Predicting Arrhythmia‐Free Survival Using Spectral and Modified‐Moving Average Analyses of T‐Wave Alternans

Background: T‐wave alternans (TWA) is a promising electrocardiogram (ECG) predictor of sudden cardiac arrest, yet needs specialized recordings for conventional spectral analysis. Modified moving average (MMA) analysis is a new approach that can measure TWA from routine ECGs, thus widening its applicability. However, MMA‐TWA has not been calibrated against spectral TWA nor outcome in high risk patients. We hypothesized that spectral and MMA‐TWA would both predict arrhythmia‐free survival on long‐term prospective follow‐up.

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