Distribution of butanol molecules along bullfrog olfactory mucosa
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ALTHOUGH electrophysiological1 and gas chromatographic2 studies have indicated that odorant molecules drawn into the intact frog olfactory sac establish a concentration gradient along the olfactory mucosa, conclusive evidence for such gradients requires a direct determination of how the molecules are actually distributed. This requirement is met here by labelling butanol molecules with tritium and directly mapping their sorption along the mucosa.
[1] M. M. Mozell,et al. The Spatiotemporal Analysis of Odorants at the Level of the Olfactory Receptor Sheet , 1966, The Journal of general physiology.
[2] M. M. Mozell,et al. Chromatographic Separation of Odorants by the Nose: Retention Times Measured across in vivo Olfactory Mucosa , 1973, Science.