Effect of chemical linkage upon the stability and cytotoxic activity of A chain immunotoxins.
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[1] D. Blakey,et al. New coupling agents for the synthesis of immunotoxins containing a hindered disulfide bond with improved stability in vivo. , 1987, Cancer research.
[2] D. Blakey,et al. Comparison of two anti-Thy 1.1-abrin A-chain immunotoxins prepared with different cross-linking agents: antitumor effects, in vivo fate, and tumor cell mutants. , 1987, Journal of the National Cancer Institute.
[3] D. Blakey,et al. Effect of chemical deglycosylation of ricin A chain on the in vivo fate and cytotoxic activity of an immunotoxin composed of ricin A chain and anti-Thy 1.1 antibody. , 1987, Cancer research.
[4] C. Vogel. Immunoconjugates : antibody conjugates in radioimaging and therapy of cancer , 1987 .
[5] W. A. Stevens,et al. Bryodin, a ribosome-inactivating protein from the roots of Bryonia dioica L. (white bryony). , 1986, The Biochemical journal.
[6] W. Ross,et al. Effect of linkage variation on pharmacokinetics of ricin A chain-antibody conjugates in normal rats. , 1986, Anti-cancer drug design.
[7] J. Ritz,et al. In vivo administration of lymphocyte-specific monoclonal antibodies in nonhuman primates. In vivo stability of disulfide-linked immunotoxin conjugates. , 1986, The Journal of clinical investigation.
[8] W. Ross,et al. Fate of an antibody-ricin A chain conjugate administered to normal rats. , 1986, Biochemical pharmacology.
[9] P. Casellas,et al. Study of the plasma clearance of antibody--ricin-A-chain immunotoxins. Evidence for specific recognition sites on the A chain that mediate rapid clearance of the immunotoxin. , 1986, European journal of biochemistry.
[10] L. Barbieri,et al. Ribosome‐inactivating proteins up to date , 1986, FEBS letters.
[11] D. Blakey,et al. Effect of chemical deglycosylation on the in vivo fate of ricin A-chain. , 1986, Cancer drug delivery.
[12] A. Yau-Young,et al. Purified immunotoxins that are reactive with human lymphoid cells. Monoclonal antibodies conjugated to the ribosome-inactivating proteins gelonin and the pokeweed antiviral proteins. , 1985, The Journal of biological chemistry.
[13] P. Gros,et al. Biochemical aspects of immunotoxin preparation. , 1985, Journal of immunological methods.
[14] F. Stirpe,et al. An immunotoxin composed of monoclonal anti-Thy 1.1 antibody and a ribosome-inactivating protein from Saponaria officinalis: potent antitumor effects in vitro and in vivo. , 1985, Journal of the National Cancer Institute.
[15] S. Ramakrishnan,et al. Immunological and biological stability of immunotoxins in vivo as studied by the clearance of disulfide-linked pokeweed antiviral protein-antibody conjugates from blood. , 1985, Cancer research.
[16] B. Foxwell,et al. [16] Preparation of antibody—toxin conjugates , 1985 .
[17] C. Vogel,et al. In vivo studies with covalent conjugates of cobra venom factor and monoclonal antibodies to human tumors. , 1985, Haematology and blood transfusion.
[18] K. M. Hwang,et al. Selective antitumor effect on L10 hepatocarcinoma cells of a potent immunoconjugate composed of the A chain of abrin and a monoclonal antibody to a hepatoma-associated antigen. , 1984, Cancer research.
[19] P. Casellas,et al. Significance of the Kinetics of Immunotoxin Cytotoxicity , 1984 .
[20] V. Raso,et al. Monoclonal Antibodies as Cell Targeted Carriers of Covalently and Non-Covalently Attached Toxins , 1984 .
[21] R. F. Beers,et al. Cell fusion : gene transfer and transformation , 1984 .
[22] S. Ramakrishnan,et al. Comparison of the selective cytotoxic effects of immunotoxins containing ricin A chain or pokeweed antiviral protein and anti-Thy 1.1 monoclonal antibodies. , 1984, Cancer research.
[23] G. Poste,et al. Receptor-Mediated Targeting of Drugs , 1984, Springer US.
[24] Jagannathan. Modern Trends in Human Leukemia , 1983 .
[25] Y. Masuho,et al. Importance of the antigen-binding valency and the nature of the cross-linking bond in ricin A-chain conjugates with antibody. , 1982, Journal of biochemistry.
[26] Y. Masuho,et al. Targeting of the antiviral protein from Phytolacca americana with an antibody. , 1982, Biochemical and biophysical research communications.
[27] Dominique,et al. Immunotoxins: Hybrid Molecules Combining High Specificity and Potent Cytotoxicity , 1982, Immunological reviews.
[28] P. Thorpe,et al. The Preparation and Cytotoxic Properties of Antibody‐Toxin Conjugates , 1982, Immunological reviews.
[29] J. Ritz,et al. Monoclonal antibody-ricin A chain conjugate selectively cytotoxic for cells bearing the common acute lymphoblastic leukemia antigen. , 1982, Cancer research.
[30] A. McMichael,et al. Monoclonal antibodies in clinical medicine , 1982 .
[31] Y. Masuho,et al. Cytotoxicity of a hybrid prepared by coupling diphtheria toxin A-chain with immunoglobulin Fab' with N,N'-o-phenylenedimaleimide. , 1981, Biochemical and biophysical research communications.
[32] D. C. Edwards,et al. Cytotoxicity acquired by conjugation of an anti-Thy1.1 monoclonal antibody and the ribosome-inactivating protein, gelonin. , 1981, European journal of biochemistry.
[33] M. Anderson,et al. Direct evidence for inter-organ transport of glutathione and that the non-filtration renal mechanism for glutathione utilization involves gamma-glutamyl transpeptidase. , 1980, Biochemical and biophysical research communications.
[34] R. Traut,et al. Addition of sulfhydryl groups to Escherichia coli ribosomes by protein modification with 2-iminothiolane (methyl 4-mercaptobutyrimidate). , 1978, Biochemistry.
[35] J Carlsson,et al. Protein thiolation and reversible protein-protein conjugation. N-Succinimidyl 3-(2-pyridyldithio)propionate, a new heterobifunctional reagent. , 1978, The Biochemical journal.
[36] G. Ellman,et al. Tissue sulfhydryl groups. , 1959, Archives of biochemistry and biophysics.