A fast and adaptive automated disease diagnosis method with an innovative neural network model

Automatic disease diagnosis systems have been used for many years. While these systems are constructed, the data used needs to be classified appropriately. For this purpose, a variety of methods have been proposed in the literature so far. As distinct from the ones in the literature, in this study, a general-purpose, fast and adaptive disease diagnosis system is developed. This newly proposed method is based on Learning Vector Quantization (LVQ) artificial neural networks which are powerful classification algorithms. In this study, the classification ability of LVQ networks is developed by embedding a reinforcement mechanism into the LVQ network in order to increase the success rate of the disease diagnosis method and reduce the decision time. The parameters of the reinforcement learning mechanism are updated in an adaptive way in the network. Thus, the loss of time due to incorrect selection of the parameters and decrement in the success rate are avoided. After the development process mentioned, the newly proposed classification technique is named "Adaptive LVQ with Reinforcement Mechanism (ALVQ-RM)". The method proposed handles data with missing values. To prove that this method did not offer a special solution for a particular disease, because of its adaptive structure, it is used both for diagnosis of breast cancer, and for diagnosis of thyroid disorders, and a correct diagnosis rate after replacing missing values using median method over 99.5% is acquired in average for both diseases. In addition, the success rate of determination of the parameters of the proposed "LVQ with Reinforcement Mechanism (LVQ-RM)" classifier, and how this determination affected the required number of iterations for acquiring that success rate are discussed with comparison to the other studies.

[1]  A. Santhakumaran,et al.  A Novel Classification Method for Diagnosis of Diabetes Mellitus Using Artificial Neural Networks , 2010, 2010 International Conference on Data Storage and Data Engineering.

[2]  D B Fogel,et al.  Evolving neural networks for detecting breast cancer. , 1995, Cancer letters.

[3]  Sheng-wei Fei,et al.  Diagnostic study on arrhythmia cordis based on particle swarm optimization-based support vector machine , 2010, Expert Syst. Appl..

[4]  Dimitrios K. Iakovidis,et al.  Fusion of fuzzy statistical distributions for classification of thyroid ultrasound patterns , 2010, Artif. Intell. Medicine.

[5]  Fevzullah Temurtas,et al.  Chest diseases diagnosis using artificial neural networks , 2010, Expert Syst. Appl..

[6]  Yuanlin Zhang,et al.  A New Approach to Automated Epileptic Diagnosis Using EEG and Probabilistic Neural Network , 2008, 2008 20th IEEE International Conference on Tools with Artificial Intelligence.

[7]  Ta-Cheng Chen,et al.  A GAs based approach for mining breast cancer pattern , 2006, Expert Syst. Appl..

[8]  Esin Dogantekin,et al.  An automatic diagnosis system based on thyroid gland: ADSTG , 2010, Expert Syst. Appl..

[9]  Fevzullah Temurtas,et al.  A comparative study on thyroid disease diagnosis using neural networks , 2009, Expert Syst. Appl..

[10]  Duane DeSieno,et al.  Adding a conscience to competitive learning , 1988, IEEE 1988 International Conference on Neural Networks.

[11]  Tomasz Hachaj Artificial Intelligence Methods for Understanding Dynamic Computer Tomography Perfusion Maps , 2010, 2010 International Conference on Complex, Intelligent and Software Intensive Systems.

[12]  Kemal Polat,et al.  A novel hybrid method based on artificial immune recognition system (AIRS) with fuzzy weighted pre-processing for thyroid disease diagnosis , 2007, Expert Syst. Appl..

[13]  S. Nedevschi,et al.  Advanced classification methods for improving the automatic diagnosis of the hepatocellular carcinoma, based on ultrasound images , 2010, 2010 IEEE International Conference on Automation, Quality and Testing, Robotics (AQTR).

[14]  M.C. Ince,et al.  An expert sytem for diagnosis breast cancer based on Principal Component Analysis method , 2008, 2008 IEEE 16th Signal Processing, Communication and Applications Conference.

[15]  Esin Dogantekin,et al.  An expert system based on Generalized Discriminant Analysis and Wavelet Support Vector Machine for diagnosis of thyroid diseases , 2011, Expert Syst. Appl..

[16]  Rafayah Mousa,et al.  Breast cancer diagnosis system based on wavelet analysis and fuzzy-neural , 2005, Expert Syst. Appl..

[17]  Anupam Shukla,et al.  Breast cancer diagnosis using Artificial Neural Network models , 2010, The 3rd International Conference on Information Sciences and Interaction Sciences.

