Homing phenotypes of tumor-specific CD8 T cells are predetermined at the tumor site by crosspresenting APCs.

[1]  Simon C Watkins,et al.  Delivery of Interferon-α Transfected Dendritic Cells into Central Nervous System Tumors Enhances the Antitumor Efficacy of Peripheral Peptide-Based Vaccines , 2004, Cancer Research.

[2]  N. Brouwenstijn,et al.  Antigen Bias in T Cell Cross-Priming , 2004, Science.

[3]  Y. Shimizu,et al.  Integrins and T cell-mediated immunity. , 2004, Annual review of immunology.

[4]  J. Simon,et al.  Dendritic Cell Immunization Route Determines CD8+ T Cell Trafficking to Inflamed Skin: Role for Tissue Microenvironment and Dendritic Cells in Establishment of T Cell-Homing Subsets1 , 2004, The Journal of Immunology.

[5]  V. Engelhard,et al.  Route of Immunization with Peptide-pulsed Dendritic Cells Controls the Distribution of Memory and Effector T Cells in Lymphoid Tissues and Determines the Pattern of Regional Tumor Control , 2003, The Journal of experimental medicine.

[6]  B. Malissen,et al.  Selective Generation of Gut Tropic T Cells in Gut-associated Lymphoid Tissue (GALT) , 2003, The Journal of experimental medicine.

[7]  P. Walker,et al.  Cutting Edge: Cross-Presentation as a Mechanism for Efficient Recruitment of Tumor-Specific CTL to the Brain 1 , 2003, The Journal of Immunology.

[8]  J. Lannes-Vieira,et al.  Essential role of VLA-4/VCAM-1 pathway in the establishment of CD8+ T-cell-mediated Trypanosoma cruzi-elicited meningoencephalitis , 2003, Journal of Neuroimmunology.

[9]  Joshy Jacob,et al.  Genetic tagging shows increased frequency and longevity of antigen-presenting, skin-derived dendritic cells in vivo , 2003, Nature Immunology.

[10]  Wolfgang Weninger,et al.  Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells , 2003, Nature.

[11]  A. Rudensky,et al.  Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity. , 2003, Immunity.

[12]  C. Ardavı́n.  Origin, precursors and differentiation of mouse dendritic cells , 2003, Nature Reviews Immunology.

[13]  P. Walker,et al.  T-cell immune responses in the brain and their relevance for cerebral malignancies , 2003, Brain Research Reviews.

[14]  Youjin Lee,et al.  Complementary Role of CD4+ T Cells and Secondary Lymphoid Tissues for Cross-presentation of Tumor Antigen to CD8+ T Cells , 2003, The Journal of experimental medicine.

[15]  A. Mowat,et al.  Anatomical basis of tolerance and immunity to intestinal antigens , 2003, Nature Reviews Immunology.

[16]  B. Engelhardt,et al.  Alpha4 integrins as therapeutic targets in autoimmune disease. , 2003, The New England journal of medicine.

[17]  M. Nishimura,et al.  Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells. , 2002, Immunity.

[18]  M. Kamm,et al.  Intestinal dendritic cells increase T cell expression of α4β7 integrin , 2002 .

[19]  D. Speiser,et al.  Tumor Growth Enhances Cross-Presentation Leading to Limited T Cell Activation without Tolerance , 2002, The Journal of experimental medicine.

[20]  E. Butcher,et al.  Rapid Acquisition of Tissue-specific Homing Phenotypes by CD4+ T Cells Activated in Cutaneous or Mucosal Lymphoid Tissues , 2002, The Journal of experimental medicine.

[21]  B. Engelhardt,et al.  Alpha4-integrin-VCAM-1 binding mediates G protein-independent capture of encephalitogenic T cell blasts to CNS white matter microvessels. , 2001, The Journal of clinical investigation.

