Supratentorial Intracerebral Schwannoma : Its Fate and Proper Management

Intracerebral schwannomas are rare and there have been none reported in Korea. We present the case of a 25-year-old man with newly developed right-side weakness and recent seizure aggravation. His seizures started approximately 9 years prior to admission. At that time, a 1 cm diameter intra-axial enhancing mass at the left precentral gyrus was found on magnetic resonance image (MRI). After 9 years of observation and treatment with antiepileptic medication, an MRI taken due to symptom aggravation revealed peri-tumoral cyst formation with tumor enlargement. The tumor was surgically removed. Subsequently, right-side weakness diminished and there was good seizure control. Pathologic diagnosis was schwannoma. Schwannoma is a very rare tumor and there are no pathognomonic findings on radiologic images; thus, it is challenging to make a correct diagnosis. However, considering the natural course and excellent prognosis after surgical treatment of this kind of intra-axial mass with benign features, early surgery for diagnosis and proper treatment is highly recommended.

[1]  T. Kiehl,et al.  Intracerebral schwannoma presenting as classic temporal lobe epilepsy. , 2012, Journal of neurosurgery.

[2]  W. Curry,et al.  Sporadic primary malignant intracerebral nerve sheath tumors: case report and literature review , 2011, Journal of Neuro-Oncology.

[3]  A. Menkü,et al.  Atypical intracerebral schwannoma mimicking glial tumor: case report. , 2009, Turkish neurosurgery.

[4]  M. Baykaner,et al.  Malignant intracerebral giant nerve sheath tumor in a 14-month-old girl with neurofibromatosis type 1: a case report , 2009, Child's Nervous System.

[5]  S. Coons,et al.  Invasive intracerebral schwannoma mimicking meningioma in a child , 2006, Child's Nervous System.

[6]  S. Powell,et al.  Intracerebral schwannoma clinically and radiologically mimicking meningioma , 2005, Pathology international.

[7]  R. Castellani,et al.  Radiologic and pathologic findings of intracerebral schwannoma. , 1998, AJNR. American journal of neuroradiology.

[8]  S. Bellocchi,et al.  Intracerebral schwannoma. Case report. , 1998 .

[9]  K. Oguro,et al.  Intracerebral Schwannoma--case report. , 1997, Neurologia medico-chirurgica.

[10]  D. Zagzag,et al.  Intracranial schwannoma presenting as a subfrontal tumor: case report. , 1997, Neurosurgery.

[11]  M. Sharma,et al.  Intracranial intraparenchymal schwannomas: a series of eight cases. , 1996, Journal of neurology, neurosurgery, and psychiatry.

[12]  J. M. Jung,et al.  Malignant intraventricular schwannoma. Case report. , 1995, Journal of neurosurgery.

[13]  P. Kelly,et al.  Intracranial parenchymal schwannoma. A clinicopathological and neuroimaging study of nine cases. , 1993, Journal of neurosurgery.

[14]  P. Bruni,et al.  Solitary intracerebral schwannoma in von Recklinghausen's disease. , 1984, Surgical neurology.

[15]  N. Ghatak,et al.  Intracerebral schwannoma. , 1975, Surgical neurology.

[16]  E. Hendrick,et al.  Intracerebral Schwannoma: Report of a Case , 1966 .

[17]  E. Hendrick,et al.  Case reports. Intracerebral schwannoma. Report of a case. , 1966, Journal of neurosurgery.