Human pediatric B-cell acute lymphoblastic leukemias can be classified as B-1 or B-2-like based on a minimal transcriptional signature.

[1]  K. Roberts Genetics and prognosis of ALL in children vs adults. , 2018, Hematology. American Society of Hematology. Education Program.

[2]  P. Meltzer,et al.  Progenitor B-1 B-cell acute lymphoblastic leukemia is associated with collaborative mutations in 3 critical pathways. , 2017, Blood advances.

[3]  C. Mullighan,et al.  Genetic Basis of Acute Lymphoblastic Leukemia. , 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[4]  D. Casero,et al.  Distinct Genetic Networks Orchestrate the Emergence of Specific Waves of Fetal and Adult B-1 and B-2 Development. , 2016, Immunity.

[5]  Matthew E. Ritchie,et al.  limma powers differential expression analyses for RNA-sequencing and microarray studies , 2015, Nucleic acids research.

[6]  E. Montecino-Rodriguez,et al.  Murine B-1 B Cell Progenitors Initiate B-Acute Lymphoblastic Leukemia with Features of High-Risk Disease , 2014, The Journal of Immunology.

[7]  E. Montecino-Rodriguez,et al.  B-1 B cell development in the fetus and adult. , 2012, Immunity.

[8]  Christophe Benoist,et al.  Transcriptomes of the B and T Lineages Compared by Multiplatform Microarray Profiling , 2011, The Journal of Immunology.

[9]  T. Rothstein,et al.  Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+CD27+CD43+CD70− , 2011, The Journal of experimental medicine.

[10]  J. Downing,et al.  Integrated Genetic and Epigenetic Analysis of Childhood Acute Lymphoblastic Leukemia Reveals a Synergistic Role for Structural and Epigenetic Lesions In Determining Disease Phenotype , 2010 .

[11]  P. Pandolfi,et al.  Molecular Genetics of Acute Lymphoblastic Leukemia , 2009 .

[12]  W. Evans,et al.  A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study. , 2009, The Lancet. Oncology.

[13]  E. Montecino-Rodriguez,et al.  Identification of a B-1 B cell–specified progenitor , 2006, Nature Immunology.

[14]  M. Greaves,et al.  Origins of chromosome translocations in childhood leukaemia , 2003, Nature Reviews Cancer.

[15]  L. Herzenberg,et al.  Origin of murine B cell lineages. , 1993, Annual review of immunology.