The APC/β‐catenin pathway in ulcerative colitis–related colorectal carcinomas

Although the APC/β‐catenin pathway is known to play a crucial role in sporadic colorectal carcinogenesis, its influence on ulcerative colitis (UC)–related neoplastic progression is unknown. To elucidate the role of the APC‐/β‐catenin pathway in UC‐related carcinogenesis, the authors identified APC and β‐catenin mutations in a set of UC‐related and sporadic colorectal carcinomas.

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