Endocom and Cyclope - Two Smart Biomedical Sensors for Cardio-Vascular Surgery and Gastro-Enterology

In this paper we present two case studies of electronic embedded systems for biomedical applications: ENDOCOM and CYCLOPE. In the former, we designed and realized the prototype of an implantable pressure sensor for the follow-up of the abdominal aortic aneurysm treated by a stent. Numerical modeling, in vitro experiments and in vivo tests on large animal model demonstrated the successful real-time follow-up of the pressure in the aneurysm sac. In the latter, we designed an embedded active multispectral vision system for the real time detection of polyps based both on the classification of the 3D reconstruction of the polyps by SVM and the classification of the texture by boosting methods. An FPGA-based demonstrator of the system was realized. Experiments in laboratory, in vitro and in vivo on a pig were performed to obtain its performances. This system could be integrated into a wireless capsule for colorectal endoscopy.

[1]  Jack Collin,et al.  Risk of rupture in abdominal aortic aneurysm , 1994, The Lancet.

[2]  Patrick Garda,et al.  Cyclope: an integrated real-time 3D image sensor , 2004 .

[3]  P L Harris,et al.  Need for secondary interventions after endovascular repair of abdominal aortic aneurysms. Intermediate‐term follow‐up results of a European collaborative registry (EUROSTAR) , 2000, The British journal of surgery.

[4]  E. Belhaire,et al.  Smart Bi-Spectral Image Sensor for 3D Vision , 2007, 2007 IEEE Sensors.

[5]  Rodney A. White,et al.  Nature and significance of endoleaks and endotension: summary of opinions expressed at an international conference. , 2002, Journal of vascular surgery.

[6]  M. Mckusick,et al.  Computed Tomography and Ultrasound in Follow-up of Patients after Endovascular Repair of Abdominal Aortic Aneurysm , 2004, Annals of vascular surgery.

[7]  M. Allen,et al.  Micromachined endovascularly-implantable wireless aneurysm pressure sensors: from concept to clinic , 2005, The 13th International Conference on Solid-State Sensors, Actuators and Microsystems, 2005. Digest of Technical Papers. TRANSDUCERS '05..

[8]  Aquiles Tadashi Ywata de Carvalho,et al.  Fatores de morbimortalidade na cirurgia eletiva do aneurisma da aorta abdominal infra-renal: experiência de 134 casos , 2008 .

[9]  Stephane Elkouri,et al.  Most Patients with Abdominal Aortic Aneurysm Are Not Suitable for Endovascular Repair Using Currently Approved Bifurcated Stent-Grafts , 2004, Vascular and endovascular surgery.

[10]  Rainer Laur,et al.  Advanced hybrid integrated low-power telemetric pressure monitoring system for biomedical applications , 2000, Proceedings IEEE Thirteenth Annual International Conference on Micro Electro Mechanical Systems (Cat. No.00CH36308).

[11]  Ritwick Raj Bhuyan,et al.  Outcomes of surgical management of ruptured abdominal aortic aneurysm , 2006 .

[12]  Olivier Romain,et al.  A System for an Accurate 3D Reconstruction in Video Endoscopy Capsule , 2009, EURASIP J. Embed. Syst..

[13]  Samuel E. Wilson,et al.  Rupture rate of large abdominal aortic aneurysms in patients refusing or unfit for elective repair , 2002 .

[14]  D. Wenzel,et al.  Low power integrated pressure sensor system for medical applications , 1999 .

[15]  Thomas Schmitz-Rode,et al.  Intravascular pressure monitoring system , 2004 .

[16]  Til Aach,et al.  Classification of colon polyps in NBI endoscopy using vascularization features , 2009, Medical Imaging.

[17]  Qiuting Huang,et al.  A 0.5mW passive telemetry IC for biomedical applications , 1998, Proceedings of the 23rd European Solid-State Circuits Conference.

[18]  R. Bouzerar,et al.  Blood flow patterns in an anatomically realistic coronary vessel: influence of three different reconstruction methods. , 2002, Journal of biomechanics.

[19]  Ayeley P. Tchangani.  Support vector machines: a tool for pattern recognition and classification , 2005 .

[20]  P. Garda,et al.  Wireless communicative stent for follow-up of abdominal aortic aneurysm , 2006, 2006 IEEE Biomedical Circuits and Systems Conference.

[21]  Henrik Stovring,et al.  Proton Pump Inhibitor or Testing for Helicobacter pylori as the First Step for Patients Presenting with Dyspepsia? A Cluster-Randomized Trial , 2006, The American Journal of Gastroenterology.

[22]  グレゴリー ティー エー コヴァックス,et al.  Implantable biosensing transponder , 1997 .