Small molecule targeting FOXM1 DNA binding domain exhibits anti-tumor activity in ovarian cancer
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Zhaojian Liu | Yan Gao | Jing Wang | Zhuorong Li | Yingwei Li | Si-tu Xue | Ziying Zhou | Zai-xing Zhang
[1] Haiyang Guo,et al. Cyclin F and KIF20A, FOXM1 target genes, increase proliferation and invasion of ovarian cancer cells. , 2020, Experimental cell research.
[2] D. Schuster,et al. Modulating FOXO3 transcriptional activity by small, DBD-binding molecules , 2019, eLife.
[3] Benjamin G. Bitler,et al. Activation of Wnt signaling promotes olaparib resistant ovarian cancer , 2019, Molecular carcinogenesis.
[4] Ahmedin Jemal,et al. Cancer treatment and survivorship statistics, 2019 , 2019, CA: a cancer journal for clinicians.
[5] Xuegong Fan,et al. FOXM1 contributes to taxane resistance by regulating UHRF1-controlled cancer cell stemness , 2018, Cell Death & Disease.
[6] Jun Liang,et al. FoxM1 promotes epithelial-mesenchymal transition of hepatocellular carcinoma by targeting Snai1 , 2017, Molecular medicine reports.
[7] A. Gartel. FOXM1 in Cancer: Interactions and Vulnerabilities. , 2017, Cancer research.
[8] Yongjun Tan,et al. Suppression of FOXM1 Transcriptional Activities via a Single-Stranded DNA Aptamer Generated by SELEX , 2017, Scientific Reports.
[9] N. Vilaboa,et al. New inhibitor targeting human transcription factor HSF1: effects on the heat shock response and tumor cell survival , 2017, Nucleic acids research.
[10] Y. Gambin,et al. Small-Molecule Inhibitors of the SOX18 Transcription Factor. , 2017, Cell chemical biology.
[11] Feimeng Zheng,et al. FOXM1 recruits nuclear Aurora kinase A to participate in a positive feedback loop essential for the self-renewal of breast cancer stem cells , 2017, Oncogene.
[12] H. Ngan,et al. DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-β/SMAD4 signaling , 2016, Oncogene.
[13] Liankun Sun,et al. Computational Study on New Natural Compound Inhibitors of Pyruvate Dehydrogenase Kinases , 2016, International journal of molecular sciences.
[14] C. J. Wang,et al. Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target gene expression in vivo , 2016, Oncogene.
[15] Ash A. Alizadeh,et al. Abstract PR09: The prognostic landscape of genes and infiltrating immune cells across human cancers , 2015 .
[16] Michael V. Gormally,et al. Suppression of the FOXM1 transcriptional program via novel small molecule inhibition , 2014, Nature Communications.
[17] N. Seki,et al. Tumour‐suppressive microRNA‐24‐1 inhibits cancer cell proliferation through targeting FOXM1 in bladder cancer , 2014, FEBS letters.
[18] Zhuo-rong Li,et al. Design, synthesis and in vitro and in vivo antitumour activity of 3-benzylideneindolin-2-one derivatives, a novel class of small-molecule inhibitors of the MDM2-p53 interaction. , 2014, European journal of medicinal chemistry.
[19] Ting Liu,et al. FOXM1 Modulates Cisplatin Sensitivity by Regulating EXO1 in Ovarian Cancer , 2014, PloS one.
[20] Yi Wang,et al. Overexpression of FOXM1 predicts poor prognosis and promotes cancer cell proliferation, migration and invasion in epithelial ovarian cancer , 2014, Journal of Translational Medicine.
[21] Yongjun Tan,et al. FOXM1 promotes the epithelial to mesenchymal transition by stimulating the transcription of Slug in human breast cancer. , 2013, Cancer letters.
[22] I. Wierstra,et al. FOXM1 (Forkhead box M1) in tumorigenesis: overexpression in human cancer, implication in tumorigenesis, oncogenic functions, tumor-suppressive properties, and target of anticancer therapy. , 2013, Advances in cancer research.
[23] A. Al-Niaimi,et al. Epithelial ovarian cancer. , 2012, Obstetrics and gynecology clinics of North America.
[24] P. Aloy,et al. Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence , 2010, Nucleic acids research.
[25] Raymond Sawaya,et al. FoxM1B transcriptionally regulates vascular endothelial growth factor expression and promotes the angiogenesis and growth of glioma cells. , 2008, Cancer research.
[26] Renxiao Wang,et al. A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells. , 2005, Proceedings of the National Academy of Sciences of the United States of America.