EphB receptor activity suppresses colorectal cancer progression

[1]  Tony Pawson,et al.  Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer , 2004, Nature Genetics.

[2]  Hans Clevers,et al.  Hindgut defects and transformation of the gastro‐intestinal tract in Tcf4−/−/Tcf1−/− embryos , 2004, The EMBO journal.

[3]  Paul Polakis,et al.  EphB2 as a Therapeutic Antibody Drug Target for the Treatment of Colorectal Cancer , 2004, Cancer Research.

[4]  H. Clevers,et al.  Live and let die in the intestinal epithelium. , 2004, Current opinion in cell biology.

[5]  Pauline Chu,et al.  Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1 , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[6]  Takuji Tanaka,et al.  Microadenomatous lesions involving loss of Apc heterozygosity in the colon of adult Apc(Min/+) mice. , 2002, Cancer research.

[7]  M. Bienz Faculty Opinions recommendation of Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB. , 2002 .

[8]  Tony Pawson,et al.  β-Catenin and TCF Mediate Cell Positioning in the Intestinal Epithelium by Controlling the Expression of EphB/EphrinB , 2002, Cell.

[9]  Hans Clevers,et al.  The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells , 2002, Cell.

[10]  A. Andres,et al.  Altered mammary epithelial development, pattern formation and involution in transgenic mice expressing the EphB4 receptor tyrosine kinase. , 2002, Journal of cell science.

[11]  T. Mak,et al.  Suppression of intestinal polyps in Msh2-deficient and non-Msh2-deficient multiple intestinal neoplasia mice by a specific cyclooxygenase-2 inhibitor and by a dual cyclooxygenase-1/2 inhibitor. , 2001, Cancer research.

[12]  M. Miyaki,et al.  Frequent activation of the β‐catenin‐Tcf signaling pathway in nonfamilial colorectal carcinomas with microsatellite instability , 2001, Genes, chromosomes & cancer.

[13]  H. Clevers,et al.  Linking Colorectal Cancer to Wnt Signaling , 2000, Cell.

[14]  H. Clevers,et al.  Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1. , 1999, Science.

[15]  Bert Vogelstein,et al.  Mutational Analysis of the APC/β-Catenin/Tcf Pathway in Colorectal Cancer , 1998 .

[16]  A. Sparks,et al.  Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer. , 1998, Cancer research.

[17]  K. Kinzler,et al.  Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC−/− Colon Carcinoma , 1997, Science.

[18]  Hans Clevers,et al.  Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC , 1997, Science.

[19]  T. Pawson,et al.  Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation. , 1996, The EMBO journal.

[20]  Bert Vogelstein,et al.  APC mutations occur early during colorectal tumorigenesis , 1992, Nature.

[21]  K. Kinzler,et al.  Erratum: Multiple Intestinal Neoplasia Caused By a Mutation in the Murine Homolog of the APC Gene , 1992, Science.

[22]  H. Pitot,et al.  A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. , 1990, Science.