The synthesizing CaZrO3 are prepared with fused zirconia powder (0.044mm), monoatomic zirconia powder (0.044mm), desilication zirconia powder (0.044mm) and calcium oxide powder (0.044mm). The effect of different moulding pressure and firing temperature on synthesizing CaZrO3 has been studied in this paper. The test results show that: The impurity composition SiO2 and Al2O3 in raw material have participated in reaction, and generated liquid, accelerated transmission quality speed of reaction. Desilication ZrO2 is the best ZrO2 raw material to synthesizing CaZrO3 in above three ZrO2 raw materials, firing temperature markedly influence the synthetic rate of CaZrO3, but moulding pressure is not this. Desilication ZrO2 and CaO as raw material, firing 1600°C for 3h, pressure at 160Mpa and one stage burning process are the best technical conditions to synthesize CaZrO3.