The mechanism of combinatorial approach was reviewed first and then the passive mixers and active mixers for discovering new kinds of non-metallic materials by the use of combinatorial approach were introducted. By active or passive mixing, combinatorial approach was used to find close relatinship butween structrure and property in order to dip out and find new products or new properties of materials. Cases of combinatorial approach were reviewed. Combinatorial approach had been used in multiple ranges, such as discovering new kinds of chemical materials, researching new classes of biological-medical materials and so on. The practical corresponding conclusions were made at last. MGI, Materials Genome Initiative, which is an initiative declared by USA president Obama has aroused intensive interests of materials specialists all around the world since 2011. With the central contents of Computing tools, Experimental tools and databases, MGI is proposed to serve for national safety, human beings wellfare and so on. However, the models of materials or products could be achieved by computing tools and the most important and core contents of MGI are to find the relationships between micro- and macro- structures and properties of materials by using experimental tools. The combinatorial approach of metal or non-metal materials is the means to achieve the above goal and it was reviewed in this paper so as to provide guidance for materials' discovery. The two important foundaments of MGI including the first principle for computing and high-throughout experiment method put forward the fast development of new-materials' discovery. That means, on one hand, MGI is ready to solve numerous micro- and macro- materials problems from the view of the first principle that means solving problems begins with atom-structure point as the basis of reach into materials. On the other hand, MGI combines high-throughout experiments with first-priciple together to achieve new kinds of materials' discovery. Many means include high-throught experiment integrated materials combinal-chip approach, diffusion multiple approach and additive manufacturing (3D printing) are used to solve the problems. The high-throughout expeirmental techniques are to be interviewed in this paper so as to make a solid foundation for new non-metallic materials' discovery and provide guidance for materials researchers to develop new kinds of materials.
[1]
J F Douglas,et al.
Combinatorial study of surface pattern formation in thin block copolymer films.
,
2001,
Physical review letters.
[2]
M. Gallop,et al.
Combinatorial chemistry.
,
1998,
Current Opinion in Chemical Biology.
[3]
Jack F. Douglas,et al.
High‐throughput characterization of pattern formation in symmetric diblock copolymer films
,
2001
.
[4]
Eric J Amis,et al.
Reaching beyond discovery
,
2004,
Nature materials.
[5]
Eric J. Amis,et al.
Combinatorial Materials Science for Polymer Thin-Film Dewetting
,
2000
.
[6]
J. Kohn,et al.
Exploration of polymethacrylate structure-property correlations: Advances towards combinatorial and high-throughput methods for biomaterials discovery.
,
2008,
Progress in polymer science.