Rapid energy expenditure estimation for assisted and inclined loaded walking

Background Estimating energy expenditure with indirect calorimetry requires expensive equipment and provides slow and noisy measurements. Rapid estimates using wearable sensors would enable techniques like optimizing assistive devices outside a lab. Existing methods correlate data from wearable sensors to measured energy expenditure without evaluating the accuracy of the estimated energy expenditure for activity conditions or subjects not included in the correlation process. Our goal is to assess data-driven models that are capable of rapidly estimating energy expenditure for new conditions and subjects. Methods We developed models that estimated energy expenditure from two datasets during walking conditions with (1) ankle exoskeleton assistance and (2) various loads and inclines. The estimation was portable and rapid, using input features that are possible to measure with wearable sensors and restricting the input data length to a single gait cycle or four second interval. The performance of the models was evaluated for three use cases. The first case estimated energy expenditure during walking conditions for subjects with some subject specific training data available. The second case estimated all conditions in the dataset for a new subject not included in the training data. The third case estimated new conditions for a new subject. The models also ordered the magnitude of energy expenditure across all conditions for a new subject. Results The average errors in energy expenditure estimation during assisted walking conditions were 4.4%, 8.0%, and 8.1% for the three use cases, respectively. The average errors in energy expenditure estimation during inclined and loaded walking conditions were 6.1%, 9.7%, and 11.7% for the three use cases. The models ordered the magnitude of energy expenditure with a maximum and average percentage of correctly ordered conditions of 56% and 43% for assisted walking and 85% and 55% for incline and loaded walking. Conclusions Our data-driven models determined the accuracy of energy expenditure estimation for three use cases. For experiments where the accuracy of a data-driven model is sufficient, standard indirect calorimetry can be replaced. The energy expenditure ordering could aid in selecting optimal assistance conditions. The models, code, and datasets are provided for reproduction and extension of our results.

[1]  C. H. Wyndham,et al.  An equation for prediction of energy expenditure of walking and running. , 1973, Journal of applied physiology.

[2]  K B Pandolf,et al.  Metabolic energy expenditure and terrain coefficients for walking on snow. , 1976, Ergonomics.

[3]  J. Webster,et al.  Estimation of energy expenditure by a portable accelerometer. , 1983, Medicine and science in sports and exercise.

[4]  J. Brockway Derivation of formulae used to calculate energy expenditure in man. , 1987, Human nutrition. Clinical nutrition.

[5]  A. Prentice,et al.  The use of heart rate monitoring in the estimation of energy expenditure: a validation study using indirect whole-body calorimetry , 1989, British Journal of Nutrition.

[6]  A Duggan,et al.  Prediction of the metabolic cost of walking with and without loads. , 1992, Ergonomics.

[7]  J. Perry,et al.  Energy expenditure during ambulation in dysvascular and traumatic below-knee amputees: a comparison of five prosthetic feet. , 1995, Journal of rehabilitation research and development.

[8]  Jürgen Schmidhuber,et al.  Long Short-Term Memory , 1997, Neural Computation.

[9]  R. Eston,et al.  Validity of heart rate, pedometry, and accelerometry for predicting the energy cost of children's activities. , 1998, Journal of applied physiology.

[10]  B. Ainsworth,et al.  Estimation of energy expenditure using CSA accelerometers at hip and wrist sites. , 2000, Medicine and science in sports and exercise.

[11]  Arthur D Kuo,et al.  Energetics of actively powered locomotion using the simplest walking model. , 2002, Journal of biomechanical engineering.

[12]  J. Donelan,et al.  Mechanical work for step-to-step transitions is a major determinant of the metabolic cost of human walking. , 2002, The Journal of experimental biology.

[13]  Philip E. Martin,et al.  A Model of Human Muscle Energy Expenditure , 2003, Computer methods in biomechanics and biomedical engineering.

[14]  U. Ekelund,et al.  Branched equation modeling of simultaneous accelerometry and heart rate monitoring improves estimate of directly measured physical activity energy expenditure. , 2004, Journal of applied physiology.

