Calcium Channel Blockers and the Risk of Cancer: A Preclinical Assessment
暂无分享,去创建一个
G. Schlüter | H. Ahr | E. Karbe | H. Enzmann | E. Bomhard | H. Mager | E. Sander
[1] H. Jick. Calcium-channel blockers and risk of cancer , 1997, The Lancet.
[2] J. Olsen,et al. Cancer risk in users of calcium channel blockers. , 1997, Hypertension.
[3] R. Collins,et al. Effects of calcium antagonists on the risks of coronary heart disease, cancer and bleeding , 1997, Journal of Human Hypertension.
[4] J. Barrett,et al. Effects of alterations in calcium homeostasis on apoptosis during neoplastic progression. , 1997, Cancer research.
[5] Morris J. Brown. Calcium-channel blockers and cancer , 1996, The Lancet.
[6] R. Roberts,et al. Species differences in response to peroxisome proliferators correlate in vitro with induction of DNA synthesis rather than suppression of apoptosis. , 1996, Carcinogenesis.
[7] H. Iishi,et al. Inhibition by verapamil of cholecystokinin-enhancement of pancreatic carcinogenesis induced by azaserine in Wistar rats. , 1996, Cancer letters.
[8] J. Guralnik,et al. Do calcium channel blockers increase the risk of cancer? , 1996, American journal of hypertension.
[9] A. Balakumaran,et al. Calcium channel blockers induce thymic apoptosis in vivo in rats. , 1996, Toxicology and applied pharmacology.
[10] E. Ritz,et al. Inhibitory effect of calcium channel blockers on human mesangial cell growth: evidence for actions independent of L-type Ca2+ channels. , 1996, Kidney international.
[11] A. Monro. Are lifespan rodent carcinogenicity studies defensible for pharmaceutical agents? , 1996, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
[12] G. Williams,et al. Chemical carcinogen mechanisms of action and implications for testing methodology. , 1996, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
[13] T. Loh,et al. Roles of calcium in the regulation of apoptosis in HL-60 promyelocytic leukemia cells. , 1995, Life sciences.
[14] V. Soldatenkov,et al. The effect of hyperthermia and verapamil on primary and metastatic colon adenocarcinoma cell-lines - inhibition of proliferation, cell-cycle distribution and onset of apoptosis. , 1995, Oncology reports.
[15] S. Eto,et al. Stimulatory Effect of Interleukin‐1α on Proliferation through a Ca2+/Calmodulindependent Pathway of a Human Thyroid Carcinoma Cell Line, NIM 1 , 1995, Japanese journal of cancer research : Gann.
[16] M. Berridge,et al. Calcium signalling and cell proliferation , 1995, BioEssays : news and reviews in molecular, cellular and developmental biology.
[17] S. Orrenius,et al. Apoptosis: molecular mechanisms and implications for human disease , 1995, Journal of internal medicine.
[18] F. Chisari,et al. Strong, sustained hepatocellular proliferation precedes hepatocarcinogenesis in hepatitis B surface antigen transgenic mice , 1995, Hepatology.
[19] W. Zhou,et al. Calcium, calmodulin and cell cycle progression. , 1995, Cellular signalling.
[20] B. Robinson. Molecular genetics of thyroid and parathyroid neoplasia. , 1995, The Australian and New Zealand journal of surgery.
[21] R. Jensen,et al. In Vitro Growth Inhibition of Growth Factor-stimulated Meningioma Cells by Calcium Channel Antagonists , 1995 .
[22] Dariusz Leszczyński,et al. Apoptosis of vascular smooth muscle cells. Protein kinase C and oncoprotein Bcl-2 are involved in regulation of apoptosis in non-transformed rat vascular smooth muscle cells. , 1994, The American journal of pathology.
[23] J. Simard,et al. Inverse relationships between cell proliferation and basal or androgen-stimulated apolipoprotein D secretion in LNCaP human prostate cancer cells , 1994, The Journal of Steroid Biochemistry and Molecular Biology.
