Access to Cyclobutene‐Fused Azepines Through Au‐Catalyzed Cycloisomerization of Stable Alkyne Tethered Ketene N,N‐Acetals.
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The synthesis of N-protected alkyne-tethered ketene-N,N-acetals from N-protected propargylamines and 3-bromopropiolates is demonstrated for the first time.
[1] A. Sahoo,et al. Access to cyclobutene-fused azepines through Au-catalyzed cycloisomerization of stable alkyne tethered ketene N,N-acetals. , 2014, Organic letters.