The Role of NCOA4-Mediated in
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[1] Stephen A. Sastra,et al. Cysteine depletion induces pancreatic tumor ferroptosis in mice , 2020, Science.
[2] A. Chinnaiyan,et al. Radiotherapy and immunotherapy promote tumoral lipid oxidation and ferroptosis via synergistic repression of SLC7A11. , 2019, Cancer discovery.
[3] S. Dixon,et al. Prominin2 Drives Ferroptosis Resistance by Stimulating Iron Export. , 2019, Developmental cell.
[4] Qiang Liu,et al. The induction of ferroptosis by impairing STAT3/Nrf2/GPx4 signaling enhances the sensitivity of osteosarcoma cells to cisplatin , 2019, Cell biology international.
[5] Edward W. Tate,et al. FSP1 is a glutathione-independent ferroptosis suppressor , 2019, Nature.
[6] J. Olzmann,et al. The CoQ oxidoreductase FSP1 acts in parallel to GPX4 to inhibit ferroptosis , 2019, Nature.
[7] M. Ferrari,et al. Stem Cell Modeling of Neuroferritinopathy Reveals Iron as a Determinant of Senescence and Ferroptosis during Neuronal Aging , 2019, Stem cell reports.
[8] G. Latunde-Dada,et al. Programmed Cell-Death by Ferroptosis: Antioxidants as Mitigators , 2019, International journal of molecular sciences.
[9] B. Stockwell,et al. Intercellular interaction dictates cancer cell ferroptosis via NF2–YAP signalling , 2019, Nature.
[10] J. Chi,et al. Kinome screen of ferroptosis reveals a novel role of ATM in regulating iron metabolism , 2019, Cell Death & Differentiation.
[11] T. Iwamoto,et al. Involvement of cigarette smoke-induced epithelial cell ferroptosis in COPD pathogenesis , 2019, Nature Communications.
[12] T. Vanden Berghe,et al. Targeting Ferroptosis to Iron Out Cancer. , 2019, Cancer cell.
[13] J. Pouysségur,et al. Genetic ablation of the cystine transporter xCT in PDAC cells inhibits mTORC1, growth, survival and tumor formation via nutrient and oxidative stresses. , 2019, Cancer research.
[14] Xuejun Jiang,et al. Artemisinin compounds sensitize cancer cells to ferroptosis by regulating iron homeostasis , 2019, Cell Death & Differentiation.
[15] B. Stockwell,et al. Imidazole Ketone Erastin Induces Ferroptosis and Slows Tumor Growth in a Mouse Lymphoma Model. , 2019, Cell chemical biology.
[16] A. Chinnaiyan,et al. CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy , 2019, Nature.
[17] John G Doench,et al. A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis , 2019, Nature Communications.
[18] P. Wipf,et al. Ferroptosis as a Novel Therapeutic Target for Friedreich’s Ataxia , 2019, The Journal of Pharmacology and Experimental Therapeutics.
[19] B. Li,et al. Ferroptosis, a new form of cell death: opportunities and challenges in cancer , 2019, Journal of Hematology & Oncology.
[20] B. Stockwell,et al. The Hallmarks of Ferroptosis , 2019, Annual Review of Cancer Biology.
[21] Yong Hu,et al. Deferoxamine promotes recovery of traumatic spinal cord injury by inhibiting ferroptosis , 2019, Neural regeneration research.
[22] A. Atri. The Alzheimer's Disease Clinical Spectrum: Diagnosis and Management. , 2019, The Medical clinics of North America.
[23] Changlian Zhu,et al. The Potential Role of Ferroptosis in Neonatal Brain Injury , 2019, Front. Neurosci..
[24] M. Fleming,et al. NCOA4 maintains murine erythropoiesis via cell autonomous and non-autonomous mechanisms , 2019, Haematologica.
[25] Jia-Yi Li,et al. Lactoferrin ameliorates dopaminergic neurodegeneration and motor deficits in MPTP-treated mice , 2018, Redox biology.