[24] A. Nyska,et al. Constipation and Megacolon in Rats Related to Treatment with Oxodipine, a Calcium Antagonist , 1994, Toxicologic pathology.
[25] S. Orrenius,et al. Signal transduction pathways in apoptosis. , 1994, Stem cells.
[26] P. Nicotera,et al. Apoptosis: molecular control point in toxicity. , 1994, Toxicology and applied pharmacology.
[27] R. Kluck,et al. Calcium chelators induce apoptosis--evidence that raised intracellular ionised calcium is not essential for apoptosis. , 1994, Biochimica et biophysica acta.
[28] H C Pitot,et al. Incorporation of bromodeoxyuridine in glutathione S-transferase-positive hepatocytes during rat multistage hepatocarcinogenesis. , 1994, Carcinogenesis.
[29] B. Hulka,et al. Steroid hormones and risk of breast cancer , 1994, Cancer.
[30] Y. Lee,et al. Inhibition of cell growth and intracellular Ca2+ mobilization in human brain tumor cells by Ca2+ channel antagonists. , 1994, Molecular and chemical neuropathology.
[31] J. Larrick,et al. Inhibition of apoptosis as a mechanism of tumor promotion , 1994, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[32] M. Deltenre,et al. Helicobacter pylori: the link with gastric cancer. , 1994, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.
[33] S. Singh,et al. Potentiation of tamoxifen activity by verapamil in a human breast cancer cell line. , 1994, Biochemical pharmacology.
[34] B. Hogan,et al. Acceleration of mammary neoplasia in transforming growth factor alpha transgenic mice by 7,12-dimethylbenzanthracene. , 1994, Cancer research.
[35] U. Thorgeirsson,et al. Tumor incidence in a chemical carcinogenesis study of nonhuman primates. , 1994, Regulatory toxicology and pharmacology : RTP.
[36] E. Kohn,et al. Calcium-mediated signal transduction: biology, biochemistry, and therapy , 1994, Cancer and Metastasis Reviews.
[37] C. Capen,et al. Neoplastic Lesions of Questionable Significance to Humans , 1994, Toxicologic pathology.
[38] E. Bomhard,et al. Frequency of spontaneous tumours in Wistar rats in 2-year studies. , 1994, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
[39] D. Chung,et al. Inhibitory Effect of Calcium Channel Blockers on Growth of Pancreatic Cancer Cells , 1994, Pancreas.
[40] M. Rosin,et al. Involvement of inflammatory reactions and elevated cell proliferation in the development of bladder cancer in schistosomiasis patients. , 1994, Mutation research.
[41] L. Pradayrol,et al. Inhibition of gastrin‐induced proliferation of AR4–2j cells by calcium channel antagonists , 1994, International journal of cancer.
[42] M. Berridge. The biology and medicine of calcium signalling , 1994, Molecular and Cellular Endocrinology.
[43] I. Purchase. Current Knowledge of Mechanisms of Carcinogenicity: Genotoxins versus Non-genotoxins , 1994, Human & experimental toxicology.
[44] E. Sher,et al. Calcium channel subtypes controlling serotonin release from human small cell lung carcinoma cell lines. , 1993, The Journal of biological chemistry.
[45] B. Short. Cell proliferation and renal carcinogenesis. , 1993, Environmental health perspectives.
[46] R. G. Croy. Role of chemically induced cell proliferation in carcinogenesis and its use in health risk assessment. , 1993, Environmental health perspectives.
[47] L. Tomatis. Cell proliferation and carcinogenesis. A brief history and current view based on IARC Workshop report , 1993 .
[48] L. Tomatis. Cell proliferation and carcinogenesis: a brief history and current view based on an IARC workshop report. International Agency for Research on Cancer. , 1993, Environmental health perspectives.
[49] D. Parkin,et al. Cholangiocarcinoma: epidemiology, mechanisms of carcinogenesis and prevention. , 1993, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[50] P. Rorsman,et al. Increased activity of L-type Ca2+ channels exposed to serum from patients with type I diabetes. , 1993, Science.
