Regional specificity of relroviral integration

[1]  D. Morris,et al.  Identification of a MMTV insertion mutation within the coding region of the Fgf-3 protooncogene. , 1997, Virology.

[2]  G. Bernardi,et al.  A compositional map of the cen-q21 region of human chromosome 21. , 1997, Gene.

[3]  F. Diella,et al.  Characterization of the INT6 mammary tumor gene product. , 1997, DNA and cell biology.

[4]  P. Hájková,et al.  The LTR, v-src, LTR provirus in H-19 hamster tumor cell line is integrated adjacent to the negative regulatory region. , 1996, Gene.

[5]  G Bernardi,et al.  The gene distribution of the human genome. , 1996, Gene.

[6]  D. Edmondson,et al.  Chromatin and transcription , 1996, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[7]  G Bernardi,et al.  Human coding and noncoding DNA: compositional correlations. , 1996, Molecular phylogenetics and evolution.

[8]  I. Su,et al.  Preferred nucleotide sequence at the integration target site of human T‐cell leukemia virus type I from patients with adult T‐cell leukemia , 1996, International journal of cancer.

[9]  L E Orgel,et al.  In vitro integration of human immunodeficiency virus type 1 cDNA into targets containing protein-induced bends. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[10]  J. Shaughnessy,et al.  Retroviral integration at the Evi-2 locus in BXH-2 myeloid leukemia cell lines disrupts Nf1 expression without changes in steady-state Ras-GTP levels , 1995, Journal of virology.

[11]  A. Marchetti,et al.  The chromosomal location of the mouse mammary tumor gene Int6 and related pseudogenes in the mouse genome. , 1995, Genomics.

[12]  C. MacArthur,et al.  Fgf-8, activated by proviral insertion, cooperates with the Wnt-1 transgene in murine mammary tumorigenesis , 1995, Journal of virology.

[13]  P. Leder,et al.  Insertional mutagenesis identifies a member of the Wnt gene family as a candidate oncogene in the mammary epithelium of int-2/Fgf-3 transgenic mice. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[14]  F. Bushman Targeting retroviral integration , 1995, Science.

[15]  A. Marchetti,et al.  Int-6, a highly conserved, widely expressed gene, is mutated by mouse mammary tumor virus in mammary preneoplasia , 1995, Journal of virology.

[16]  P. Tsichlis,et al.  Replacement of interleukin-2 (IL-2)-generated mitogenic signals by a mink cell focus-forming (MCF) or xenotropic virus-induced IL-9-dependent autocrine loop: implications for MCF virus-induced leukemogenesis , 1994, Journal of virology.

[17]  H. Varmus,et al.  DNA bending creates favored sites for retroviral integration: an explanation for preferred insertion sites in nucleosomes. , 1994, The EMBO journal.

[18]  S. Rowan,et al.  Retroviral integration within the Fli-2 locus results in inactivation of the erythroid transcription factor NF-E2 in Friend erythroleukemias: evidence that NF-E2 is essential for globin expression. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[19]  F. Bushman,et al.  Human immunodeficiency virus integrase directs integration to sites of severe DNA distortion within the nucleosome core. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[20]  J. Coffin,et al.  Distribution of targets for avian retrovirus DNA integration in vivo. , 1994, Genes & development.

[21]  G. Bernardi,et al.  Regional specificity of HTLV-I proviral integration in the human genome. , 1994, Gene.

[22]  G. Athas,et al.  Retroviral determinants of leukemogenesis. , 1994, Critical reviews in oncogenesis.

[23]  I. Casciano,et al.  Analysis of a viral integration event in a CG-rich region at the 1p36 human chromosomal site. , 1993, Gene.

[24]  P. Tsichlis,et al.  Genomic organization and expression of Tpl-2 in normal cells and Moloney murine leukemia virus-induced rat T-cell lymphomas: activation by provirus insertion , 1993, Journal of virology.

[25]  C. Gilks,et al.  Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein , 1993, Molecular and cellular biology.

[26]  H. Varmus,et al.  Simian virus 40 minichromosomes as targets for retroviral integration in vivo. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[27]  G. Bernardi,et al.  Compositional bimodality and evolution of retroviral genomes. , 1992, Gene.

[28]  A. Bernstein,et al.  Retroviral insertions downstream of the heterogeneous nuclear ribonucleoprotein A1 gene in erythroleukemia cells: evidence that A1 is not essential for cell growth , 1992, Molecular and cellular biology.

[29]  H. Kung,et al.  Transcriptional interaction between retroviral long terminal repeats (LTRs): mechanism of 5' LTR suppression and 3' LTR promoter activation of c-myc in avian B-cell lymphomas , 1992, Journal of virology.