[26] J. Mancias,et al. The Role of NCOA4-Mediated Ferritinophagy in Health and Disease , 2018, Pharmaceuticals.
[27] Feng Zhang,et al. Activation of ferritinophagy is required for the RNA-binding protein ELAVL1/HuR to regulate ferroptosis in hepatic stellate cells , 2018, Autophagy.
[28] G. Verdile,et al. Dysregulation of Neuronal Iron Homeostasis as an Alternative Unifying Effect of Mutations Causing Familial Alzheimer’s Disease , 2018, Front. Neurosci..
[29] A. Brech,et al. Starvation induces rapid degradation of selective autophagy receptors by endosomal microautophagy , 2018, The Journal of cell biology.
[30] T. Malm,et al. Targeting Nrf2 to Suppress Ferroptosis and Mitochondrial Dysfunction in Neurodegeneration , 2018, Front. Neurosci..
[31] T. Vanden Berghe,et al. Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma , 2018, The Journal of clinical investigation.
[32] Wei‐Chao Chang,et al. Heme oxygenase-1 mediates BAY 11-7085 induced ferroptosis. , 2018, Cancer letters.
[33] L. Defebvre,et al. Could Conservative Iron Chelation Lead to Neuroprotection in Amyotrophic Lateral Sclerosis? , 2017, Antioxidants & redox signaling.
[34] Idhaliz Flores,et al. Expression and function of nuclear receptor coactivator 4 isoforms in transformed endometriotic and malignant ovarian cells , 2017, Oncotarget.
[35] A. Walch,et al. Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis , 2017, Cell.
[36] Zhan-You Wang,et al. α-Lipoic acid improves abnormal behavior by mitigation of oxidative stress, inflammation, ferroptosis, and tauopathy in P301S Tau transgenic mice , 2017, Redox biology.
[37] A. Gianoncelli,et al. Expression and characterization of the ferritin binding domain of Nuclear Receptor Coactivator-4 (NCOA4). , 2017, Biochimica et biophysica acta. General subjects.
[38] D. Sabatini,et al. NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis , 2017, Nature.
[39] B. Stockwell,et al. Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease , 2017, Cell.
[40] A. Bush,et al. Tau-mediated iron export prevents ferroptotic damage after ischemic stroke , 2017, Molecular Psychiatry.
[41] R. Xavier,et al. Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9. , 2017, Cell reports.
[42] A. Bush,et al. Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis , 2017, Redox biology.
[43] M. Rauh,et al. Nrf2-Keap1 pathway promotes cell proliferation and diminishes ferroptosis , 2017, Oncogenesis.
[44] Jill P. Mesirov,et al. Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway , 2017, Nature.
[45] Stuart L. Schreiber,et al. Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition , 2017, Nature.
[46] P. Shaw,et al. The role of mitochondria in amyotrophic lateral sclerosis , 2017, Neuroscience Letters.
[47] M. Bauer,et al. Metabolic Adaptation Establishes Disease Tolerance to Sepsis , 2017, Cell.
[48] S. Hersch,et al. KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients , 2017, Proceedings of the National Academy of Sciences.
[49] Qian Wu,et al. Supporting Information Characterization of Ferroptosis in Murine Models of Hemochromatosis , 2017 .
[50] Maneesh C. Patel,et al. Brain iron chelation by deferiprone in a phase 2 randomised double-blinded placebo controlled clinical trial in Parkinson’s disease , 2017, Scientific Reports.
[51] C. Philpott,et al. PCBP1 and NCOA4 regulate erythroid iron storage and heme biosynthesis , 2017, The Journal of clinical investigation.
[52] B. Stockwell,et al. Inhibition of neuronal ferroptosis protects hemorrhagic brain. , 2017, JCI insight.
[53] G. Ning,et al. Iron addiction: A novel therapeutic target in ovarian cancer , 2017, Oncogene.
