论文信息 - A NOTE ON THE EFFECTS OF METHOD OF ASCERTAINMENT ON SEGREGATION RATIOS

A NOTE ON THE EFFECTS OF METHOD OF ASCERTAINMENT ON SEGREGATION RATIOS

The problem of considering segregation ratios for rare conditions is considered. Methods of estimating this segregation ratio are described for the cases of complete ascertainment, and probability of ascertainment proportional to the number of affected; tests for homogeneity of the segregation ratio are also described. Some comments are made on estimation procedures described by previous workers.

C. A. Smith

[1] B. Woolf,et al. THE LOG LIKELIHOOD RATIO TEST (THE G‐TEST) , 1957, Annals of human genetics.

[2] Cedric A. B. Smith,et al. COUNTING METHODS IN GENETICAL STATISTICS , 1957 .

[3] By C. A. B. Smith,et al. A TEST FOR SEGREGATION RATIOS IN FAMILY DATA , 1956, Annals of human genetics.

[4] C. A. Smith,et al. THE ESTIMATION OF GENE FREQUENCIES IN A RANDOM‐MATING POPULATION , 1955, Annals of human genetics.

[5] N. Morton. Sequential tests for the detection of linkage. , 1955, American journal of human genetics.

[6] T. A. Bailey. LASERSON, MAX M. The American Impact on Russia 1784-1917. Pp. xii, 441. New York: The Macmillan Company, 1950. $5.00 , 1951 .

[7] J. B. S. Haldane,et al. THE ESTIMATION OF THE FREQUENCIES OF RECESSIVE CONDITIONS IN MAN , 1938 .

[8] R. Fisher. THE EFFECT OF METHODS OF ASCERTAINMENT UPON THE ESTIMATION OF FREQUENCIES , 1934 .

[9] C. A. Smith. Counting methods in genetical statistics. , 1957, Annals of human genetics.

[10] N. Bailey. The estimation of the frequencies of recessives with incomplete multiple selection. , 1951, Annals of eugenics.

[11] N. Bailey. A classification of methods of ascertainment and analysis in estimating the frequencies of recessives in man. , 1951, Annals of eugenics.

[12] T. A. Munro. Phenylketonuria; data on 47 British families. , 1947, Annals of eugenics.

[13] T. A. Munro. PHENYLKETONURIA: DATA ON FORTY-SEVEN BRITISH FAMILIES , 1947 .