Immune reconstitution inflammatory syndrome drives emergence of HIV drug resistance from multiple anatomic compartments in a person living with HIV

[1]  R. Swanstrom,et al.  HIV-1 is Transported into the Central Nervous System by Trafficking Infected Cells , 2023, Pathogens & immunity.

[2]  Krishna C. Kanchi,et al.  Characterization of Macrophage-Tropic HIV-1 Infection of Central Nervous System Cells and the Influence of Inflammation , 2022, Journal of virology.

[3]  S. Lewin,et al.  Pembrolizumab induces HIV latency reversal in people living with HIV and cancer on antiretroviral therapy , 2022, Science Translational Medicine.

[4]  J. Nabukenya,et al.  Research priorities for an HIV cure: International AIDS Society Global Scientific Strategy 2021 , 2021, Nature Medicine.

[5]  S. Lewin,et al.  Combination Immune Checkpoint Blockade Enhances IL-2 and CD107a Production from HIV-Specific T Cells Ex Vivo in People Living with HIV on Antiretroviral Therapy , 2021, The Journal of Immunology.

[6]  P. Catalán,et al.  Cerebrospinal fluid exposure to bictegravir/emtricitabine/tenofovir in HIV-1-infected patients with CNS impairment. , 2021, The Journal of antimicrobial chemotherapy.

[7]  J. Mellors,et al.  Can Broadly Neutralizing HIV-1 Antibodies Help Achieve an ART-Free Remission? , 2021, Frontiers in Immunology.

[8]  R. Siliciano,et al.  Antigen-driven clonal selection shapes the persistence of HIV-1 infected CD4+ T cells in vivo , 2020, bioRxiv.

[9]  J. Gunst,et al.  Broadly neutralizing antibodies combined with latency-reversing agents or immune modulators as strategy for HIV-1 remission. , 2020, Current opinion in HIV and AIDS.

[10]  M. Nussenzweig,et al.  Antigen-responsive CD4+ T cell clones contribute to the HIV-1 latent reservoir , 2020, bioRxiv.

[11]  S. Gianella,et al.  HIV persists throughout deep tissues with repopulation from multiple anatomical sources. , 2020, The Journal of clinical investigation.

[12]  Z. Grossman,et al.  No evidence of ongoing HIV replication or compartmentalization in tissues during combination antiretroviral therapy: Implications for HIV eradication , 2019, Science Advances.

[13]  D. Kaufmann,et al.  Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection , 2019, PLoS pathogens.

[14]  L. Ramos-Duran,et al.  The Benefit of Mirtazapine in the Treatment of Progressive Multifocal Leukoencephalopathy in a Young HIV-positive Patient: A Case Report. , 2018, Innovations in clinical neuroscience.

[15]  J. Routy,et al.  Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors , 2017, PLoS pathogens.

[16]  J. Mellors,et al.  Single-cell analysis of HIV-1 transcriptional activity reveals expression of proviruses in expanded clones during ART , 2017, Proceedings of the National Academy of Sciences.

[17]  S. Hughes,et al.  Clonally expanded CD4+ T cells can produce infectious HIV-1 in vivo , 2016, Proceedings of the National Academy of Sciences.

[18]  Jeffrey N. Martin,et al.  UC Office of the President Recent Work Title The immunologic effects of mesalamine in treated HIV-infected individuals with incomplete CD 4 + T cell recovery : a randomized crossover trial , 2014 .

[19]  A. Bar-Or,et al.  Maraviroc and JC virus-associated immune reconstitution inflammatory syndrome. , 2014, The New England journal of medicine.

[20]  Hui Li,et al.  Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection , 2008, Proceedings of the National Academy of Sciences.

[21]  John W. Mellors,et al.  Multiple, Linked Human Immunodeficiency Virus Type 1 Drug Resistance Mutations in Treatment-Experienced Patients Are Missed by Standard Genotype Analysis , 2005, Journal of Clinical Microbiology.

[22]  G Achaz,et al.  A robust measure of HIV-1 population turnover within chronically infected individuals. , 2004, Molecular biology and evolution.

[23]  J. Coffin,et al.  HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy , 1995, Science.

[24]  J. Ananworanich,et al.  Prospective International Study of Incidence and Predictors of Immune Reconstitution Inflammatory Syndrome and Death in People Living With Human Immunodeficiency Virus and Severe Lymphopenia , 2020 .

[25]  R. Swanstrom,et al.  Human Immunodeficiency Virus Type 1 RNA Detected in the Central Nervous System (CNS) After Years of Suppressive Antiretroviral Therapy Can Originate from a Replicating CNS Reservoir or Clonally Expanded Cells , 2019 .