[30]  J. Coffin,et al.  Nonrandom integration of retroviral DNA in vitro: effect of CpG methylation. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[31]  G. Bernardi,et al.  The highest gene concentrations in the human genome are in telomeric bands of metaphase chromosomes. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[32]  Harold E. Varmus,et al.  Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection , 1992, Cell.

[33]  J. Adamson,et al.  Expression of the interleukin-3 and granulocyte-macrophage colony-stimulating factor genes in Friend spleen focus-forming virus-induced erythroleukemia. , 1992, Blood.

[34]  D. Gallahan,et al.  Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells , 1992, Journal of virology.

[35]  C. Kozak,et al.  Identification of a novel gene, Vin-1, in murine leukemia virus-induced T-cell leukemias by provirus insertional mutagenesis , 1992, Journal of virology.

[36]  H. Varmus,et al.  Retroviral integration into minichromosomes in vitro. , 1992, The EMBO journal.

[37]  S. Goff,et al.  Genetics of retroviral integration. , 1992, Annual review of genetics.

[38]  D. Chalker,et al.  Ty3 integrates within the region of RNA polymerase III transcription initiation. , 1992, Genes & development.

[39]  G Bernardi,et al.  CpG islands, genes and isochores in the genomes of vertebrates. , 1991, Gene.

[40]  G. Bernardi,et al.  The isopycnic, compartmentalized integration of Rous sarcoma virus sequences. , 1991, Gene.

[41]  G Bernardi,et al.  CpG islands: features and distribution in the genomes of vertebrates. , 1991, Gene.

[42]  L. Wolff,et al.  Acute myeloid leukemia induction by amphotropic murine retrovirus (4070A): clonal integrations involve c-myb in some but not all leukemias , 1991, Journal of virology.

[43]  A. Bernstein,et al.  Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1. , 1991, Genes & development.

[44]  Anton Berns,et al.  Identification of cooperating oncogenes in Eμ-myc transgenic mice by provirus tagging , 1991, Cell.

[45]  J. Ihle,et al.  Retroviral insertions 90 kilobases proximal to the Evi-1 myeloid transforming gene activate transcription from the normal promoter , 1991, Molecular and cellular biology.

[46]  G Bernardi,et al.  The distribution of genes in the human genome. , 1991, Gene.

[47]  J. Wyke,et al.  Differences between cellular integration sites of transcribed and nontranscribed Rous sarcoma proviruses , 1991, Journal of virology.

[48]  H. Kung,et al.  Retroviral mutagenesis of cellular oncogenes: a review with insights into the mechanisms of insertional activation. , 1991, Current topics in microbiology and immunology.

[49]  P. Lazo,et al.  Virus-host interactions and the pathogenesis of murine and human oncogenic retroviruses. , 1991, Current topics in microbiology and immunology.

[50]  M. Hayman,et al.  Characterization of a novel promoter insertion in the c-rel locus , 1990, Molecular and cellular biology.

[51]  H. Robinson,et al.  Infrequent involvement of c-fos in avian leukosis virus-induced nephroblastoma , 1990, Journal of virology.

[52]  K. Harbers,et al.  Retroviral integration sites in transgenic Mov mice frequently map in the vicinity of transcribed DNA regions , 1990, Journal of virology.

[53]  R. Nusse,et al.  Wnt-3, a gene activated by proviral insertion in mouse mammary tumors, is homologous to int-1/Wnt-1 and is normally expressed in mouse embryos and adult brain. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[54]  R. Cardiff,et al.  Insertion mutation of the int-1 and int-2 loci by mouse mammary tumor virus in premalignant and malignant neoplasms from the GR mouse strain , 1990, Journal of virology.

[55]  Adrian Bird,et al.  Alternative chromatin structure at CpG islands , 1990, Cell.

[56]  G. Peters,et al.  Proviral insertions within the int-2 gene can generate multiple anomalous transcripts but leave the protein-coding domain intact , 1990, Journal of virology.

[57]  M. Breindl,et al.  Transcriptionally active genome regions are preferred targets for retrovirus integration , 1990, Journal of virology.

[58]  D. Grandgenett,et al.  Unraveling retrovirus integration , 1990, Cell.

[59]  R. Maestro,et al.  A coordinated proto-oncogene expression characterizes MCF 247 murine leukemia virus-induced T-cell lymphomas irrespectively of proviral insertion affecting myc loci. , 1990, Leukemia research.

[60]  F. Moreau-Gachelin,et al.  Spi-1 oncogene activation in Rauscher and Friend murine virus-induced acute erythroleukemias. , 1990, Leukemia.