[54] J. Mancias,et al. The Role of Autophagy in Cancer. , 2017, Annual review of cancer biology.
[55] Blaine R. Roberts,et al. Glutathione peroxidase 4: a new player in neurodegeneration? , 2017, Molecular Psychiatry.
[56] Qitao Ran,et al. Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration , 2017, Redox biology.
[57] S. Rivella,et al. A Red Carpet for Iron Metabolism , 2017, Cell.
[58] Dennis W Dickson,et al. Pathology of Neurodegenerative Diseases. , 2017, Cold Spring Harbor perspectives in biology.
[59] J. Roh,et al. Nrf2 inhibition reverses the resistance of cisplatin-resistant head and neck cancer cells to artesunate-induced ferroptosis , 2016, Redox biology.
[60] A. F. Gietl,et al. Colocalization of cerebral iron with Amyloid beta in Mild Cognitive Impairment , 2016, Scientific Reports.
[61] R. Bordet,et al. Ferroptosis, a newly characterized form of cell death in Parkinson's disease that is regulated by PKC , 2016, Neurobiology of Disease.
[62] Q. Pan,et al. Ferroptosis is an autophagic cell death process , 2016, Cell Research.
[63] B. Stockwell,et al. Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis , 2016, Proceedings of the National Academy of Sciences.
[64] K. Blennow,et al. Alzheimer's disease , 2016, The Lancet.
[65] M. Lotze,et al. Autophagy promotes ferroptosis by degradation of ferritin , 2016, Autophagy.
[66] A. Newberg,et al. N-Acetyl Cysteine May Support Dopamine Neurons in Parkinson's Disease: Preliminary Clinical and Cell Line Data , 2016, PloS one.
[67] J. Mancias,et al. Mechanisms of Selective Autophagy in Normal Physiology and Cancer. , 2016, Journal of molecular biology.
[68] Makoto Yaegashi,et al. An essential role for functional lysosomes in ferroptosis of cancer cells. , 2016, The Biochemical journal.
[69] Y. Tsuji,et al. Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease. , 2016, Trends in biochemical sciences.
[70] B. Stockwell,et al. Ferroptosis: Death by Lipid Peroxidation. , 2016, Trends in cell biology.
[71] E. White,et al. Atg7 cooperates with Pten loss to drive prostate cancer tumor growth , 2016, Genes & development.
[72] M. Santoro,et al. NCOA4 Deficiency Impairs Systemic Iron Homeostasis. , 2016, Cell reports.
[73] D. Tang,et al. Ferroptosis: process and function , 2016, Cell Death and Differentiation.
[74] D. Tang,et al. Activation of the p62‐Keap1‐NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells , 2016, Hepatology.
[75] Randall J. Platt,et al. Thyroid hormone receptor beta and NCOA4 regulate terminal erythrocyte differentiation , 2017, Proceedings of the National Academy of Sciences.
[76] Qitao Ran,et al. Ablation of the Ferroptosis Inhibitor Glutathione Peroxidase 4 in Neurons Results in Rapid Motor Neuron Degeneration and Paralysis* , 2015, The Journal of Biological Chemistry.
[77] A. Lang,et al. Parkinson's disease , 2015, The Lancet.
[78] W. Goessling,et al. Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis , 2015, eLife.
[79] Alzheimer’s Disease Neuroimaging Initiative,et al. Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE , 2015 .
[80] C. Camaschella. Iron-deficiency anemia. , 2015, The New England journal of medicine.
[81] Carmela Fimognari,et al. Broad targeting of resistance to apoptosis in cancer , 2015, Seminars in cancer biology.
[82] E. White,et al. Atg7 Overcomes Senescence and Promotes Growth of BrafV600E-Driven Melanoma. , 2015, Cancer discovery.
[83] Haichao Wang,et al. HSPB1 as a Novel Regulator of Ferroptotic Cancer Cell Death , 2015, Oncogene.
[84] A. Walch,et al. Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice , 2014, Nature Cell Biology.
