Hemostasis Management during Adult Extracorporeal Membrane Oxygenation: A Shot in the Dark?

1Department of Anesthesiology, School of Medicine, University of Maryland, 22 South Greene Street S11C00, Baltimore, MD 21201, USA 2Department of Anesthesiology, School of Medicine, University of Maryland, 22 South Greene Street S8D12, Baltimore, MD 21201, USA *Corresponding author Michael Mazzeffi, MD Assistant Professor Department of Anesthesiology School of Medicine University of Maryland 22 South Greene Street S11C00 Baltimore, MD 21201, USA Tel. 410-328-4752 Fax: 410-328-5531 E-mail: mmazzeffi@anes.umm.edu

[1]  B. Griffith,et al.  Bleeding, Transfusion, and Mortality on Extracorporeal Life Support: ECLS Working Group on Thrombosis and Hemostasis. , 2016, The Annals of thoracic surgery.

[2]  D. Jeon,et al.  Low-dose heparin during extracorporeal membrane oxygenation treatment in adults , 2015, Intensive Care Medicine.

[3]  I-Wen Wang,et al.  Extra Corporeal Membrane Oxygenation (ECMO) review of a lifesaving technology. , 2015, Journal of thoracic disease.

[4]  P. Jansz,et al.  Prospective observational study of hemostatic alterations during adult extracorporeal membrane oxygenation (ECMO) using point-of-care thromboelastometry and platelet aggregometry. , 2015, Journal of cardiothoracic and vascular anesthesia.

[5]  G. Weigel,et al.  Extracorporeal Membrane Oxygenation Induces Short-Term Loss of High-Molecular-Weight von Willebrand Factor Multimers , 2015, Anesthesia and analgesia.

[6]  P. Meybohm,et al.  Multiple Electrode Aggregometry for the Assessment of Acquired Platelet Dysfunctions during Extracorporeal Circulation , 2014, Thoracic and Cardiovascular Surgeon.

[7]  Ahmad Y. Sheikh,et al.  Resource use trends in extracorporeal membrane oxygenation in adults: an analysis of the Nationwide Inpatient Sample 1998-2009. , 2014, The Journal of thoracic and cardiovascular surgery.

[8]  R. Thiagarajan,et al.  Extracorporeal Life Support Organization Registry Report 2012 , 2013, ASAIO journal.

[9]  P. Leprince,et al.  Recombinant factor VIIa for uncontrollable bleeding in patients with extracorporeal membrane oxygenation: report on 15 cases and literature review , 2013, Critical Care.

[10]  L. Gattinoni,et al.  Monitoring anticoagulation during extracorporeal membrane oxygenation in patients with acute respiratory failure , 2013, Critical Care.

[11]  S. Stanworth,et al.  The incidence and magnitude of fibrinolytic activation in trauma patients , 2013, Journal of thrombosis and haemostasis : JTH.

[12]  G. Patterson,et al.  Fatal thrombosis after administration of activated prothrombin complex concentrates in a patient supported by extracorporeal membrane oxygenation who had received activated recombinant factor VII. , 2002, The Journal of thoracic and cardiovascular surgery.

[13]  M. Keszler,et al.  Letter to the editor: Changes in fibrinolytic factors in newborns during extracorporeal membrane oxygenation (ECMO) , 1991 .

[14]  C. Schlensak,et al.  Acquired von Willebrand syndrome in patients with extracorporeal life support (ECLS) , 2011, Intensive Care Medicine.

[15]  M. Keszler,et al.  Changes in fibrinolytic factors in newborns during extracorporeal membrane oxygenation (ECMO) , 1991, American journal of hematology.