[15]  K. Holdy Monitoring energy metabolism with indirect calorimetry: instruments, interpretation, and clinical application. , 2004, Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition.

[16]  U. Ekelund,et al.  Reliability and validity of the combined heart rate and movement sensor Actiheart , 2005, European Journal of Clinical Nutrition.

[17]  D. Bassett,et al.  Estimating energy expenditure using accelerometers , 2006, European Journal of Applied Physiology.

[18]  D. Heil Predicting Activity Energy Expenditure Using the Actical® Activity Monitor , 2006, Research quarterly for exercise and sport.

[19]  Ayman Habib,et al.  OpenSim: Open-Source Software to Create and Analyze Dynamic Simulations of Movement , 2007, IEEE Transactions on Biomedical Engineering.

[20]  S. Olney,et al.  A comparison of gait biomechanics and metabolic requirements of overground and treadmill walking in people with stroke. , 2009, Clinical biomechanics.

[21]  P. Montgomery,et al.  Validation of Heart Rate Monitor-Based Predictions of Oxygen Uptake and Energy Expenditure , 2009, Journal of strength and conditioning research.

[22]  David Andre,et al.  Machine Learning and Sensor Fusion for Estimating Continuous Energy Expenditure , 2011, AI Mag..

[23]  Sabrina S. M. Lee,et al.  Movement mechanics as a determinate of muscle structure, recruitment and coordination , 2011, Philosophical Transactions of the Royal Society B: Biological Sciences.

[24]  S. Delp,et al.  Predicting the metabolic cost of incline walking from muscle activity and walking mechanics. , 2012, Journal of biomechanics.

[25]  Tao Liu,et al.  Gait Analysis Using Wearable Sensors , 2012, Sensors.

[26]  S. Delp,et al.  Men and women adopt similar walking mechanics and muscle activation patterns during load carriage. , 2013, Journal of biomechanics.

[27]  J. Wakeling,et al.  Estimating changes in metabolic power from EMG , 2013, SpringerPlus.

[28]  Nitish Srivastava,et al.  Dropout: a simple way to prevent neural networks from overfitting , 2014, J. Mach. Learn. Res..

[29]  Rachel W Jackson,et al.  An experimental comparison of the relative benefits of work and torque assistance in ankle exoskeletons. , 2015, Journal of applied physiology.

[30]  J. Maxwell Donelan,et al.  "Body-In-The-Loop": Optimizing Device Parameters Using Measures of Instantaneous Energetic Cost , 2015, PloS one.

[31]  Seung Eel Oh,et al.  Predicting Complete Ground Reaction Forces and Moments During Gait With Insole Plantar Pressure Information Using a Wavelet Neural Network. , 2015, Journal of biomechanical engineering.

[32]  Soha Pouya,et al.  Simulating Ideal Assistive Devices to Reduce the Metabolic Cost of Running , 2016, PloS one.

[33]  Kimberly A. Ingraham,et al.  Using wearable physiological sensors to predict energy expenditure , 2017, 2017 International Conference on Rehabilitation Robotics (ICORR).

[34]  Rachel W Jackson,et al.  Human-in-the-loop optimization of exoskeleton assistance during walking , 2017, Science.

[35]  Scott Kuindersma,et al.  Human-in-the-loop Bayesian optimization of wearable device parameters , 2017, PloS one.

[36]  Scott L Delp,et al.  Simulating ideal assistive devices to reduce the metabolic cost of walking with heavy loads , 2017, PloS one.

[37]  T. Hastie,et al.  Accuracy in Wrist-Worn, Sensor-Based Measurements of Heart Rate and Energy Expenditure in a Diverse Cohort , 2016, bioRxiv.

[38]  Scott Kuindersma,et al.  Human-in-the-loop optimization of hip assistance with a soft exosuit during walking , 2018, Science Robotics.

[39]  Salman Faraji,et al.  A simple model of mechanical effects to estimate metabolic cost of human walking , 2018, Scientific Reports.