[85] John A. Tallarico,et al. Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo , 2014, Nature Cell Biology.
[86] B. Leavitt,et al. Iron dysregulation in Huntington's disease , 2014, Journal of neurochemistry.
[87] M. Santoro,et al. NCOA4 transcriptional coactivator inhibits activation of DNA replication origins. , 2014, Molecular cell.
[88] G. Bloom. Amyloid-β and tau: the trigger and bullet in Alzheimer disease pathogenesis. , 2014, JAMA neurology.
[89] S. Gygi,et al. Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy , 2014, Nature.
[90] B. Stockwell,et al. Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models , 2014, Journal of the American Chemical Society.
[91] Matthew E. Welsch,et al. Regulation of Ferroptotic Cancer Cell Death by GPX4 , 2014, Cell.
[92] S. Hersch,et al. Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine , 2013, PloS one.
[93] V. Karantza,et al. Autophagy opposes p53-mediated tumor barrier to facilitate tumorigenesis in a model of PALB2-associated hereditary breast cancer. , 2013, Cancer discovery.
[94] N. Matsumoto,et al. De novo mutations in the autophagy gene WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood , 2013, Nature Genetics.
[95] Pu Wang,et al. Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain , 2013, Neurochemistry International.
[96] A. Tartakoff,et al. Mechanisms of mammalian iron homeostasis. , 2012, Biochemistry.
[97] M. R. Lamprecht,et al. Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death , 2012, Cell.
[98] R. Camp,et al. Punctate LC3B Expression Is a Common Feature of Solid Tumors and Associated with Proliferation, Metastasis, and Poor Outcome , 2011, Clinical Cancer Research.
[99] Baljit Singh,et al. Distinct function of androgen receptor coactivator ARA70α and ARA70β in mammary gland development, and in breast cancer , 2011, Breast Cancer Research and Treatment.
[100] Marc Liesa,et al. Pancreatic cancers require autophagy for tumor growth. , 2011, Genes & development.
[101] A. McKee,et al. Modulation of lipid peroxidation and mitochondrial function improves neuropathology in Huntington’s disease mice , 2011, Acta Neuropathologica.
[102] F. Ishikawa,et al. Distinct Mechanisms of Ferritin Delivery to Lysosomes in Iron-Depleted and Iron-Replete Cells , 2011, Molecular and Cellular Biology.
[103] H. Coller,et al. Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. , 2011, Genes & development.
[104] A. Manning-Boğ,et al. Glutathione Peroxidase 4 is associated with Neuromelanin in Substantia Nigra and Dystrophic Axons in Putamen of Parkinson's brain , 2011, Molecular Neurodegeneration.
[105] C. Kenific,et al. Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation , 2011, Molecular biology of the cell.
[106] Wei Li,et al. Lysosomal proteolysis is the primary degradation pathway for cytosolic ferritin and cytosolic ferritin degradation is necessary for iron exit. , 2010, Antioxidants & redox signaling.
[107] M. Willingham,et al. Ferroportin and Iron Regulation in Breast Cancer Progression and Prognosis , 2010, Science Translational Medicine.
[108] Sandra Barth,et al. Autophagy: cellular and molecular mechanisms , 2010, The Journal of pathology.
[109] Mario Amendola,et al. Oxidative stress and cell death in cells expressing L-ferritin variants causing neuroferritinopathy , 2010, Neurobiology of Disease.
[110] Charles Duyckaerts,et al. Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease , 2008, Proceedings of the National Academy of Sciences.
[111] K. Blennow,et al. Safety, efficacy, and biomarker findings of PBT2 in targeting Aβ as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial , 2008, The Lancet Neurology.
[112] B. Stockwell,et al. Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells. , 2008, Chemistry & biology.
[113] T. Babić,et al. Oxidative stress parameters in plasma of Huntington's disease patients, asymptomatic Huntington’s disease gene carriers and healthy subjects , 2007, Journal of Neurology.