[61]  J. S. Lee,et al.  Long-distance activation of the Myc protooncogene by provirus insertion in Mlvi-1 or Mlvi-4 in rat T-cell lymphomas. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[62]  R. Jaenisch,et al.  Retrovirus activation in embryonal carcinoma cells by cellular promoters. , 1989, Genes & development.

[63]  N. Copeland,et al.  Provirus insertion in Tpl-1, an Ets-1-related oncogene, is associated with tumor progression in Moloney murine leukemia virus-induced rat thymic lymphomas. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[64]  S. Yamamoto,et al.  Insertional activation of N-myc by endogenous Moloney-like murine retrovirus sequences in macrophage cell lines derived from myeloma cell line-macrophage hybrids , 1989, Molecular and cellular biology.

[65]  G. Peters,et al.  The mouse homolog of the hst/k-FGF gene is adjacent to int-2 and is activated by proviral insertion in some virally induced mammary tumors. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[66]  R. Lunsford,et al.  Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia , 1989, Journal of virology.

[67]  C. Melief,et al.  Retrovirally induced murine B‐cell tumors rarely show proviral integration in sites common in T‐cell tumors , 1989, International journal of cancer.

[68]  R. Jaenisch,et al.  Retrovirus-induced insertional mutation in Mov13 mice affects collagen I expression in a tissue-specific manner , 1989, Cell.

[69]  G. Peters,et al.  A putative int domain for mouse mammary tumor virus on mouse chromosome 7 is a 5' extension of int-2 , 1989, Journal of virology.

[70]  J. Bodor,et al.  The LTR, v-src, LTR provirus generated in the mammalian genome by src mRNA reverse transcription and integration , 1989, Journal of virology.

[71]  N. Copeland,et al.  Retroviral activation of a novel gene encoding a zinc finger protein in IL-3-dependent myeloid leukemia cell lines , 1988, Cell.

[72]  K. Mizuuchi,et al.  Retroviral DNA integration: Structure of an integration intermediate , 1988, Cell.

[73]  S. Ross,et al.  Endogenous mouse mammary tumor virus is expressed in several organs in addition to the lactating mammary gland , 1988, Journal of virology.

[74]  W. S. Hayward,et al.  Rapid induction of B-cell lymphomas: insertional activation of c-myb by avian leukosis virus , 1988, Journal of virology.

[75]  J. Pumphrey,et al.  Expression of the murine proto-oncogene bcl-2 is stage specific and cell-type specific. , 1988, Current topics in microbiology and immunology.

[76]  B. Sola,et al.  Frequent involvement of the fim-3 region in Friend murine leukemia virus-induced mouse myeloblastic leukemias , 1987, Journal of virology.

[77]  G. Shen-Ong,et al.  BALB/c Mice: Requirement of c-myb Activation but Lack of v-abl Involvement , 2022 .

[78]  S. Ross,et al.  The mouse mammary tumor virus long terminal repeat directs expression in epithelial and lymphoid cells of different tissues in transgenic mice , 1987, Journal of virology.

[79]  F. Galibert,et al.  Frequent c-fms activation by proviral insertion in mouse myeloblastic leukaemias , 1987, Nature.

[80]  J. Cleveland,et al.  Insertion and truncation of c-myb by murine leukemia virus in a myeloid cell line derived from cultures of normal hematopoietic cells , 1987, Journal of virology.

[81]  P. Brown,et al.  Correct integration of retroviral DNA in vitro , 1987, Cell.

[82]  G. Bernardi,et al.  Nonrandom distribution of MMTV proviral sequences in the mouse genome. , 1987, Nucleic acids research.

[83]  C. Kozak,et al.  Dsi-1, a region with frequent proviral insertions in Moloney murine leukemia virus-induced rat thymomas , 1987, Journal of virology.

[84]  R. Jaenisch,et al.  Retrovirus integration and chromatin structure: Moloney murine leukemia proviral integration sites map near DNase I-hypersensitive sites , 1987, Journal of virology.

[85]  D. Gallahan,et al.  Mammary tumorigenesis in feral mice: identification of a new int locus in mouse mammary tumor virus (Czech II)-induced mammary tumors , 1987, Journal of virology.

[86]  G. Bernardi,et al.  Genomic localization of hepatitis B virus in a human hepatoma cell line. , 1986, Nucleic acids research.

[87]  G. Bernardi,et al.  Gene distribution and nucleotide sequence organization in the mouse genome. , 1986, European journal of biochemistry.

[88]  H L Robinson,et al.  Acceptor sites for retroviral integrations map near DNase I-hypersensitive sites in chromatin , 1986, Journal of virology.