[51] C. Haslett,et al. Transient elevations of cytosolic free calcium retard subsequent apoptosis in neutrophils in vitro. , 1993, The Journal of clinical investigation.
[52] D. Carson,et al. Apoptosis and disease , 1993, The Lancet.
[53] G. Dubyak,et al. Effect of glucocorticosteroid treatment on intracellular calcium homeostasis in mouse lymphoma cells. , 1993, Molecular endocrinology.
[54] A. Means,et al. Regulation of the cell cycle by calcium and calmodulin. , 1993, Endocrine reviews.
[55] M. Piontek,et al. Effect of calcium-modifying agents on the growth of human gastric carcinoma cells in vitro. , 1992, Anticancer research.
[56] J. Taylor,et al. Inhibition of cancer cell growth by calcium channel antagonists in the athymic mouse. , 1992, Cancer research.
[57] T. Cotter,et al. Elevations in cytosolic free Ca2+ are not required to trigger apoptosis in human leukaemia cells , 1992, Clinical and experimental immunology.
[58] M. Collins,et al. Inhibition of apoptosis by calcium ionophores in IL-3-dependent bone marrow cells is dependent upon production of IL-4+. , 1992, Journal of immunology.
[59] Gwyn T. Williams. Programmed cell death: Apoptosis and oncogenesis , 1991, Cell.
[60] P. Grasso,et al. Evidence for and possible mechanisms of non-genotoxic carcinogenesis in rodent liver. , 1991, Mutation research.
[61] W. Colucci,et al. Calcium influx modulates DNA synthesis and proliferation in A7r5 vascular smooth muscle cells. , 1991, European Journal of Pharmacology.
[62] J. K. Bubien,et al. Transmembrane ion conductance in human B lymphocyte activation. , 1990, Journal of immunology.
[63] S. Orrenius,et al. Receptor-operated calcium influx in rat hepatocytes. Identification and characterization using manganese. , 1990, The Journal of biological chemistry.
[64] E. Alnemri,et al. Activation of internucleosomal DNA cleavage in human CEM lymphocytes by glucocorticoid and novobiocin. Evidence for a non-Ca2(+)-requiring mechanism(s). , 1990, The Journal of biological chemistry.
[65] B. Ames,et al. Too many rodent carcinogens: mitogenesis increases mutagenesis. , 1990, Science.
[66] W. Bursch,et al. DNA synthesis, apoptosis, and phenotypic expression as determinants of growth of altered foci in rat liver during phenobarbital promotion. , 1990, Cancer research.
[67] H. Iishi,et al. Effect of calcium channel blockers on gastric carcinogenesis and caerulein enhancement of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats. , 1990, Cancer research.
[68] M. D. Hogan,et al. The impact of toxicity on carcinogenicity studies: implications for risk assessment. , 1988, Carcinogenesis.
[69] W. F. Schmidt,et al. Antiproliferative effect of verapamil alone on brain tumor cells in vitro. , 1988, Cancer research.
[70] D. Krewski,et al. Statistical Methods in Cancer Research: Volume III: The Design and Analysis of Long-Term Animal Experiments , 1987 .
[71] T. Okazaki,et al. Role of intracellular calcium ion in human promyelocytic leukemia HL-60 cell differentiation. , 1986, Cancer research.
[72] D. Handley,et al. Suppression of rat carotid lesion development by the calcium channel blocker PN 200-110. , 1986, The American journal of pathology.
[73] S. Eto,et al. Calcium dependency in the growth of adult T-cell leukemia cells in vitro. , 1986, Cancer research.
[74] N. Colburn,et al. Extracellular calcium requirement for promotion of transformation in JB6 cells. , 1986, Cancer research.
[75] L. Ryan. Efficiency of age-adjusted tests in animal carcinogenicity experiments. , 1985, Biometrics.
