Myelofibrosis and tuberculosis caused by atypical mycobacteria.

A case of myelofibrosis associated with pulmonary tuberculosis, caused by atypical organisms, is reported. Both diseases were present at the time of discovery; there was no history of exposure to benzene or irradiation. Antimicrobial therapy had no effect on the myelofibrsis, and the mycobacterial disease process showed stability, with no evidence of involvement of the spleen or lymph glands, or terminal miliary spread. This case, to our knowledge, is the first one in which coexistence of myelofibrosis and mycobacteriosis caused by atypical (Group 1) organisms has been reported. Causal relationship between these two diseases could not be established in this patient.