Antineoplastic Mitoxantrone Monitor: A Sandwiched Mixed Matrix Membrane (MMM) Based on a Luminescent MOF-Hydrogel Hybrid.

A sandwiched mixed matrix membrane (MMM) based on a metal-organic framework-hydrogel hybrid exhibits eximious performance in the detection of mitoxantrone. Parts per billion-level sensitivity and good selectivity in serum among other analogous antineoplastics have been achieved. This flexible MMM can be used for point-of-care testing drugs in a biological medium.

[1]  Bin Zhao,et al.  Ultrastable Matryoshka [Hf13] Nanocluster as a Luminescence Sensor for Concentrated Alkali and Acid. , 2019, Angewandte Chemie.

[2]  L. Cunha-Silva,et al.  Sub-ppm Amine Detection via Absorption and Luminescence Turn-On caused by Ligand Exchange in Metal Organic Frameworks. , 2019, Analytical chemistry.

[3]  P. Marriott,et al.  Homochiral Metal-Organic Frameworks-Polymer Mixed Matrix Membranes for Efficient Separation of Chiral Molecules. , 2019, Angewandte Chemie.

[4]  Zhi‐Yuan Gu,et al.  Solid-state nanopores for ion and small molecule analysis , 2019, Chinese Chemical Letters.

[5]  J. Kong,et al.  Multifunctional PVDF/CNT/GO mixed matrix membranes for ultrafiltration and fouling detection. , 2019, Journal of hazardous materials.

[6]  Jinmin Wang,et al.  Eu3+-Functionalized Covalent Organic Framework Hybrid Material as a Sensitive Turn-On Fluorescent Switch for Levofloxacin Monitoring in Serum and Urine. , 2019, Inorganic chemistry.

[7]  Qun Guan,et al.  UiO-68-PT MOF-Based Sensor and Its Mixed Matrix Membrane for Detection of HClO in Water. , 2019, Inorganic chemistry.

[8]  Xueqin Li,et al.  Constructing Unique Cross-Sectional Structured Mixed Matrix Membranes by Incorporating Ultrathin Microporous Nanosheets for Efficient CO2 Separation. , 2019, ACS applied materials & interfaces.

[9]  Bin Zhao,et al.  Stable Lanthanide-Organic Framework as a Luminescent Probe To Detect Both Histidine and Aspartic Acid in Water. , 2019, Inorganic chemistry.

[10]  Bin Zhao,et al.  Triple-Interpenetrated Lanthanide-Organic Framework as Dual Wave Bands Self-Calibrated pH Luminescent Probe. , 2019, Analytical chemistry.

[11]  Feng Li,et al.  Nucleic Acid-Functionalized Metal-Organic Framework-Based Homogeneous Electrochemical Biosensor for Simultaneous Detection of Multiple Tumor Biomarkers. , 2019, Analytical chemistry.

[12]  Yuanjing Cui,et al.  Flexible Metal-Organic Framework-Based Mixed-Matrix Membranes: A New Platform for H2 S Sensors. , 2018, Small.

[13]  C. Serre,et al.  Metal-Organic Frameworks as Efficient Oral Detoxifying Agents. , 2018, Journal of the American Chemical Society.

[14]  B. Yan,et al.  Trace Detection of Organophosphorus Chemical Warfare Agents in Wastewater and Plants by Luminescent UIO-67(Hf) and Evaluating the Bioaccumulation of Organophosphorus Chemical Warfare Agents. , 2018, ACS applied materials & interfaces.

[15]  Gregory S. Day,et al.  Luminescent sensors based on metal-organic frameworks , 2018 .

[16]  G. Fu,et al.  Sodium Alginate/Carboxyl-Functionalized Graphene Composite Hydrogel Via Neodymium Ions Coordination , 2017 .

[17]  B. Yan Lanthanide-Functionalized Metal-Organic Framework Hybrid Systems To Create Multiple Luminescent Centers for Chemical Sensing. , 2017, Accounts of chemical research.

[18]  B. Yan,et al.  A Luminescent 3d-4f-4d MOF Nanoprobe as a Diagnosis Platform for Human Occupational Exposure to Vinyl Chloride Carcinogen. , 2017, Inorganic chemistry.

[19]  U. Maitra,et al.  Luminescence Resonance Energy Transfer in a Multiple-Component, Self-Assembled Supramolecular Hydrogel. , 2017, Angewandte Chemie.

[20]  Jinyun Wang,et al.  A Water-Stable 3D Luminescent Metal-Organic Framework Based on Heterometallic [EuIII6ZnII] Clusters Showing Highly Sensitive, Selective, and Reversible Detection of Ronidazole. , 2017, Inorganic chemistry.

[21]  Zhi-Qi Zhang,et al.  Ratiometric fluorescence for sensitive and selective detection of mitoxantrone using a MIP@rQDs@SiO2 fluorescence probe , 2017 .

[22]  B. Yan,et al.  Determination of Urinary 1‐Hydroxypyrene for Biomonitoring of Human Exposure to Polycyclic Aromatic Hydrocarbons Carcinogens by a Lanthanide‐functionalized Metal‐Organic Framework Sensor , 2017 .

[23]  M. Burghammer,et al.  Synthesis and structural characterization of metal–organic frameworks with the mellitate linker M2(OH)2[C12O12H2]·2H2O (M = Al, Ga, In) MIL-116 , 2013 .

[24]  Azra Rabbani-Chadegani,et al.  Interaction of mitoxantrone, as an anticancer drug, with chromatin proteins, core histones and H1, in solution. , 2011, International journal of biological macromolecules.

[25]  A. Voulgaropoulos,et al.  Validated Assay for the Determination of Mitoxantrone in Pharmaceuticals Using Capillary Zone Electrophoresis , 2009 .

[26]  Moungi G Bawendi,et al.  A ratiometric CdSe/ZnS nanocrystal pH sensor. , 2006, Journal of the American Chemical Society.

[27]  J. Racoosin,et al.  Mitoxantrone treatment of multiple sclerosis: Safety considerations , 2005, Neurology.

[28]  H. Hartung,et al.  Mechanisms of mitoxantrone in multiple sclerosis–what is known? , 2004, Journal of the Neurological Sciences.

[29]  W. Smith,et al.  Quantitative analysis of mitoxantrone by surface-enhanced resonance Raman scattering. , 2002, Analytical chemistry.

[30]  B. Madewell,et al.  Evaluation of single-agent mitoxantrone as chemotherapy for relapsing canine lymphoma. , 1998, Journal of veterinary internal medicine.

[31]  S. M. Golabi,et al.  Polarographic determination of mitoxantrone in pharmaceutical preparations and biological media. , 1996, Talanta.