorticoid receptor-hsp90 complex. , 1990, The Journal of biological chemistry.

[288]  C. Hutchison,et al.  Structural determinants of a glucocorticoid receptor recognition element. , 1990, Molecular endocrinology.

[289]  S. Kliewer,et al.  Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor , 1990, Cell.

[290]  K. Yamamoto,et al.  Solution structure of the glucocorticoid receptor DNA-binding domain. , 1990, Science.

[291]  J. Gustafsson,et al.  Cooperativity and specificity in the interactions between DNA and the glucocorticoid receptor DNA-binding domain. , 1990, Biochemistry.

[292]  J. Gustafsson,et al.  The transformed glucocorticoid receptor has a lower steroid-binding affinity than the nontransformed receptor. , 1990, Biochemistry.

[293]  R. Evans,et al.  Multiple and cooperative trans-activation domains of the human glucocorticoid receptor , 1988, Cell.

[294]  W. Pratt,et al.  Localization of phosphorylation sites with respect to the functional domains of the mouse L cell glucocorticoid receptor. , 1988, The Journal of biological chemistry.

[295]  K. Yamamoto,et al.  The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain , 1988, Nature.

[296]  R. Harrison,et al.  Glucocorticoid receptor phosphorylation, transformation, and DNA binding. , 1987, The Journal of biological chemistry.

[297]  J. Jonklaas,et al.  Domains of the glucocorticoid receptor involved in specific and nonspecific deoxyribonucleic acid binding, hormone activation, and transcriptional enhancement. , 1987, Molecular endocrinology.

[298]  H. Richard-Foy,et al.  Sequence‐specific positioning of nucleosomes over the steroid‐inducible MMTV promoter. , 1987, The EMBO journal.

[299]  K. Yamamoto,et al.  Functional dissection of the hormone and DNA binding activities of the glucocorticoid receptor. , 1987, The EMBO journal.

[300]  R. Evans,et al.  Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor , 1987, Cell.

[301]  S. Rogers,et al.  Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis. , 1986, Science.

[302]  R. Evans,et al.  Functional domains of the human glucocorticoid receptor , 1986, Cell.

[303]  P Argos,et al.  The chicken oestrogen receptor sequence: homology with v‐erbA and the human oestrogen and glucocorticoid receptors. , 1986, The EMBO journal.

[304]  S. Jacob,et al.  Phosphorylation of purified glucocorticoid receptor from rat liver by an endogenous protein kinase. , 1984, Biochemical and biophysical research communications.

[305]  K. Yamamoto,et al.  DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo , 1983, Cell.

[306]  E. Thompson,et al.  Dexamethasone 21-mesylate: an affinity label of glucocorticoid receptors from rat hepatoma tissue culture cells. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[307]  W. Pratt,et al.  Evidence that dephosphorylation inactivates glucocorticoid receptors. , 1977, Proceedings of the National Academy of Sciences of the United States of America.

[308]  A. Munck,et al.  Kinetics of glucocorticoid-receptor complexes in rat thymus cells. , 1976, Journal of steroid biochemistry.

[309]  G. Hager,et al.  Dynamic access of the glucocorticoid receptor to response elements in chromatin. , 2009, The international journal of biochemistry & cell biology.

[310]  F. Grosveld,et al.  Beta-globin regulation and long-range interactions. , 2008, Advances in genetics.

[311]  W. Pratt,et al.  Chaperoning of glucocorticoid receptors. , 2006, Handbook of experimental pharmacology.

[312]  G. Hager,et al.  Transcription Factor Dynamics , 2006 .

[313]  L. Neckers,et al.  Geldanamycin as a Potential Anti-Cancer Agent: Its Molecular Target and Biochemical Activity , 2004, Investigational New Drugs.

[314]  David F. Smith.  Tetratricopeptide repeat cochaperones in steroid receptor complexes , 2004, Cell stress & chaperones.

[315]  Holly McDonough,et al.  CHIP: a link between the chaperone and proteasome systems , 2003, Cell stress & chaperones.

[316]  J. Mullol,et al.  Expression of the human glucocorticoid receptor alpha and beta isoforms in human respiratory epithelial cells and their regulation by dexamethasone. , 2001, American journal of respiratory cell and molecular biology.

[317]  G. Hager.  Understanding nuclear receptor function: from DNA to chromatin to the interphase nucleus. , 2001, Progress in nucleic acid research and molecular biology.

[318]  P. Connell,et al.  The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins , 2000, Nature Cell Biology.

[319]  D. DeFranco,et al.  Assessment of glucocorticoid receptor-heat shock protein 90 interactions in vivo during nucleocytoplasmic trafficking. , 1996, Molecular endocrinology.

[320]  D. Toft,et al.  Steroid receptors and their associated proteins. , 1993, Molecular endocrinology.

[321]  R. Roeder,et al.  The complexities of eukaryotic transcription initiation: regulation of preinitiation complex assembly. , 1991, Trends in biochemical sciences.

[322]  A. Munck,et al.  A dynamic model of glucocorticoid receptor phosphorylation and cycling in intact cells. , 1989, Journal of steroid biochemistry.

[323]  E. R. Sánchez,et al.  Glucocorticoid receptor phosphorylation in mouse L-cells. , 1987, Journal of steroid biochemistry.