[89]  D. George,et al.  Enhanced c-Ki-ras expression associated with Friend virus integration in a bone marrow-derived mouse cell line. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[90]  B. Sefton,et al.  Expression of a new tyrosine protein kinase is stimulated by retrovirus promoter insertion , 1986, Nature.

[91]  M. Potter,et al.  Two modes of c-myb activation in virus-induced mouse myeloid tumors , 1986, Molecular and cellular biology.

[92]  H. Varmus,et al.  Identification of a provirally activated c‐Ha‐ras oncogene in an avian nephroblastoma via a novel procedure: cDNA cloning of a chimaeric viral‐host transcript. , 1986, The EMBO journal.

[93]  H. Robinson,et al.  Patterns of proviral insertion and deletion in avian leukosis virus-induced lymphomas , 1986, Journal of virology.

[94]  A. Reicin,et al.  Early clonality and high-frequency proviral integration into the c-myc locus in AKR leukemias , 1985, Journal of virology.

[95]  T. Nilsen,et al.  c-erbB activation in ALV-induced erythroblastosis: novel RNA processing and promoter insertion result in expression of an amino-truncated EGF receptor , 1985, Cell.

[96]  A. Berns,et al.  Proviral activation of the putative oncogene Pim‐1 in MuLV induced T‐cell lymphomas. , 1985, The EMBO journal.

[97]  G Bernardi,et al.  The mosaic genome of warm-blooded vertebrates. , 1985, Science.

[98]  G. Peters,et al.  Tumorigenesis by mouse mammary tumor virus: Proviral activation of a cellular gene in the common integration region int-2 , 1984, Cell.

[99]  V. Rotter,et al.  Abelson murine leukemia virus-transformed cells that lack p53 protein synthesis express aberrant p53 mRNA species , 1984, Molecular and cellular biology.

[100]  M. Groudine,et al.  Alteration of c-myc chromatin structure by avian leukosis virus integration , 1984, Nature.

[101]  H. Varmus The molecular genetics of cellular oncogenes. , 1984, Annual review of genetics.

[102]  R. Eisenman,et al.  Expression of c-myc RNA in bursal lymphoma cell lines: Identification of c-myc-encoded proteins by hybrid-selected translation , 1983, Cell.

[103]  H. Kung,et al.  Activation of the cellular oncogene c-erbB by ltr insertion: Molecular basis for induction of erythroblastosis by avian leukosis virus , 1983, Cell.

[104]  G Bernardi,et al.  The distribution of interspersed repeats is nonuniform and conserved in the mouse and human genomes. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[105]  S. Hughes Synthesis, integration, and transcription of the retroviral provirus. , 1983, Current topics in microbiology and immunology.

[106]  J. Neil Defective avian sarcoma viruses. , 1983, Current topics in microbiology and immunology.

[107]  Harold E. Varmus,et al.  Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome , 1982, Cell.

[108]  H. Varmus,et al.  Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas , 1982, Nature.

[109]  G. Bernardi,et al.  Sequence organization and genomic distribution of the major family of interspersed repeats of mouse DNA. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[110]  R. A. Swift,et al.  Specific integration of REV proviruses in avian bursal lymphomas , 1981, Nature.

[111]  S. Marcus,et al.  Quantitative of murine mammary tumor virus-related RNA in mammary tissues of low- and high-mammary-tumor-incidence mouse strains , 1981, Journal of virology.

[112]  W. S. Hayward,et al.  Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis , 1981, Nature.

[113]  J. Bishop Enemies within: the genesis of retrovirus oncogenes , 1981, Cell.

[114]  H. Temin,et al.  No apparent nucleotide sequence specificity in cellular DNA juxtaposed to retrovirus proviruses. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[115]  G Bernardi,et al.  Genomic integration of bovine leukemia provirus: comparison of persistent lymphocytosis with lymph node tumor form of enzootic. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[116]  R. Weinberg Integrated genomes of animal viruses. , 1980, Annual review of biochemistry.

[117]  G. Bernardi,et al.  Integration of bovine leukemia virus DNA in the bovine genome. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[118]  G Bernardi,et al.  An approach to the organization of eukaryotic genomes at a macromolecular level. , 1976, Journal of molecular biology.

[119]  G Bernardi,et al.  An analysis of eukaryotic genomes by density gradient centrifugation. , 1976, Journal of molecular biology.

[120]  H. Temin,et al.  The DNA provirus hypothesis. , 1976, Science.

[121]  G Bernardi,et al.  An analysis of the bovine genome by Cs2SO4-Ag density gradient centrifugation. , 1973, Journal of molecular biology.