MRSCloud: A cloud‐based MRS tool for basis set simulation

The purpose of this study is to present a cloud‐based spectral simulation tool “MRSCloud,” which allows MRS users to simulate a vendor‐specific and sequence‐specific basis set online in a convenient and time‐efficient manner. This tool can simulate basis sets for GE, Philips, and Siemens MR scanners, including conventional acquisitions and spectral editing schemes with PRESS and semi‐LASER localization at 3 T.

[1]  M. Mullins,et al.  Clinical Applications of Magnetic Resonance Spectroscopy in Brain Tumors: From Diagnosis to Treatment. , 2021, Radiologic clinics of North America.

[2]  Simulated basis sets for semi-LASER: the impact of including shaped RF pulses and magnetic field gradients , 2020, Magnetic Resonance Materials in Physics, Biology and Medicine.

[3]  Wolfgang Bogner,et al.  Spectral editing in 1H magnetic resonance spectroscopy: Experts' consensus recommendations , 2020, NMR in biomedicine.

[4]  Martin Wilson.  Adaptive baseline fitting for 1H MR spectroscopy analysis , 2020, Magnetic resonance in medicine.

[5]  William T Clarke,et al.  FSL‐MRS: An end‐to‐end spectroscopy analysis package , 2020, bioRxiv.

[6]  Martin Wilson.  Adaptive Baseline Fitting for 1H MR Spectroscopy Analysis , 2020, bioRxiv.

[7]  Georg Oeltzschner,et al.  Osprey: Open-source processing, reconstruction & estimation of magnetic resonance spectroscopy data , 2020, Journal of Neuroscience Methods.

[8]  Jon-Fredrik Nielsen,et al.  Across‐vendor standardization of semi‐LASER for single‐voxel MRS at 3T , 2019, NMR in biomedicine.

[9]  M. Terpstra,et al.  MEGA‐PRESS of GABA+: Influences of acquisition parameters , 2019, NMR in biomedicine.

[10]  Karl Landheer,et al.  Magnetic resonance Spectrum simulator (MARSS), a novel software package for fast and computationally efficient basis set simulation , 2019, NMR in biomedicine.

[11]  Li Pan,et al.  Multi-vendor standardized sequence for edited magnetic resonance spectroscopy , 2019, NeuroImage.

[12]  Stéphane Lehéricy,et al.  Cystathionine as a marker for 1p/19q codeleted gliomas by in vivo magnetic resonance spectroscopy. , 2019, Neuro-oncology.

[13]  Richard A. E. Edden,et al.  Advanced Hadamard-encoded editing of seven low-concentration brain metabolites: Principles of HERCULES , 2019, NeuroImage.

[14]  Jun Shen,et al.  Fast computation of full density matrix of multispin systems for spatially localized in vivo magnetic resonance spectroscopy , 2017, Medical physics.

[15]  Peter Jezzard,et al.  Advanced processing and simulation of MRS data using the FID appliance (FID‐A)—An open source, MATLAB‐based toolkit , 2017, Magnetic resonance in medicine.

[16]  Michael Schär,et al.  HERMES: Hadamard encoding and reconstruction of MEGA‐edited spectroscopy , 2016, Magnetic resonance in medicine.

[17]  Karl Young,et al.  Corrigendum: Proton NMR chemical shifts and coupling constants for brain metabolites. Govindaraju V, Young K, Maudsley AA, NMR Biomed. 2000; 13: 129–153 , 2015, NMR in biomedicine.

[18]  Li An,et al.  N‐acetyl‐aspartyl‐glutamate detection in the human brain at 7 Tesla by echo time optimization and improved Wiener filtering , 2014, Magnetic resonance in medicine.

[19]  Jens Frahm,et al.  Clinical proton MR spectroscopy in central nervous system disorders. , 2013, Radiology.

[20]  Peter B Barker,et al.  J‐difference editing of gamma‐aminobutyric acid (GABA): Simulated and experimental multiplet patterns , 2013, Magnetic resonance in medicine.

[21]  Dinesh Rakheja,et al.  2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated glioma patients , 2011, Nature Medicine.

[22]  M. Buonocore,et al.  MR spectroscopic studies of the brain in psychiatric disorders. , 2012, Current topics in behavioral neurosciences.

[23]  G. Bodenhausen,et al.  Selection of coherence-transfer pathways in NMR pulse experiments. 1984. , 1984, Journal of magnetic resonance.

[24]  Eva-Maria Ratai,et al.  Spectroscopic imaging with improved gradient modulated constant adiabaticity pulses on high-field clinical scanners. , 2010, Journal of magnetic resonance.

[25]  Arend Heerschap,et al.  Towards 1H-MRSI of the human brain at 7T with slice-selective adiabatic refocusing pulses , 2008, Magnetic Resonance Materials in Physics, Biology and Medicine.

[26]  Michael Schär,et al.  Optimized detection of lactate at high fields using inner volume saturation , 2006, Magnetic resonance in medicine.

[27]  Mikhail Veshtort,et al.  SPINEVOLUTION: a powerful tool for the simulation of solid and liquid state NMR experiments. , 2006, Journal of magnetic resonance.

[28]  L DelaBarre,et al.  The return of the frequency sweep: designing adiabatic pulses for contemporary NMR. , 2001, Journal of magnetic resonance.

[29]  R. de Beer,et al.  Java-based graphical user interface for MRUI, a software package for quantitation of in vivo/medical magnetic resonance spectroscopy signals , 2001, Comput. Biol. Medicine.

[30]  M Bak,et al.  SIMPSON: a general simulation program for solid-state NMR spectroscopy. , 2000, Journal of magnetic resonance.

[31]  V. Govindaraju,et al.  Proton NMR chemical shifts and coupling constants for brain metabolites , 2000, NMR in biomedicine.

[32]  G. Matson,et al.  Spectral simulations incorporating gradient coherence selection. , 1999, Journal of magnetic resonance.

[33]  M. Garwood,et al.  Simultaneous in vivo spectral editing and water suppression , 1998, NMR in biomedicine.

[34]  Hartmut Oschkinat,et al.  Geometrical representation of coherence transfer selection by pulsed field gradients in high‐resolution nuclear magnetic resonance , 1995 .

[35]  B. Meier,et al.  Computer Simulations in Magnetic Resonance. An Object-Oriented Programming Approach , 1994 .

[36]  S. Provencher.  Estimation of metabolite concentrations from localized in vivo proton NMR spectra , 1993, Magnetic resonance in medicine.

[37]  Thomas H. Mareci,et al.  Experimental study of optimal selective 180° radiofrequency pulses , 1988 .

[38]  P. Bottomley.  Spatial Localization in NMR Spectroscopy in Vivo , 1987, Annals of the New York Academy of Sciences.

[39]  A. Lent,et al.  Computer-optimized narrowband pulses for multislice imaging , 1987 .

[40]  Joseph B. Martin,et al.  Phosphoethanolamine and ethanolamine are decreased in Alzheimer's disease and Huntington's disease , 1987, Brain Research.

[41]  G. Bodenhausen,et al.  NMR spectra of some simple spin systems studied by two-dimensional fourier transformation of spin echoes , 1978 .

[42]  U. Fano.  Description of States in Quantum Mechanics by Density Matrix and Operator Techniques , 1957 .