[76] W. Bursch,et al. Controlled death (apoptosis) of normal and putative preneoplastic cells in rat liver following withdrawal of tumor promoters. , 1984, Carcinogenesis.
[77] Kenneth Wright,et al. Letter to the editor , 1967, Commun. ACM.
[78] J. Tímár,et al. Calcium channel blocker treatment of tumor cells induces alterations in the cytoskeleton, mobility of the integrin αIIbβ3 and tumor-cell-induced platelet aggregation , 2005, Journal of Cancer Research and Clinical Oncology.
[79] Ø. Bruserud,et al. In vitro effect of r-verapamil on acute myelogenous leukemia blast cells: studies of cytokine secretion and cytokine-dependent blast proliferation , 2004, Cancer Chemotherapy and Pharmacology.
[80] Gerald LitwackS. Activation of Internucleosomal DNA Cleavage in Human CEM Lymphocytes by Glucocorticoid and Novobiocin , 2001 .
[81] 井口 信夫. Stimulatory effect of interleukin-1α on proliferation through a Ca[2+]/calmodulin-dependent pathway of a human thyroid carcinoma cell line, NIM 1 , 1996 .
[82] D. Dr. Calcium regulation of apoptosis. , 1995 .
[83] D. Dowd. Calcium regulation of apoptosis. , 1995, Advances in second messenger and phosphoprotein research.
[84] J. DiGiovanni,et al. Role of the epidermal growth factor receptor and transforming growth factor alpha in mouse skin carcinogenesis. , 1994 .
[85] E. Bomhard. Frequency of spontaneous tumours in NMRI mice in 21-month studies. , 1993, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
[86] W. Bursch,et al. Cell death by apoptosis and its protective role against disease. , 1992, Trends in pharmacological sciences.
[87] J. Whitfield. Calcium signals and cancer. , 1992, Critical reviews in oncogenesis.
[88] Whitfield Jf. Calcium signals and cancer. , 1992 .
[89] T. Grogan,et al. P-glycoprotein expression in malignant lymphoma and reversal of clinical drug resistance with chemotherapy plus high-dose verapamil. , 1991, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[90] Thomas E. Moritz,et al. Chronic calcium antagonist use in carcinoma of the lung and colon: a retrospective cohort observational study. , 1990, Cancer investigation.
[91] T. Sladek,et al. Antimetastatic action of diltiazem on LS/BL tumor cells in liver tumor-colony assay. , 1990, Neoplasma.
[92] J. Isaacs,et al. Role of calcium in the programmed death of rat prostatic glandular cells , 1990, The Prostate.
[93] M. Pawlikowski,et al. Involvement of calcium channels in control of the pituitary tumoral cell proliferation in vitro , 1989 .
[94] M. Benson,et al. Calcium channel antagonists delay regression of androgen‐dependent tissues and suppress gene activity associated with cell death , 1988, The Prostate.
[95] C. Ra,et al. Ultrastructural effects of DDT on cells grown in vitro. , 1987 .
[96] E. Karbe,et al. Spontaneous tumors of 2000 Wistar TNO/W.70 rats in two-year carcinogenicity studies. , 1986, Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer.
[97] S. Grinstein,et al. Characterization of the role for calcium influx in mitogen‐induced triggering of human T cells. Identification of calcium‐dependent and calcium‐independent signals , 1986, European journal of immunology.
[98] B. Klein,et al. Early events in human B cell activation: metabolic pathways vary according to the first signal used , 1986, European journal of immunology.
[99] T. Vanaman,et al. Calcium and calmodulin in cell growth and transformation. , 1984, Biochimica et biophysica acta.
[100] Bonnie F. Sloane,et al. Calcium Channel Blockers: Inhibitors of Tumor Cell-Platelet-Endothelial Cell Interactions , 1984 .
[101] J Wahrendorf,et al. Guidelines for simple, sensitive significance tests for carcinogenic effects in long-term animal experiments. , 1980, IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans. Supplement.