Targeting the splicing of mRNA in autoimmune diseases: BAFF inhibition in Sjögren's syndrome as a proof of concept.
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P. Tak | X. Mariette | J. Chiorini | P. Tak | J. Gottenberg | J. Sibilia | S. Jacques | N. Roescher | G. Alsaleh | G. Chiocchia | P. Dreyfus | J. Sibilia | J. Vosters | J. Vosters
[1] James B. Mitchell,et al. Early responses to adenoviral-mediated transfer of the aquaporin-1 cDNA for radiation-induced salivary hypofunction , 2012, Proceedings of the National Academy of Sciences.
[2] G. Illei,et al. The expression of APRIL in Sjogren's syndrome: aberrant expression of APRIL in the salivary gland. , 2012, Rheumatology.
[3] G. Illei,et al. TACI-Fc gene therapy improves autoimmune sialadenitis but not salivary gland function in non-obese diabetic mice. , 2012, Oral diseases.
[4] G. Illei,et al. Temporal changes in salivary glands of non-obese diabetic mice as a model for Sjögren's syndrome. , 2012, Oral diseases.
[5] G. Dickson,et al. Long-term systemic administration of unconjugated morpholino oligomers for therapeutic expression of dystrophin by exon skipping in skeletal muscle: implications for cardiac muscle integrity. , 2011, Nucleic acid therapeutics.
[6] J. Bourke,et al. Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study , 2011, The Lancet.
[7] G. van Ommen,et al. Systemic administration of PRO051 in Duchenne's muscular dystrophy. , 2011, The New England journal of medicine.
[8] A. Torkamani,et al. Regulation of the B Cell Receptor Repertoire and Self-Reactivity by BAFF , 2010, The Journal of Immunology.
[9] A. Vissink,et al. Effectiveness of rituximab treatment in primary Sjögren's syndrome: a randomized, double-blind, placebo-controlled trial. , 2010, Arthritis and rheumatism.
[10] P. Tak,et al. Local expression of tumor necrosis factor-receptor 1:immunoglobulin G can induce salivary gland dysfunction in a murine model of Sjögren's syndrome , 2009, Arthritis research & therapy.
[11] S. Grey,et al. CD4+CD25+ T-Cells Control Autoimmunity in the Absence of B-Cells , 2009, Diabetes.
[12] J. She,et al. Differential gene expressions in the lacrimal gland during development and onset of keratoconjunctivitis sicca in Sjögren's syndrome (SJS)-like disease of the C57BL/6.NOD-Aec1Aec2 mouse. , 2009, Experimental eye research.
[13] X. Mariette,et al. Viruses induce high expression of BAFF by salivary gland epithelial cells through TLR‐ and type‐I IFN‐dependent and ‐independent pathways , 2008, European journal of immunology.
[14] E. Lefèvre,et al. BAFF enhances chemotaxis of primary human B cells: a particular synergy between BAFF and CXCL13 on memory B cells. , 2008, Blood.
[15] J. Pers,et al. Aberrant expression of BAFF by B lymphocytes infiltrating the salivary glands of patients with primary Sjögren's syndrome. , 2007, Arthritis and rheumatism.
[16] G. Burmester,et al. Epratuzumab (humanised anti-CD22 antibody) in primary Sjögren's syndrome: an open-label phase I/II study , 2006, Arthritis research & therapy.
[17] X. Mariette,et al. B cell-activating factor of the tumor necrosis factor family (BAFF) is expressed under stimulation by interferon in salivary gland epithelial cells in primary Sjögren's syndrome , 2006, Arthritis research & therapy.
[18] C. Lucchesi,et al. Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren's syndrome. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[19] T. Clackson,et al. Rapamycin control of transgene expression from a single AAV vector in mouse salivary glands , 2006, Gene Therapy.
[20] Marjolein Vinkenoog,et al. Reliability of computerized image analysis for the evaluation of serial synovial biopsies in randomized controlled trials in rheumatoid arthritis , 2005, Arthritis research & therapy.
[21] D. Greaves,et al. deltaBAFF, a splice isoform of BAFF, opposes full-length BAFF activity in vivo in transgenic mouse models. , 2005, Journal of immunology.
[22] X. Mariette,et al. Expression of BAFF (BLyS) in T cells infiltrating labial salivary glands from patients with Sjögren's syndrome , 2004, The Journal of pathology.
[23] C. Ware,et al. ΔBAFF, an Alternate Splice Isoform That Regulates Receptor Binding and Biopresentation of the B Cell Survival Cytokine, BAFF* , 2003, Journal of Biological Chemistry.
[24] X. Mariette,et al. The level of BLyS (BAFF) correlates with the titre of autoantibodies in human Sjögren’s syndrome , 2003, Annals of the rheumatic diseases.
[25] B. Sullenger,et al. Therapeutic potential of antisense oligonucleotides as modulators of alternative splicing , 2003 .
[26] J. Mohler,et al. Cellular Response to an Antisense-mediated Shift of Bcl-x Pre-mRNA Splicing and Antineoplastic Agents* , 2002, The Journal of Biological Chemistry.
[27] J. Tschopp,et al. Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome. , 2002, The Journal of clinical investigation.
[28] J. Tschopp,et al. Mice Transgenic for Baff Develop Lymphocytic Disorders along with Autoimmune Manifestations , 1999, The Journal of experimental medicine.
[29] R. Kole,et al. Stable alteration of pre-mRNA splicing patterns by modified U7 small nuclear RNAs. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[30] E. Cadman,et al. Sjögren's Syndrome , 1953, Medicine illustrated.