[114] K. Hall,et al. Selenium level and cognitive function in rural elderly Chinese. , 2007, American journal of epidemiology.
[115] G. Musci,et al. Ferroportin‐mediated mobilization of ferritin iron precedes ferritin degradation by the proteasome , 2006, The EMBO journal.
[116] R. Cousins,et al. Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cells , 2006, Proceedings of the National Academy of Sciences.
[117] M. Linder,et al. Release of iron from ferritin requires lysosomal activity. , 2006, American journal of physiology. Cell physiology.
[118] H. Howie,et al. Neisseria meningitidis accelerates ferritin degradation in host epithelial cells to yield an essential iron source , 2004, Molecular microbiology.
[119] M. Büchler,et al. Transferrin receptor is a marker of malignant phenotype in human pancreatic cancer and in neuroendocrine carcinoma of the pancreas. , 2004, European journal of cancer.
[120] T. Montine,et al. Lipid peroxidation in aging brain and Alzheimer's disease. , 2002, Free radical biology & medicine.
[121] U. Brunk,et al. -Lipoic acid and -lipoamide prevent oxidant-induced lysosomal rupture and apoptosis , 2001 .
[122] Y. Gruenbaum,et al. Repression of ferritin expression modulates cell responsiveness to H-ras-induced growth. , 2001, Biochemical Society transactions.
[123] T. Brown,et al. Activation of androgen receptor-associated protein 70 (ARA70) mRNA expression in ovarian cancer. , 2001, Gynecologic oncology.
[124] Kou-Juey Wu,et al. Coordinated regulation of iron-controlling genes, H-ferritin and IRP2, by c-MYC. , 1999, Science.
[125] M. Beal,et al. Oxidative Stress in Huntington's Disease , 1999, Brain pathology.
[126] D. Radisky,et al. Iron in cytosolic ferritin can be recycled through lysosomal degradation in human fibroblasts. , 1998, The Biochemical journal.
[127] M. Mattson,et al. Protein modification by the lipid peroxidation product 4‐hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis patients , 1998, Annals of neurology.
[128] K. Öllinger,et al. Nutrient Deprivation of Cultured Rat Hepatocytes Increases the Desferrioxamine-available Iron Pool and Augments the Sensitivity to Hydrogen Peroxide* , 1997, The Journal of Biological Chemistry.
[129] S. Daniel,et al. Glutathione‐related enzymes in brain in Parkinson's disease , 1994, Annals of neurology.
[130] C. Marsden,et al. Increased Nigral Iron Content and Alterations in Other Metal Ions Occurring in Brain in Parkinson's Disease , 1989, Journal of neurochemistry.
[131] Yuanrong Cheng,et al. Artesunate alleviates liver fibrosis by regulating ferroptosis signaling pathway. , 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[132] M. Hayden,et al. Huntington disease , 2015, Nature Reviews Disease Primers.
[133] R. Brigelius-Flohé,et al. Glutathione peroxidases. , 2013, Biochimica et biophysica acta.
[134] F. LaFerla,et al. Alzheimer's disease. , 2010, The New England journal of medicine.
[135] W. Gerald,et al. Stimulation of prostate cancer cellular proliferation and invasion by the androgen receptor co-activator ARA70. , 2008, The American journal of pathology.
[136] G. Münch,et al. α-Lipoic acid as a new treatment option for Alzheimer’s disease — a 48 months follow-up analysis , 2007 .
[137] D. Richardson,et al. Examination of the mechanism(s) involved in doxorubicin-mediated iron accumulation in ferritin: studies using metabolic inhibitors, protein synthesis inhibitors, and lysosomotropic agents. , 2004, Molecular pharmacology.
[138] C. Marsden,et al. Increased levels of lipid hydroperoxides in the parkinsonian substantia nigra: An HPLC and ESR study , 1994, Movement disorders : official journal of the Movement Disorder Society.
[139] H. Fenton,et al. LXXIII.—Oxidation of tartaric acid in presence of iron , 1894 .