[22]  R. Alon.  Encephalitogenic lymphoblast recruitment to resting CNS microvasculature: a natural immunosurveillance mechanism? , 2001, The Journal of clinical investigation.

[23]  Rolf M. Zinkernagel,et al.  Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction , 2001, Nature.

[24]  W. Heath,et al.  Cutting Edge: Intravenous Soluble Antigen Is Presented to CD4 T Cells by CD8− Dendritic Cells, but Cross-Presented to CD8 T Cells by CD8+ Dendritic Cells1 , 2001, The Journal of Immunology.

[25]  M. Bevan,et al.  Cd8+ but Not Cd8− Dendritic Cells Cross-Prime Cytotoxic T Cells in Vivo , 2000, The Journal of experimental medicine.

[26]  C. Mackay,et al.  T-cell function and migration. Two sides of the same coin. , 2000, The New England journal of medicine.

[27]  P. Walker,et al.  The Brain Parenchyma Is Permissive for Full Antitumor CTL Effector Function, Even in the Absence of CD4 T Cells1 , 2000, The Journal of Immunology.

[28]  C. Janeway,et al.  Differential adhesion molecule requirements for immune surveillance and inflammatory recruitment. , 2000, Brain : a journal of neurology.

[29]  M. Colombo,et al.  Dendritic Cells Infiltrating Tumors Cotransduced with Granulocyte/Macrophage Colony-Stimulating Factor (Gm-Csf) and Cd40 Ligand Genes Take up and Present Endogenous Tumor-Associated Antigens, and Prime Naive Mice for a Cytotoxic T Lymphocyte Response , 1999, The Journal of experimental medicine.

[30]  F. Lemonnier,et al.  Single H2Kb, H2Db and double H2KbDb knockout mice: peripheral CD8+ T cell repertoire and antilymphocytic choriomeningitis virus cytolytic responses , 1999, European journal of immunology.

[31]  B. Engelhardt,et al.  The development of experimental autoimmune encephalomyelitis in the mouse requires alpha4-integrin but not alpha4beta7-integrin. , 1998, The Journal of clinical investigation.

[32]  H. Ploegh,et al.  Major histocompatibility complex (MHC) class I KbDb -/- deficient mice possess functional CD8+ T cells and natural killer cells. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[33]  B. Engelhardt,et al.  Adhesion molecule phenotype of T lymphocytes in inflamed CNS , 1998, Journal of Neuroimmunology.

[34]  J. Kieffer,et al.  Cutaneous lymphocyte antigen is a specialized form of PSGL-1 expressed on skin-homing T cells , 1997, Nature.

[35]  B. Engelhardt,et al.  Lymphocyte Targeting of the Central Nervous System: A Review of Afferent and Efferent CNS‐Immune Pathways , 1996, Brain pathology.

[36]  D. Griffin,et al.  Regulation of lymphocyte homing into the brain during viral encephalitis at various stages of infection. , 1996, Journal of immunology.

[37]  L. Picker,et al.  Lymphocyte Homing and Homeostasis , 1996, Science.

[38]  B. Engelhardt,et al.  Lymphocytes infiltrating the CNS during inflammation display a distinctive phenotype and bind to VCAM-1 but not to MAdCAM-1. , 1995, International immunology.

[39]  K. Horgan,et al.  Regulated expression and binding of three VLA (β1) integrin receptors on T cells , 1990, Nature.

[40]  H. Pircher,et al.  Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen , 1989, Nature.

[41]  Eric J Kunkel,et al.  Chemokines and the tissue-specific migration of lymphocytes. , 2002, Immunity.

[42]  E. Butcher,et al.  Lymphocyte trafficking and regional immunity. , 1999, Advances in immunology.

[43]  H. Ploegh,et al.  Major histocompatibility complex (MHC) class I K b D b 2y2 deficient mice possess functional CD81 T cells and natural killer cells , 1998 .

[44]  Goust Jm.  Major histocompatibility complex. , 1990, Immunology series.