A REVIEW ON DIFFERENT HPLC ANALYSIS METHOD OF VORICONAZOLE

This review article was prepared with an aim to review different methods developed for Voriconazole drug by HPLC analytical method and strategies developed and optimized for efficient method development. There is a continuous research in this field and different researchers are exploiting different mobile phase combinations for their research work. Voriconazole is generally used as an antifungal drug under the brand name Vfend. The use of the Voriconazole as a drug essential in pharmaceutical formulations highlights the requirement for its determination and quantification with appropriate analytical methods

[1]  B. Bannwarth,et al.  Direct injection HPLC micro method for the determination of voriconazole in plasma using an internal surface reversed-phase column. , 2004, Biomedical chromatography : BMC.

[2]  Takahiro Yamada,et al.  Rapid simultaneous determination of voriconazole and its N-oxide in human plasma using an isocratic high-performance liquid chromatography method and its clinical application. , 2012, Clinical biochemistry.

[3]  K. Rao,et al.  Validated RP-HPLC Method for the Estimation of Voriconazole in Bulk and Tablet Dosage Form , 2010 .

[4]  M. Rinaldi,et al.  Development and Validation of a High-Performance Liquid Chromatography Assay for Voriconazole , 2003, Antimicrobial Agents and Chemotherapy.

[5]  K. Dooley.  Tandem mass spectrometry in the clinical chemistry laboratory. , 2003, Clinical biochemistry.

[6]  M. Rinaldi,et al.  Comparison of High-Performance Liquid Chromatographic and Microbiological Methods for Determination of Voriconazole Levels in Plasma , 2000, Antimicrobial Agents and Chemotherapy.

[7]  S. Krähenbühl,et al.  Fast and reliable determination of the antifungal drug voriconazole in plasma using monolithic silica rod liquid chromatography. , 2006, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[8]  A. I. Adams,et al.  Development and Validation of a High Performance Liquid Chromatographic Method for the Determination of Voriconazole Content in Tablets , 2005 .

[9]  B. Keevil,et al.  Validation of an Assay for Voriconazole in Serum Samples Using Liquid Chromatography-Tandem Mass Spectrometry , 2004, Therapeutic drug monitoring.

[10]  Hikaru Kobayashi,et al.  Determination of the antifungal agent voriconazole in human plasma using a simple column-switching high-performance liquid chromatography and its application to a pharmacokinetic study. , 2008, Chemical & pharmaceutical bulletin.

[11]  G. Khoschsorur,et al.  Isocratic High-Performance Liquid Chromatographic Method with Ultraviolet Detection for Simultaneous Determination of Levels of Voriconazole and Itraconazole and Its Hydroxy Metabolite in Human Serum , 2005, Antimicrobial Agents and Chemotherapy.

[12]  C. Kloft,et al.  Development and validation of an efficient HPLC method for quantification of voriconazole in plasma and microdialysate reflecting an important target site , 2008, Analytical and bioanalytical chemistry.

[13]  Z. Shihabi.  Simple Assay for Voriconazole in Serum by HPLC , 2007 .

[14]  W. Sponsel,et al.  Determination of voriconazole in aqueous humor by liquid chromatography-electrospray ionization-mass spectrometry. , 2002, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[15]  D. Stopher,et al.  Determination of a new antifungal agent, voriconazole, by multidimensional high-performance liquid chromatography with direct plasma injection onto a size-exclusion column. , 1997, Journal of chromatography. B, Biomedical sciences and applications.

[16]  J. Buer,et al.  Comparison and evaluation of a novel bioassay and high‐performance liquid chromatography for the clinical measurement of serum voriconazole concentrations , 2011, Mycoses.

[17]  Junqi He,et al.  Development and validation of a simple and rapid HPLC method for the quantitative determination of voriconazole in rat and beagle dog plasma. , 2007, Journal of chromatographic science.

[18]  R. Preiss,et al.  Determination of voriconazole in human plasma and saliva using high-performance liquid chromatography with fluorescence detection. , 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[19]  D. Breilh,et al.  Simultaneous determination of five systemic azoles in plasma by high-performance liquid chromatography with ultraviolet detection. , 2009, Journal of pharmaceutical and biomedical analysis.

[20]  J. Rao,et al.  Development and validation of a HPLC method for the determination of voriconazole in pharmaceutical formulation using an experimental design. , 2007, Talanta.

[21]  H. Klinker,et al.  Simultaneous Determination of Voriconazole and Posaconazole Concentrations in Human Plasma by High-Performance Liquid Chromatography , 2009, Antimicrobial Agents and Chemotherapy.

[22]  W. Thormann,et al.  Determination of voriconazole in human serum and plasma by micellar electrokinetic chromatography. , 2010, Journal of pharmaceutical and biomedical analysis.

[23]  D. Stopher,et al.  A rapid HPLC assay for voriconazole in human plasma. , 1998, Journal of pharmaceutical and biomedical analysis.