[18]  Teuvo Kohonen,et al.  Self-Organization and Associative Memory, Third Edition , 1989, Springer Series in Information Sciences.

[19]  P. Sincak,et al.  Application of AI in Cardiology , 2010, 2010 IEEE 8th International Symposium on Applied Machine Intelligence and Informatics (SAMI).

[20]  Konstantina S. Nikita,et al.  DIAGNOSIS: A Telematics-Enabled System for Medical Image Archiving, Management, and Diagnosis Assistance , 2006, IEEE Transactions on Instrumentation and Measurement.

[21]  Moshe Sipper,et al.  A fuzzy-genetic approach to breast cancer diagnosis , 1999, Artif. Intell. Medicine.

[22]  Michael Biehl,et al.  Adaptive Relevance Matrices in Learning Vector Quantization , 2009, Neural Computation.

[23]  Mohammad Teshnehlab,et al.  Thyroid Disease Diagnosis Based on Genetic Algorithms Using PNN and SVM , 2009, 2009 3rd International Conference on Bioinformatics and Biomedical Engineering.

[24]  Kemal Polat,et al.  Breast cancer diagnosis using least square support vector machine , 2007, Digit. Signal Process..

[25]  Lijuan Liu,et al.  An Evolutionary Artificial Neural Network Approach for Breast Cancer Diagnosis , 2010, 2010 Third International Conference on Knowledge Discovery and Data Mining.

[26]  Andrei Doncescu,et al.  Feature Selection for Medical Diagnosis Using Fuzzy Artmap Classification and Intersection Conflict , 2010, 2010 IEEE 24th International Conference on Advanced Information Networking and Applications Workshops.

[27]  F. Paulin,et al.  Back Propagation Neural Network by Comparing Hidden Neurons: Case study on Breast Cancer Diagnosis , 2010 .

[28]  Alireza Osareh,et al.  Machine learning techniques to diagnose breast cancer , 2010, 2010 5th International Symposium on Health Informatics and Bioinformatics.

[29]  T. M. Nazmy,et al.  Adaptive Neuro-Fuzzy Inference System for classification of ECG signals , 2010, 2010 The 7th International Conference on Informatics and Systems (INFOS).

[30]  R.J. Almeida,et al.  Comparison of fuzzy clustering algorithms for classification , 2006, 2006 International Symposium on Evolving Fuzzy Systems.

[31]  Celso A. A. Kaestner,et al.  Automatic Detection of Arrhythmias Using Wavelets and Self-Organized Artificial Neural Networks , 2009, 2009 Ninth International Conference on Intelligent Systems Design and Applications.

[32]  Yongyi Yang,et al.  Computer-Aided Detection and Diagnosis of Breast Cancer With Mammography: Recent Advances , 2009, IEEE Transactions on Information Technology in Biomedicine.

[33]  Anupam Shukla,et al.  Diagnosis of Thyroid Disorders using Artificial Neural Networks , 2009, 2009 IEEE International Advance Computing Conference.

[34]  Feng Luan,et al.  Diagnosing Breast Cancer Based on Support Vector Machines , 2003, J. Chem. Inf. Comput. Sci..

[35]  Tulay Yildirim,et al.  Diagnosis of thyroid disease using artificial neural network methods , 2002, Proceedings of the 9th International Conference on Neural Information Processing, 2002. ICONIP '02..

[36]  K. Blekas,et al.  Continuous optimization schemes for fuzzy classification , 1997, Proceedings of 13th International Conference on Digital Signal Processing.

[37]  Lazaros S. Iliadis,et al.  Intelligent hybrid modelling towards the prognosis of abdominal pain , 2009, Int. J. Hybrid Intell. Syst..

[38]  Mehmet Korürek,et al.  ECG beat classification using particle swarm optimization and radial basis function neural network , 2010, Expert Syst. Appl..

[39]  Esin Dogantekin,et al.  An intelligent diagnosis system for diabetes on Linear Discriminant Analysis and Adaptive Network Based Fuzzy Inference System: LDA-ANFIS , 2010, Digit. Signal Process..

[40]  Kemal Polat,et al.  A new hybrid method based on fuzzy-artificial immune system and k-nn algorithm for breast cancer diagnosis , 2007, Comput. Biol. Medicine.

[41]  T. Kohonen,et al.  Statistical pattern recognition with neural networks: benchmarking studies , 1988, IEEE 1988 International Conference on Neural Networks.

[42]  Hussein A. Abbass,et al.  An evolutionary artificial neural networks approach for breast cancer diagnosis , 2002, Artif. Intell. Medicine.