Antigen–specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs
暂无分享,去创建一个
H. Abderrahim | D. Capon | R. McGuinness | L. Green | C. E. Maynard-Currie | D. M. Louie | M. Noguchi | J. F. Hales | A. Jakobovits | M. Hardy | D. Garza | L. L. Green | M. C. Hardy | H. Tsuda | M. J. Mendez | H. Abderrahim | M. Noguchi | D. H. Smith | Y. Zeng | N. E. David | H. Sasai | D. G. Brenner | R. P. McGuinness | D. J. Capon | S. Klapholz | A. Jakobovits | Donna M. Louie | Joanna F. Hales | D. Brenner | S. Klapholz | H. Sasai | M. Mendez | D. Garza | H. Tsuda | Y. Zeng | N. David | Michael Mendez | Larry Green | Hadi Abderrahim | Masato Noguchi | Douglas H. Smith | Margaret C. Hardy | Hirohisa Tsuda | Nathaniel E. David | Dan Garza | Daniel G. Brenner | Ryan McGuinness
[1] J. Maizel,et al. Evolution of human immunoglobulin kappa J region genes. , 1982, The Journal of biological chemistry.
[2] J. Stavnezer,et al. The J kappa proximal region of the human K locus contains three uncommon V kappa genes which are arranged in opposite transcriptional polarities. , 1988, Molecular immunology.
[3] M. Tristem,et al. Oligonucleotide primers for polymerase chain reaction amplification of human immunoglobulin variable genes and design of family‐specific oligonucleotide probes , 1991, European journal of immunology.
[4] J. Y. Wang,et al. Preferential utilization of conserved immunoglobulin heavy chain variable gene segments during human fetal life. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[5] M. Yamada,et al. Preferential utilization of specific immunoglobulin heavy chain diversity and joining segments in adult human peripheral blood B lymphocytes , 1991, The Journal of experimental medicine.
[6] T. Honjo,et al. Physical map of the 3′ region of the human immunoglobulin heavy chain locus: clustering of autoantibody‐related variable segments in one haplotype. , 1991, The EMBO journal.
[7] T. Honjo,et al. Rearranged immunoglobulin heavy chain variable region (VH) pseudogene that deletes the second complementarity-determining region. , 1984, Proceedings of the National Academy of Sciences of the United States of America.
[8] Ulrich Siebenlist,et al. Structure of the human immunoglobulin μ locus: Characterization of embryonic and rearranged J and D genes , 1981, Cell.
[9] L. Reid,et al. Regulatory elements in the introns of the human HPRT gene are necessary for its expression in embryonic stem cells. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[10] N. Lonberg,et al. A transgenic mouse that expresses a diversity of human sequence heavy and light chain immunoglobulins. , 1992, Nucleic acids research.
[11] C. Tonnelle,et al. Preferential Expression of VH5 and VH6 Immunoglobulin Genes in Early Human B‐Cell Ontogeny , 1989, Scandinavian journal of immunology.
[12] A. Feeney,et al. Lack of N regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequences , 1990, The Journal of experimental medicine.
[13] G. Otten,et al. Analysis of homozygous mutant chimeric mice: deletion of the immunoglobulin heavy-chain joining region blocks B-cell development and antibody production. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[14] M. Surani,et al. Human antibody production in transgenic mice: expression from 100 kb of the human IgH locus , 1991, European journal of immunology.
[15] J D Kemp,et al. Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow , 1991, The Journal of experimental medicine.
[16] M. Neuberger,et al. Creation of Mice Expressing Human Antibody Light Chains by Introduction of a Yeast Artificial Chromosome Containing the Core Region of the Human Immunoglobulin κ Locus , 1993, Bio/Technology.
[17] J. D. Capra,et al. Human immunoglobulin heavy-chain minilocus recombination in transgenic mice: gene-segment use in mu and gamma transcripts. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[18] J. Riley,et al. Structure and physical map of 64 variable segments in the 3′ 0.8–megabase region of the human immunoglobulin heavy–chain locus , 1993, Nature Genetics.
[19] L. Green,et al. Germ-line transmission and expression of a human-derived yeast artificial chromosome , 1993, Nature.
[20] J. Flanagan,et al. The sequence of a human immunoglobulin epsilon heavy chain constant region gene, and evidence for three non‐allelic genes. , 1982, The EMBO journal.
[21] J. Loring,et al. Transgenic mice containing a human heavy chain immunoglobulin gene fragment cloned in a yeast artificial chromosome , 1993, Nature Genetics.
[22] J. Sambrook,et al. Molecular Cloning: A Laboratory Manual , 2001 .
[23] H. Zachau,et al. The Human Immunoglobulin κ Locus Consists of Two Copies That Are Organized in Opposite Polarity , 1993 .
[24] Y. Kurosawa,et al. Organization of human immunoglobulin heavy chain diversity gene loci. , 1988, The EMBO journal.
[25] M. Surani,et al. A repertoire of monoclonal antibodies with human heavy chains from transgenic mice. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[26] The V-J-intergenic region of the human kappa locus. , 1989, Biological chemistry Hoppe-Seyler.
[27] U. Surti,et al. Content and organization of the human Ig VH locus: definition of three new VH families and linkage to the Ig CH locus. , 1988, The EMBO journal.
[28] J. Kearney,et al. Sequential expression of immunoglobulin on developing mouse B lymphocytes: a systematic survey that suggests a model for the generation of immunoglobulin isotype diversity. , 1978, Journal of immunology.
[29] H. Zachau,et al. Physical map of the human immunoglobulin K locus and its implications for the mechanisms of VK-JK rearrangement. , 1987, Nucleic acids research.